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NCT05413291 · ClinicalTrials.gov registry record

Natural History Protocol for Movement Disorders

A clinical trial of Parkinson's Disease and Tremor, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

Recruiting
Registry status
4,000
Enrollment target
1
Study location

NCT05413291: Recruiting study of Parkinson's Disease and Tremor, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

NCT05413291 is a study of Parkinson's Disease and Tremor that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 4,000 participants, above the 610-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (556% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05413291, a study of Parkinson's Disease and Tremor, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).

RECRUITING
Registry status
4,000 participants
Enrollment target
1
Study location

Study Summary

Background: A movement disorder is a condition that causes a person s body to move in ways that are not normal. There are different types. Some disorders cause movements people can t control, such as tics or shaking. Some cause reduced or slow movements. Movement disorders can cause disability in people. Sometimes members of the same family will have the same disorder. Researchers want to learn more about how people develop these disorders. This research could lead to better treatments. Objective: This natural history study will collect data on people with different types of movement disorders. It will also collect data on their family members. The data will support further research. Eligibility: Children and adults aged 2 years and older who have a movement disorder. Family members of people with movement disorders are also needed. Design: Participants will undergo screening. They will have a physical exam. Researchers will look at their existing medical images. Any photographs or videos of their movements will also be reviewed. Most participants will come to the NIH clinic for only 1 visit. They will answer questions about their condition. They will have normal tests used to diagnose their condition. They may have blood tests and different types of imaging scans. They may have tests to see how well their nerves function. The tests used will depend on the type of disorder they have. Family members will have some of the same tests as people with disorders. Participants will not receive any new treatments. Some participants may be asked to return for a follow-up visit. Up to 4000 people may participate.

Primary Outcome

The goal is to screen patients with movement disorders and family members of patients with movement disorders for enrollment in additional research protocols. No investigational treatments will be administered on this protocol and the NIH physicians will be playing a consultative role to the patient s primary physician.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 4,000 participants
Start Date 2022-10-17
Est. Completion 2030-12-31

What NCT05413291 shows while recruiting

NCT05413291 is an observational study that tracks outcomes without assigning an intervention. Its 4,000 participants enrollment target places it among the larger protocols in the corpus, above the 610-participant average among 158 other Parkinson's Disease trials with a reported enrollment target (556% higher).

The record links to 3 conditions, with Parkinson's Disease appearing as the primary indexed condition, and to 0 interventions.

NCT05413291 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT05413291 about?

NCT05413291 is a clinical study titled "Natural History Protocol for Movement Disorders". Background: A movement disorder is a condition that causes a person s body to move in ways that are not normal. There are different types. Some disorders cause movements people can t control, such as tics or shaking. Some cause reduced or slow movements. Movement disorders can cause disability in p...

What is the current status of trial NCT05413291?

This trial is currently recruiting. The enrollment target is 4,000 participants. The study started on 2022-10-17. Estimated completion is 2030-12-31.

What conditions does trial NCT05413291 study?

This clinical trial studies the following conditions: Parkinson's Disease, Tremor, Movement Disorder.

Who is sponsoring clinical trial NCT05413291?

This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05413291 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Parkinson's Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05413291's enrollment target sits among peer trials

4,000 6th of 158 higher than 153 of 158 other Parkinson's Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Parkinson's Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05413291, the US trial registry maintained by the National Library of Medicine. NCT05413291 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.