Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Pneumonia
Open-data reference.
48 US clinical trials · 17 currently recruiting
Active & Recent Trials
A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
Pfizer
NCT05452941
The APS Phenotyping Study
Vanderbilt University Medical Center
NCT06521502
Adaptation and Pilot Implementation of ePNa Clinical Decision Support for Utah Urgent Care Clinics
Intermountain Health Care
NCT04606849
Reducing Overuse of Antibiotics With Decision Support
Vanderbilt University Medical Center
NCT06788093
Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial
University of Utah
NCT05471908
Study of Lung Proteins in Patients With Pneumonia
National Institutes of Health Clinical Center (CC)
NCT00077909
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00006150
Performance of New Diagnostic Methods in Older Adults With Pneumonia
Ohio State University
NCT06092008
Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU
Brigham and Women's Hospital
NCT06538376
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
Missouri Department of Health and Senior Services
NCT06890676
The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
Washington University School of Medicine
NCT03482245
Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.
Vasomune Therapeutics
NCT05123755
How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.
Geisinger Clinic
NCT06495021
PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity
Boston Children's Hospital
NCT06364514
iNO300 Therapy in Critically Ill Patients With Pneumonia
Massachusetts General Hospital
NCT06950294
Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
M.D. Anderson Cancer Center
NCT05041140
Individualizing Corticosteroid Use in Pneumonia
Mayo Clinic
NCT05334316
LungVITamin D and OmegA-3 Trial (lungVITAL)
Brigham and Women's Hospital
NCT01728571
Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children
University of California, San Francis
NCT05206695
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
University of California, Los Angeles
NCT06526884
Low-Dose Radiotherapy For Patients With SARS-COV-2 (COVID-19) Pneumonia
Ohio State University Comprehensive Cancer Center
NCT04466683
Dissemination and Implementation of a Videoconference Antimicrobial Stewardship Team
VA Office of Research and Development
NCT05319561
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Massachusetts General Hospital
NCT02105298
The INSPIRE-ASP PNA Trial
Harvard Pilgrim Health Care
NCT03697070
An Observational Study to Assess the Prevalence and Outcomes of Primary Pulmonary Coccidioidomycosis in Persons Aged > / = 14 Years Presenting With Community Acquired Pneumonia (CAP) in Endemic Areas (SAnds-PPC)
National Institute of Allergy and Infectious Diseases (NIAID)
NCT03908632
Multicenter Infection Surveillance Study Following Open Heart Surgery
Halyard Health
NCT00673712
Study Comparing the Safety and Efficacy of Cethromycin to Clarithromycin for the Treatment of Community-Acquired Pneumonia
Advanced Life Sciences
NCT00336544
Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support
Pfizer
NCT00050401
A Study of Auxora in Patients With Severe COVID-19 Pneumonia
CalciMedica
NCT04345614
Pneumococcal Adult-dose Ranging Immunization Study
Kaiser Permanente
NCT00169234
Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections
Cook County Health
NCT00130221
Procalcitonin at Zero and 24 Hours as a Prognostic Factor in Patients With Pneumonia
Corewell Health South
NCT03711227
Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients
State University of New York at Buffalo
NCT00123123
Evidence Based Decision Making: Integrating Clinical Prediction Rules
Northwell Health
NCT01386047
A Peri-intubation Oral Intervention to Reduce Oral Flora and VAP
Virginia Commonwealth University
NCT00248300
Reducing Length of Stay for Veterans Hospitalized With Pneumonia
VA Office of Research and Development
NCT01068548
Specialized Community Disease Management to Reduce Substance Use and Hospital Readmissions
Treatment Research Institute
NCT02059005
Community Acquired Pneumonia in Older Adults
University of Wisconsin, Madison
NCT04709978
Association of Transcutaneous Pulse CO-oximetry With Inflammatory Lung Diseases
Boston Children's Hospital
NCT02831348
A Phase 1 Study to Assess the Safety, Tolerability and PK of IV TP-271
Tetraphase Pharmaceuticals
NCT02724085
Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia
Mayo Clinic
NCT03852537
Integrated Clinical Prediction Rules: Bringing Evidence to Diverse Primary Care Settings
NYU Langone Health
NCT02534987
Clinician Ability to Predict the Presence of Nosocomial Pneumonia Based on Bronchoscopic Findings
University of Cincinnati
NCT01904305
Safety, Tolerability and Pharmacokinetics of Aerosolized Amikacin in Intubated and Mechanically-ventilated Patients With Nosocomial Pneumonia
Bayer
NCT01021436
Interferon Gamma for Drug Resistant Tuberculosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00001407
Convalescent Plasma for Treatment of COVID-19 Patients With Pneumonia
University of Virginia
NCT04374565
PET Imaging of Endotoxin-induced iNOS Activation
Washington University School of Medicine
NCT01407796
Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia
Ann & Robert H Lurie Children's Hospital of Chicago
NCT04963764
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 6 |
| Phase 2 | 9 |
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Pneumonia Trial Landscape
ClinicalTrials.gov lists 48 US studies indexed under Pneumonia, and 17 of those are currently open to recruitment — roughly 35% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Pneumonia shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Pneumonia is led by National Institute of Allergy and Infectious Diseases (NIAID) with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 48 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Pneumonia?
PlainTrial tracks 48 US clinical trials for Pneumonia, of which 17 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Pneumonia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.