Eastern Cooperative Oncology Group

141 total trials 4 currently recruiting 121 completed

Eastern Cooperative Oncology Group sponsors 141 registered US clinical trials on ClinicalTrials.gov, 4 of them currently recruiting, and 121 completed. 37 of these trials are in Phase 3-4 (later-stage) and 90 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Bladder Cancer, with 3 trials.

Trial Pipeline

141 total, page 1 of 3

RECRUITING NA

The ECOG-ACRIN SUPPORT Trial: Multilevel Intervention to Improve Diverse Enrollment in Cancer Clinical Trials

NCT06756607

RECRUITING Phase 3

Testing Whether High Dose Chemotherapy and Infusion of the Patients' Own Stem Cells Improves Survival in Patients With Peripheral T-cell Lymphoma Who Achieved a Complete Response at the End of the Initial Chemotherapy

NCT06724237

RECRUITING Phase 2

Daratumumab for Chemotherapy-Refractory Minimal Residual Disease in T Cell ALL

NCT05289687

RECRUITING NA

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

NCT05108298

ACTIVE NOT RECRUITING Phase 2

Testing the Investigational Agent Combination of Daratumumab, Bortezomib, and Dexamethasone Compared to the Usual Treatment of Cyclophosphamide, Bortezomib, and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients With Kidney Failure

NCT07085728

ACTIVE NOT RECRUITING Phase 2

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

NCT01415752

ACTIVE NOT RECRUITING Phase 3

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

NCT00978458

NOT YET RECRUITING Phase 3

A Randomized Phase III Study of Management of Treatment Naive Primary Melanoma in Elderly Patients

NCT07068074

NOT YET RECRUITING Phase 2

Testing the Effect of Sulforaphane, a Compound Naturally Found in Cruciferous Vegetables, on Preventing Melanoma in Patients With a Prior History of Melanoma

NCT07040280

NOT YET RECRUITING NA

A Targeted Electronic Health Approach to Reduce Fear of Recurrence in Breast Cancer Survivors (FoRtitude)

NCT07122492

TERMINATED

COVID-19 Related Financial Hardship and Distress in Women Who Decline TMIST (EA1151) Participation

NCT05076266

COMPLETED NA

Early Surgery or Standard Palliative Therapy in Treating Patients With Stage IV Breast Cancer

NCT01242800

COMPLETED Phase 2

Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy

NCT01079780

COMPLETED Phase 2

Induction Chemotherapy Followed By Cetuximab and Radiation in HPV-Associated Resectable Stage III/IV Oropharynx Cancer

NCT01084083

COMPLETED Phase 2

Dasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By Surgery

NCT00700882

COMPLETED Phase 2

AMG 706 and Octreotide in Treating Patients With Low-Grade Neuroendocrine Tumors

NCT00427349

TERMINATED Phase 2

Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer

NCT00551759

TERMINATED Phase 2

Rituximab and Combination Chemotherapy in Treating Patients With Primary Central Nervous System Lymphoma

NCT00335140

COMPLETED Phase 2

Reduced-Intensity Regimen Before Donor Bone Marrow Transplant in Treating Patients With Myelodysplastic Syndromes

NCT00045305

COMPLETED Phase 2

Rituximab and Combination Chemotherapy in Treating Patients With Stage II, Stage III, or Stage IV Diffuse Large B-Cell Non-Hodgkin's Lymphoma

NCT00274924

COMPLETED Phase 2

Bevacizumab and Combination Chemotherapy in Treating Patients With Peripheral T-Cell Lymphoma or Natural Killer Cell Neoplasms

NCT00217425

COMPLETED Phase 2

Paclitaxel and Carboplatin in Treating Patients With Locally Advanced or Metastatic Renal Cell Cancer

NCT00077129

COMPLETED Phase 2

Gemcitabine in Treating Patients With Metastatic Cancer of Unknown Primary

NCT00357630

COMPLETED

Quality of Life in Female Breast Cancer Survivors and Their Spouse, Partner, or Acquaintance

NCT00309933

COMPLETED

Study of Symptoms Caused by Cancer and Cancer Therapy in Patients With Invasive Breast, Lung, Prostate, or Colorectal Cancer

NCT00303914

COMPLETED Phase 2

Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesothelioma

NCT00101283

TERMINATED Phase 2

Cyclosporine in Treating Patients With Recurrent or Refractory Angioimmunoblastic T-Cell Lymphoma

NCT00070291

TERMINATED Phase 2

Reduced-Intensity Regimen Before Allogeneic Transplant for Patients With Relapsed Non-Hodgkin's or Hodgkin's Lymphoma

NCT00057954

COMPLETED Phase 2

Cetuximab in Treating Patients With Recurrent or Stage IIIB or Stage IV Lung Cancer

NCT00103207

COMPLETED Phase 2

Bevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal Cancer

NCT00098787

COMPLETED Phase 2

High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

NCT00082797

COMPLETED Phase 2

Vaccine Therapy Using Melanoma Peptides for Cytotoxic T Cells and Helper T Cells in Treating Patients With Metastatic Melanoma

NCT00071981

COMPLETED Phase 2

Pentostatin, Cyclophosphamide, and Rituximab Followed By Campath-1H in Patients With Relapsed or Refractory B-Cell CLL

NCT00074282

COMPLETED

Quality of Life in Postmenopausal Women Who Are Receiving Either Exemestane or Anastrozole With or Without Celecoxib for Stage I, Stage II, or Stage IIIA Primary Breast Cancer

NCT00090974

TERMINATED Phase 2

Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed Waldenstrom's Macroglobulinemia

NCT00060346

COMPLETED Phase 3

Epoetin Alfa With or Without Dexamethasone in Treating Fatigue and Anemia in Patients With Hormone-Refractory Prostate Cancer

NCT00060398

COMPLETED

Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial

NCT00897767

COMPLETED Phase 2

Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium

NCT00053209

COMPLETED Phase 2

Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Extensive-Stage Small Cell Lung Cancer

NCT00057837

COMPLETED Phase 2

Sorafenib in Treating Patients With Refractory Non-Small Cell Lung Cancer

NCT00064350

COMPLETED Phase 2

Esophagectomy in Treating Patients With High-Grade Dysplasia of the Esophagus or Stage I, Stage II, or Stage III Esophageal Cancer

NCT00063986

COMPLETED Phase 2

Interferon Alfa, Isotretinoin, and Paclitaxel in Treating Patients With Recurrent Small Cell Lung Cancer

NCT00062010

COMPLETED Phase 2

Doxorubicin and Gemcitabine in Treating Patients With Locally Recurrent or Metastatic Unresectable Renal Cell Carcinoma

NCT00068393

COMPLETED Phase 3

Rituximab in Treating Patients With Low Tumor Burden Indolent Non-Hodgkin's Lymphoma

NCT00075946

TERMINATED Phase 1

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

NCT00052884

COMPLETED Phase 2

PEG-Interferon Alfa-2b in Treating Patients With Stage IV Melanoma

NCT00049530

COMPLETED Phase 3

Isotretinoin, Interferon Alfa, and Vitamin E in Treating Patients With Stage III or Stage IV Head and Neck Cancer

NCT00054561

COMPLETED Phase 2

Chemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic Cancer

NCT00049348

COMPLETED Phase 3

Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer

NCT00027859

COMPLETED Phase 3

Gemcitabine With or Without Radiation Therapy in Treating Patients With Pancreatic Cancer

NCT00057876

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 87
Phase 3 37

What the Pipeline for Eastern Cooperative Oncology Group Shows

According to the ClinicalTrials.gov registry, Eastern Cooperative Oncology Group is linked to 141 US clinical trials across every stage of research activity. Of those, 4 studies are currently recruiting, about 3% of the sponsor's indexed portfolio, and 121 are already marked complete, representing roughly 86% of the total.

The phase mix for Eastern Cooperative Oncology Group reports 37 late-stage studies (Phase 3 and Phase 4 combined) and 90 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Eastern Cooperative Oncology Group is Bladder Cancer with 3 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.