ACADIA Pharmaceuticals

35 total trials 3 currently recruiting 22 completed

ACADIA Pharmaceuticals sponsors 35 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 22 completed. 16 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Parkinson's Disease Psychosis, with 2 trials.

Trial Pipeline

35 total, page 1 of 1

RECRUITING Phase 2

ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

NCT07284667

RECRUITING Phase 2

Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

NCT07029581

RECRUITING Phase 2

ACP-204 in Adults With Alzheimer's Disease Psychosis

NCT06159673

ACTIVE NOT RECRUITING Phase 3

Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

NCT06173531

TERMINATED Phase 2

Extension Study of Pimavanserin in Irritability Associated With Autism Spectrum Disorder

NCT05555615

COMPLETED Phase 2

Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder

NCT05523895

TERMINATED Phase 2

An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome

NCT04988867

TERMINATED Phase 2

Evaluate the Efficacy and Safety of ACP-044 in Subjects With Pain Associated With Osteoarthritis of the Knee

NCT05008835

COMPLETED Phase 2

Evaluate the Efficacy and Safety of ACP-044 for the Treatment of Acute Postoperative Pain Following Bunionectomy

NCT04855240

TERMINATED Phase 3

Open-Label Extension Study of Trofinetide for Rett Syndrome

NCT04776746

COMPLETED Phase 4

Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

NCT04292223

COMPLETED Phase 3

Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome

NCT04279314

COMPLETED Phase 3

Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™)

NCT04181723

TERMINATED Phase 2

Study to Evaluate Safety and Daytime Sedation in Subjects With Parkinson's Disease With Neuropsychiatric Symptoms Treated With Pimavanserin or Low-Dose Quetiapine

NCT04164758

TERMINATED Phase 3

Extension Study of Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment

NCT04000009

COMPLETED Phase 3

Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment

NCT03968159

COMPLETED Phase 3

Extension Study of Pimavanserin in Adult Subjects With Neuropsychiatric Symptoms Related to Neurodegenerative Disease

NCT03623321

COMPLETED Phase 3

A Safety Study of Pimavanserin in Adult and Elderly Subjects Experiencing Neuropsychiatric Symptoms Related to Neurodegenerative Disease

NCT03575052

COMPLETED Phase 2

Safety and Efficacy of Pimavanserin in Adults With Parkinson's Disease and Depression

NCT03482882

COMPLETED Phase 3

Relapse Prevention Study of Pimavanserin in Dementia-related Psychosis

NCT03325556

TERMINATED

The INSYTE (Management of Parkinson's Disease Psychosis in Actual Practice) Study

NCT03152292

COMPLETED Phase 2

A Study of Pimavanserin for the Treatment of Agitation and Aggression in Subjects With Alzheimer's Disease

NCT03118947

TERMINATED Phase 3

Extension Study of Pimavanserin for the Adjunctive Treatment of Schizophrenia

NCT03121586

COMPLETED Phase 2

Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)

NCT03018340

COMPLETED Phase 2

Efficacy and Safety of Pimavanserin as Adjunctive Treatment for the Negative Symptoms of Schizophrenia (ADVANCE)

NCT02970305

TERMINATED Phase 2

Study to Examine the Safety and Efficacy of Pimavanserin for the Treatment of Agitation and Aggression in Alzheimer's Disease (SERENE)

NCT02992132

COMPLETED Phase 3

Efficacy and Safety of Adjunctive Pimavanserin for the Treatment of Schizophrenia (ENHANCE-1)

NCT02970292

COMPLETED Phase 3

A Study of the Safety and Efficacy of Pimavanserin in Patients With Parkinson's Disease Psychosis

NCT01174004

COMPLETED Phase 3

A Study of Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

NCT00658567

COMPLETED Phase 3

A Study of the Safety and Tolerability of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

NCT00550238

COMPLETED Phase 3

A Study of the Safety and Efficacy of Pimavanserin (ACP-103) in Patients With Parkinson's Disease Psychosis

NCT00477672

COMPLETED Phase 2

ACP-104 in Acutely Psychotic Subjects With Schizophrenia

NCT00490516

COMPLETED Phase 2

Antipsychotic and Motor Effects of ACP-103 When Administered in Combination With Haloperidol and Risperidone

NCT00361166

COMPLETED Phase 2

An Open-label Safety Study of Pimavanserin in Parkinson's Disease Patients

NCT01518309

COMPLETED Phase 2

Treatment of Hallucinosis/Psychosis in Parkinson's Disease by an Investigational Drug

NCT00087542

What the Pipeline for ACADIA Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, ACADIA Pharmaceuticals is linked to 35 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting, about 9% of the sponsor's indexed portfolio, and 22 are already marked complete, representing roughly 63% of the total.

The phase mix for ACADIA Pharmaceuticals reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for ACADIA Pharmaceuticals is Parkinson's Disease Psychosis with 2 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.