Barbara Ann Karmanos Cancer Institute

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Barbara Ann Karmanos Cancer Institute sits in the top decile of US sponsors by registered trial count (#202 of 15,742 sponsors by registered trial count).

139 total trials 16 currently recruiting 100 completed early-phase tilt top decile by trial count

Barbara Ann Karmanos Cancer Institute: 139 sponsored US clinical trials, 16 recruiting.

Barbara Ann Karmanos Cancer Institute sponsors 139 registered US clinical trials on ClinicalTrials.gov, 16 of them currently recruiting, and 100 completed. 1 of these trials are in Phase 3-4 (later-stage) and 99 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Prostate Cancer, with 4 trials.

Top-decile sponsor footprint

Barbara Ann Karmanos Cancer Institute ranks in the top decile of sponsors by registered trial count (#202 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

100 of 120 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

139 total, page 1 of 3

RECRUITING NA

A Study of the TheraBionic P1 Device in Breast Cancer

NCT07218432

RECRUITING NA

Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors

NCT07436078

RECRUITING NA

TheraBionic P1 Device in Subjects With Advanced Hepatocellular Carcinoma

NCT07118202

RECRUITING Phase 1

Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies

NCT07098299

RECRUITING Phase 2

Amplitude-Modulated Radiofrequency Electromagnetic Fields (AM RF EMF) in Combination With Fruquintinib in Refractory Metastatic Colorectal Cancer

NCT07130903

RECRUITING NA

A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients.

NCT07095114

RECRUITING Phase 2

Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer

NCT06576115

RECRUITING NA

Addressing Social Determinants of Health Among Metro Detroit Cancer Survivors

NCT06908629

RECRUITING Phase 2

DapagliFLOzin in Renal AL Amyloidosis (FLORAL)

NCT06420167

RECRUITING Phase 2

Iberdomide and Daratumumab As Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma

NCT06107738

RECRUITING NA

Dietary Reporting in the Amyloidoses

NCT05738005

RECRUITING NA

A Provider Intervention to Reduce Financial Toxicity in Patients With Cancer Through Improved Treatment Cost Discussions

NCT07042191

RECRUITING Phase 1

F-Tryptophan PET/CT in Human Cancers

NCT05556473

RECRUITING NA

C.A.P.A.B.L.E. (CrossFit® and Physical Activity: A Better Life Experience)

NCT03750981

RECRUITING NA

Comprehensive Genomic Analysis in Tissue Samples From Patients With Recurrent or Stage IV Non-small Cell Lung Cancer

NCT02178163

RECRUITING

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

NCT00935090

ACTIVE NOT RECRUITING Phase 2

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma

NCT04479267

ACTIVE NOT RECRUITING Phase 1

Selinexor Plus Combination Chemotherapy in Treating Patients With Advanced B Cell Non-Hodgkin Lymphoma

NCT03147885

NOT YET RECRUITING NA

Study of the TheraBionic P1 Device in Patients With Metastatic Triple Negative Breast Cancer After Progression

NCT07672431

COMPLETED NA

Ask Questions (ASQ):Implementation of a Communication Intervention

NCT05025748

COMPLETED Phase 2

COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies

NCT05028374

TERMINATED Phase 1

Partial Brain RT, Temozolomide, Chloroquine, and TTF Therapy for the Treatment of Newly Diagnosed Glioblastoma

NCT04397679

COMPLETED NA

DISCO Application for the Improvement of Financial Outcomes in Patients With Hematologic Cancer

NCT04282343

COMPLETED NA

Medical Physics Direct Patient Care for the Improvement of Patient Understanding of Care

NCT04266522

TERMINATED Phase 2

ESK981 and Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer

NCT04159896

COMPLETED NA

Reducing Metabolic Syndrome Among Breast Cancer Survivors

NCT03719677

COMPLETED NA

Tobacco Cessation Intervention

NCT03657511

COMPLETED NA

Feasibility and Utilization of an Application-based Question Prompt List

NCT03676920

COMPLETED Phase 2

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

NCT03453489

COMPLETED Phase 2

Pembro and HER2Bi-Armed Activated T Cells in Treating Patients With Metastatic Castration Resistant Prostate Cancer

NCT03406858

COMPLETED Phase 2

Nivolumab and RT in Treating Patients With Localized/Locally Advanced Urothelial Bladder Cancer Ineligible for Chemo

NCT03421652

COMPLETED Phase 2

ESK981 in Treating Patients With Metastatic Castrate-Resistant Prostate Cancer

NCT03456804

COMPLETED NA

Music in Reducing Distress in Participants with Cancer During Chemotherapy Treatment

NCT03683420

COMPLETED NA

Dexamethasone Effects in Patients With Refractory Non-Small Cell Lung Cancer Using FLT Positron Emission Tomography

NCT02819024

COMPLETED Phase 2

Ibrutinib in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma

NCT02824029

COMPLETED Phase 2

Nintedanib in Treating Patients With Malignant Pleural Mesothelioma That Is Recurrent

NCT02568449

COMPLETED NA

Low-Level Laser Therapy for Prevention of Oral Mucositis

NCT02723604

COMPLETED Phase 1

BATS With in Combination With Low Dose IL-1 and GM-CSF for Advanced Pancreatic Cancer

NCT02620865

COMPLETED Phase 1

Folate Receptor in Diagnosing Ovarian Cancer Using Serum Samples From Patients With Newly Diagnosed Pelvic Mass or Previously Diagnosed Ovarian Cancer

NCT02520115

COMPLETED Phase 1

PLX3397, Radiation Therapy, and Antihormone Therapy in Treating Patients With Intermediate- or High-Risk Prostate Cancer

NCT02472275

TERMINATED Phase 1

Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphoma

NCT01609816

COMPLETED Phase 2

MK-3475 as Maintenance Therapy in Extensive Stage SCLC

NCT02359019

COMPLETED Phase 1

Radiation Therapy, Chemotherapy, and Soy Isoflavones in Treating Patients With Stage IIIA-IIIB Non-Small Cell Lung Cancer

NCT01958372

TERMINATED NA

Gene Expression Levels in Predicting Treatment Response in Patients With Stage IV Non-small Cell Lung Cancer

NCT02145078

COMPLETED Phase 2

LHRH Analogue Therapy With Enzalutamide or Bicalutamide in Treating Patients With Hormone Sensitive Prostate Cancer

NCT02058706

TERMINATED Phase 3

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

NCT01987596

COMPLETED NA

Cabozantinib-S-Malate in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer

NCT01812668

TERMINATED Phase 1

First-line Pomalidomide, Bortezomib, and Dexamethasone For AL Amyloidosis or LCDD

NCT01728259

COMPLETED NA

Ultrasound Tomography Using SoftVue in Diagnosing Women With Breast Cancer

NCT01698658

TERMINATED Phase 1

Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies

NCT01643603

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What is open in the Barbara Ann Karmanos Cancer Institute pipeline

16 recruiting of 139 indexed (12% open); 100 completed (72%).

Phase mix: 1 late (III/IV) vs 99 early (I/II) (early-phase heavy).

Top condition: Prostate Cancer (4 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Barbara Ann Karmanos Cancer Institute: open-pipeline peers nationwide

Peers matched on 139 registered trials and 12% open enrollment, not the therapeutic-area sidebar.

Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 050100150 0%10%20%30% Total trials Recruiting share Barbara Ann Karmanos Cancer InstituteCenters for Disease Control and PreventionMclean HospitalShirley Ryan AbilityLabSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson UniversityAbbott Diabetes CareMedtronic VascularMidwest Center for Metabolic and Cardiovascular ResearchVA Connecticut Healthcare System
Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Barbara Ann Karmanos Cancer Institute sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 139 trials (± recruiting share)

Sponsors near 12% open enrollment (± trial volume)

What to do with this Barbara Ann Karmanos Cancer Institute page

139 registered trials is a research-attention snapshot, not an endorsement of Barbara Ann Karmanos Cancer Institute or any single study.

  • 16 of Barbara Ann Karmanos Cancer Institute's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Prostate Cancer is the condition Barbara Ann Karmanos Cancer Institute studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Prostate Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Barbara Ann Karmanos Cancer Institute pipeline card: 139 registered trials from official public datasets.Report a data error.