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NCT05343598 · ClinicalTrials.gov registry record · NA
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
A NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Mclean Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 68
- Enrollment target
- 1
- Study location
NCT05343598: Recruiting NA study of Schizophrenia and Schizoaffective Disorder, sponsored by Mclean Hospital.
NCT05343598 is a NA study of Schizophrenia and Schizoaffective Disorder that is actively recruiting participants, run by Mclean Hospital. The registered enrollment target is 68 participants, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (69% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05343598, a NA study of Schizophrenia and Schizoaffective Disorder, is actively recruiting participants, sponsored by Mclean Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 68 participants
- Enrollment target
- 1
- Study location
Study Summary
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study the investigators will be stimulating the brain to learn more about how TMS might improve these symptoms of schizophrenia.
Primary Outcome
change in functional connectivity of a putative cerebellar-thalamic-cortical hallucination circuit (cerebellum to thalamus) will be assessed before and after (1 week followup) TMS stimulation.
Conditions Studied
Interventions
- DEVICE Repetitive Transcranial Magnetic Stimulation (rTMS)
- DEVICE Sham Repetitive Transcranial Magnetic Stimulation (rTMS)
Study Locations (1)
Massachusetts
- McLean Hospital - Belmont
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2021-10-13 |
| Est. Completion | 2026-10-31 |
| Phase | NA |
What NCT05343598 shows while recruiting
NCT05343598 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 219-participant average among 315 other Schizophrenia trials with a reported enrollment target (69% lower).
The record links to 2 conditions, with Schizophrenia appearing as the primary indexed condition, and to 2 interventions - of which Repetitive Transcranial Magnetic Stimulation (rTMS) is the first listed.
NCT05343598 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05343598 about?
NCT05343598 is a clinical study titled "Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia". This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held ...
What is the current status of trial NCT05343598?
This trial is currently recruiting. It is a NA study. The enrollment target is 68 participants. The study started on 2021-10-13. Estimated completion is 2026-10-31.
What conditions does trial NCT05343598 study?
This clinical trial studies the following conditions: Schizophrenia, Schizoaffective Disorder.
What interventions are being tested in trial NCT05343598?
The interventions under investigation include: Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE), Sham Repetitive Transcranial Magnetic Stimulation (rTMS) (DEVICE).
Who is sponsoring clinical trial NCT05343598?
This trial is sponsored by Mclean Hospital, which has 140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05343598 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Schizophrenia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05343598's enrollment target sits among peer trials
68 180th of 315 higher than 135 of 315 other Schizophrenia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Schizophrenia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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