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NCT00004568 · ClinicalTrials.gov registry record

Study of Inherited Neurological Disorders

A clinical trial of Motor Neuron Disease and Muscular Dystrophy, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Recruiting
Registry status
3,500
Enrollment target
2
Study locations

NCT00004568 is a study of Motor Neuron Disease and Muscular Dystrophy that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 3,500 participants, above the 324-participant average among 17 other Motor Neuron Disease trials with a reported enrollment target (980% higher). The trial reports 2 study locations across 2 states.

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The verdict

NCT00004568, a study of Motor Neuron Disease and Muscular Dystrophy, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

RECRUITING
Registry status
3,500 participants
Enrollment target
2
Study locations

Study Summary

This study is designed to learn more about the natural history of inherited neurological disorders and the role of heredity in their development. It will examine the genetics, symptoms, disease progression, treatment, and psychological and behavioral impact of diseases in the following categories: hereditary peripheral neuropathies; hereditary myopathies; muscular dystrophies; hereditary motor neuron disorders; mitochondrial myopathies; hereditary neurocognitive disorders; inherited neurological disorders without known diagnosis; and others. Many of these diseases, which affect the brain, spinal cord, muscles, and nerves, are rare and poorly understood. Children and adults of all ages with various inherited neurological disorders may be eligible for this study. Participants will undergo a detailed medical and family history, and a family tree will be drawn. They will also have a physical and neurological examination that may include blood test and urine tests, an EEG (brain wave recordings), psychological tests, and speech and language and rehabilitation evaluations. A blood sample or skin biopsy may be taken for genetic testing. Depending on the individual patient s symptoms, imaging tests such as X-rays, CT or MRI scans and muscle and nerve testing may also be done. Information from this study may provide a better understanding of the genetic underpinnings of these disorders, contributing to improved diagnosis, treatment, and genetic counseling, and perhaps leading to additional studies in these areas.

Study Locations (2)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Other

  • University of Mali - Bamako

Trial Details

FieldValue
Enrollment Target 3,500 participants
Start Date 2000-02-18

What the Registry Record Tells You About NCT00004568

The ClinicalTrials.gov registry entry for NCT00004568 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 3,500 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 324-participant average among 17 other Motor Neuron Disease trials with a reported enrollment target (980% higher). The listed sponsor is National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Motor Neuron Disease appearing as the primary indexed condition, and to 0 interventions.

NCT00004568 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Maryland, Other.

Frequently Asked Questions

What is clinical trial NCT00004568 about?

NCT00004568 is a clinical study titled "Study of Inherited Neurological Disorders". This study is designed to learn more about the natural history of inherited neurological disorders and the role of heredity in their development. It will examine the genetics, symptoms, disease progression, treatment, and psychological and behavioral impact of diseases in the following categories: h...

What is the current status of trial NCT00004568?

This trial is currently recruiting. The enrollment target is 3,500 participants. The study started on 2000-02-18.

What conditions does trial NCT00004568 study?

This clinical trial studies the following conditions: Motor Neuron Disease, Muscular Dystrophy, Muscular Disease, Peripheral Nervous System Disease.

Who is sponsoring clinical trial NCT00004568?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00004568 being conducted?

This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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