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NCT02435810 · ClinicalTrials.gov registry record
Inflammatory and Infectious Diseases of the Nervous System
A clinical trial of Brain Disease, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT02435810: Recruiting study of Brain Disease, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT02435810 is a study of Brain Disease that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 1,000 participants, above the 617-participant average among 8 other Brain Disease trials with a reported enrollment target (62% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02435810, a study of Brain Disease, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: \- Inflammation is how the body reacts to infection or injury. Infections or inflammation in the brain and nerves can be serious. There aren t always good tests to detect this. Researchers want to learn more about how diseases affect the brain and nerves to develop better tests and treatments. Objective: \- To learn more about how inflammation and infections hurt the brain and nervous system. Eligibility: \- People at least 2 years old with a diagnosis or suspected diagnosis of nervous system infection or inflammation. Design: * For some participants, a clinician outside of NIH will collect blood, tissue, and other samples. These will be sent to NIH and analyzed. * Other participants will have several visits to NIH. Children may not have all these tests. * Participants will have: * Medical history. * Physical and neurological exam. * Blood and urine samples collected. * Saliva collected. They will chew on a piece of sterile cotton for one minute. * Magnetic resonance imaging (MRI) scan. The scanner is a metal cylinder in a strong magnetic field. Participants will lie on a table that slides in and out of the cylinder. Participants will get a contrast agent through an intravenous (IV) catheter during the MRI. A needle will be used to guide a thin plastic tube (catheter) into an arm vein. * Lumbar puncture. Skin will be numbed and a needle will be inserted into the space between the bones in the back. Fluid will be removed. * Some participants may have optional study procedures. These may include eye tests, memory and thinking testing, tests with electrodes on the head, or skin biopsy.
Primary Outcome
To describe the natural history of inflammatory and infectious diseases of the nervous system and to investigate the relative contribution of underlying pathophysiological processes to morbidity, response to treatment and outcomes.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2015-05-06 |
| Est. Completion | 2026-11-29 |
What NCT02435810 shows while recruiting
NCT02435810 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 617-participant average among 8 other Brain Disease trials with a reported enrollment target (62% higher).
The record links to 1 condition, with Brain Disease appearing as the primary indexed condition, and to 0 interventions.
NCT02435810 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT02435810 about?
NCT02435810 is a clinical study titled "Inflammatory and Infectious Diseases of the Nervous System". Background: \- Inflammation is how the body reacts to infection or injury. Infections or inflammation in the brain and nerves can be serious. There aren t always good tests to detect this. Researchers want to learn more about how diseases affect the brain and nerves to develop better tests and trea...
What is the current status of trial NCT02435810?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2015-05-06. Estimated completion is 2026-11-29.
What conditions does trial NCT02435810 study?
This clinical trial studies the following conditions: Brain Disease.
Who is sponsoring clinical trial NCT02435810?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02435810 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02435810's enrollment target sits among peer trials
1,000 2nd of 8 the highest of 8 other Brain Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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