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NCT07137442 · ClinicalTrials.gov registry record
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques
A clinical trial of Tics and Functional Tics, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Recruiting
- Registry status
- 75
- Enrollment target
- 1
- Study location
NCT07137442: Recruiting study of Tics and Functional Tics, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT07137442 is a study of Tics and Functional Tics that is actively recruiting participants, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 75 participants, above the 34-participant average among 5 other Tics trials with a reported enrollment target (121% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07137442, a study of Tics and Functional Tics, is actively recruiting participants, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- RECRUITING
- Registry status
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Tics are involuntary movements and vocalizations. Some tics are organic: They are related to diagnosed disorders. Sometimes tics have other causes, such as problems with how the brain and body send and receive messages. These are called functional tics. It can be difficult to tell the difference between these 2 types of tics. Doctors need to know more so they can make more accurate diagnoses. Objective: To learn more about the difference between functional and organic tics. Eligibility: Adults aged 18 to 80 years who have a tic that causes involuntary movements. Healthy volunteers with no tics are also needed. Design: Participants will have one 4-hour clinic visit. The visit may be done in 1 or 2 days. Participants will refrain from consuming alcohol or caffeine before the visit. They may have a physical exam. Participants will wear two types of sensors: Electromyography (EMG): Adhesive disks with sensors will be attached to the skin above some muscles. These disks will record electricity in the muscles as the participant moves. Electroencephalography (EEG): Sensors will be placed on the participant s scalp. The sensors may be adhered directly, or the participant may wear an electrode cap. The sensors will detect brain waves. Participants will rest while seated in a chair. Their involuntary tics will be monitored with the EMG and EEG. Then they will be asked to make movements to mimic their tics. Healthy volunteers will also rest; then they will be asked to perform movements that mimic tics. Participants will have their blink reflex tested. EMG sensors will be placed on the muscles near the eyes. Electrical pulses will be used to stimulate blinking. Participants will answer questionnaires about their tics and their health....
Primary Outcome
To determine that the cortical excitability excitability before functional tics are different from those before other tics.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2026-03-26 |
| Est. Completion | 2034-08-01 |
What NCT07137442 shows while recruiting
NCT07137442 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 75 participants, a relatively small participant target, above the 34-participant average among 5 other Tics trials with a reported enrollment target (121% higher).
The record links to 2 conditions, with Tics appearing as the primary indexed condition, and to 0 interventions.
NCT07137442 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT07137442 about?
NCT07137442 is a clinical study titled "Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques". Background: Tics are involuntary movements and vocalizations. Some tics are organic: They are related to diagnosed disorders. Sometimes tics have other causes, such as problems with how the brain and body send and receive messages. These are called functional tics. It can be difficult to tell the d...
What is the current status of trial NCT07137442?
This trial is currently recruiting. The enrollment target is 75 participants. The study started on 2026-03-26. Estimated completion is 2034-08-01.
What conditions does trial NCT07137442 study?
This clinical trial studies the following conditions: Tics, Functional Tics.
Who is sponsoring clinical trial NCT07137442?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07137442 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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