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Pneumonia: early-phase trial registry
17 of 48 indexed Pneumonia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #297 of 28,707 conditions by registered trial count.
48 US clinical trials · 17 currently recruiting · #297 of 28,707 conditions by registered trial count
Pneumonia: 48 US clinical trials tracked, 17 recruiting.
Pneumonia is the subject of 48 registered US clinical trials on ClinicalTrials.gov, 17 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Institute of Allergy and Infectious Diseases (NIAID), running 3 of these trials.
Enrollment posture brief
Registry condition pneumonia
OPEN 17 | RECR 35% | LATE 4 | EARLY 15 | RANK #297 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Squamous Cell Carcinoma (35% recruiting · 48 trials)
Pneumonia lists 17 open slots (35% of 48 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pneumonia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pneumonia is recruiting below its size-band peers.
17 of 48 indexed trials (35.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Pneumonia trials is spread across many organizations.
National Institute of Allergy and Infectious Diseases (NIAID) accounts for 3 of 48 trials (6.3%). 38 distinct sponsors appear on at least one study for this condition label.
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Typical Pneumonia enrolment sits around 168 participants.
Median target enrolment is 168 among the 48 trials that report a genuine target (sentinel values excluded). 19 of those (39.6%) plan for fewer than 100 participants.
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Pneumonia research is mostly interventional.
36 interventional and 12 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
48 total, page 1 of 1
A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
Pfizer
NCT05452941
The APS Phenotyping Study
Vanderbilt University Medical Center
NCT06521502
Adaptation and Pilot Implementation of ePNa Clinical Decision Support for Utah Urgent Care Clinics
Intermountain Health Care
NCT04606849
Reducing Overuse of Antibiotics With Decision Support
Vanderbilt University Medical Center
NCT06788093
Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial
University of Utah
NCT05471908
Study of Lung Proteins in Patients With Pneumonia
National Institutes of Health Clinical Center (CC)
NCT00077909
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00006150
Performance of New Diagnostic Methods in Older Adults With Pneumonia
Ohio State University
NCT06092008
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Brigham and Women's Hospital
NCT06538376
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
Missouri Department of Health and Senior Services
NCT06890676
The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
Washington University School of Medicine
NCT03482245
Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.
Vasomune Therapeutics
NCT05123755
How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.
Geisinger Clinic
NCT06495021
PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity
Boston Children's Hospital
NCT06364514
iNO300 Therapy in Critically Ill Patients With Pneumonia
Massachusetts General Hospital
NCT06950294
Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
M.D. Anderson Cancer Center
NCT05041140
Individualizing Corticosteroid Use in Pneumonia
Mayo Clinic
NCT05334316
LungVITamin D and OmegA-3 Trial (lungVITAL)
Brigham and Women's Hospital
NCT01728571
Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children
University of California, San Francisco
NCT05206695
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
University of California, Los Angeles
NCT06526884
Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia
Ohio State University Comprehensive Cancer Center
NCT04466683
Dissemination and Implementation of a Videoconference Antimicrobial Stewardship Team
VA Office of Research and Development
NCT05319561
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Massachusetts General Hospital
NCT02105298
The INSPIRE-ASP PNA Trial
Harvard Pilgrim Health Care
NCT03697070
An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03908632
Multicenter Infection Surveillance Study Following Open Heart Surgery
Halyard Health
NCT00673712
Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia
Advanced Life Sciences
NCT00336544
Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support
Pfizer
NCT00050401
A Study of Auxora in Patients With Severe COVID-19 Pneumonia
CalciMedica
NCT04345614
Pneumococcal Adult-dose Ranging Immunization Study
Kaiser Permanente
NCT00169234
Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections
Cook County Health
NCT00130221
Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With Pneumonia
Corewell Health South
NCT03711227
Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients
State University of New York at Buffalo
NCT00123123
Evidence Based Decision Making: Integrating Clinical Prediction Rules
Northwell Health
NCT01386047
A Peri-intubation Oral Intervention to Reduce Oral Flora and VAP
Virginia Commonwealth University
NCT00248300
Reducing Length of Stay for Veterans Hospitalized With Pneumonia
VA Office of Research and Development
NCT01068548
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Community Acquired Pneumonia in Older Adults
University of Wisconsin, Madison
NCT04709978
Association of Transcutaneous Pulse CO-oximetry With Inflammatory Lung Diseases
Boston Children's Hospital
NCT02831348
A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271
Tetraphase Pharmaceuticals
NCT02724085
Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia
Mayo Clinic
NCT03852537
Integrated Clinical Prediction Rules: Bringing Evidence to Diverse Primary Care Settings
NYU Langone Health
NCT02534987
Clinician Ability to Predict the Presence of Nosocomial Pneumonia Based on Bronchoscopic Findings
University of Cincinnati
NCT01904305
Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia
Bayer
NCT01021436
Interferon Gamma for Drug Resistant Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001407
Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia
University of Virginia
NCT04374565
PET Imaging of Endotoxin-induced iNOS Activation
Washington University School of Medicine
NCT01407796
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
Ann & Robert H Lurie Children's Hospital of Chicago
NCT04963764
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Pneumonia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pneumonia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pneumonia page
48 registered trials, 17 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 17 Pneumonia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Institute of Allergy and Infectious Diseases (NIAID) sponsors the most Pneumonia trials on record, review their full trial history before evaluating a specific study. See National Institute of Allergy and Infectious Diseases (NIAID)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pneumonia condition card totals 48 registered trials; most-linked intervention [18F](+/-)NOS; top US site state Ohio. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.