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Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale
NCT06152549 · View on ClinicalTrials.gov ↗
Study Summary
Childhood adversity in the form of maltreatment and household dysfunction is the most important risk factor for psychopathology as well as a major risk factor for a host of medical disorders. It has been estimated that adverse childhood experiences account for 45%, 50%, 64% and 67% of the population attributable risk for childhood onset psychiatric disorders, alcoholism, depression, substance abuse and suicide attempts. There is also increasing evidence that maltreated and non-maltreated individuals with the same primary psychiatric diagnosis are clinically and neurobiologically distinct and respond differently to treatment. The investigators and others have proposed that assessment of exposure to maltreatment is imperative for prevention, targeted treatment and research. A potential barrier to the widespread collection of data regarding early life stress and childhood maltreatment is the concern that asking such probing questions, particularly on an online questionnaire, may provoke untoward reactions and create clinical problems. Therefore, the investigators have designed this observational study to test our hypothesis that answering questions about type and timing of childhood maltreatment are no more stressful than answering standardized mathematical and verbal questions, of the type asked on the Scholastic Aptitude Test (SAT). The study will include representative national samples (by age, sex, and ethnicity) from the United States (total N=500, Ages 18-65) and will be conducted online via Prolific™, which maintains a pool of research participants. Participants will be assigned randomly to one of two test sequences. * In sequence 1, the Maltreatment and Abuse Chronology of Exposure (MACE) scale will be presented toward the beginning of the session and the Math/Verbal Test toward the end. * In sequence 2, the order will be reversed. The impact of completing the MACE and standardized IQ questions will be assessed before and after each module, using the abbre
Conditions Studied
Interventions
- BEHAVIORAL Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge
- BEHAVIORAL Standardized Maths and Verbal Questions such as the ones used in SATs
- BEHAVIORAL Chronology of Perceived Discrimination Scale (CPDS)
- BEHAVIORAL International Personality Item Pool (IPIP-NEO)
Study Locations (1)
Massachusetts
- McLean Hospital through ProlificTM — Belmont
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2022-10-15 |
| Est. Completion | 2023-12-30 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06152549
The ClinicalTrials.gov registry entry for NCT06152549 describes a study currently listed as completed. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 500 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mclean Hospital, which has 160 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Stress, Psychological appearing as the primary indexed condition, and to 4 interventions — of which Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06152549 reports 1 study location spanning 1 distinct geographic area — top geographies include Massachusetts. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06152549 about?
NCT06152549 is a clinical study titled "Online Emotional Response to Completing a Childhood Maltreatment Self-report Scale". Childhood adversity in the form of maltreatment and household dysfunction is the most important risk factor for psychopathology as well as a major risk factor for a host of medical disorders. It has been estimated that adverse childhood experiences account for 45%, 50%, 64% and 67% of the population...
What is the current status of trial NCT06152549?
This trial is currently completed. The enrollment target is 500 participants. The study started on 2022-10-15. Estimated completion is 2023-12-30.
What conditions does trial NCT06152549 study?
This clinical trial studies the following conditions: Stress, Psychological, Stress, Emotional. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06152549?
The interventions under investigation include: Maltreatment and Abuse Chronology of Exposure Scale as a stress challenge (BEHAVIORAL), Standardized Maths and Verbal Questions such as the ones used in SATs (BEHAVIORAL), Chronology of Perceived Discrimination Scale (CPDS) (BEHAVIORAL), International Personality Item Pool (IPIP-NEO) (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06152549?
This trial is sponsored by Mclean Hospital, which has 160 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06152549 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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