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NCT00123123 · ClinicalTrials.gov registry record · Phase 2

Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients

A Phase 2 study of Pneumonia, sponsored by State University of New York at Buffalo.

Completed
Registry status
Phase 2
Development phase
175
Enrollment target
1
Study location

NCT00123123 is a Phase 2 study of Pneumonia that has completed, run by State University of New York at Buffalo. The registered enrollment target is 175 participants, below the 4,516-participant average among 47 other Pneumonia trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00123123, a Phase 2 study of Pneumonia, has completed, sponsored by State University of New York at Buffalo.

COMPLETED
Registry status
Phase 2
Development phase
175 participants
Enrollment target
1
Study location

Study Summary

Recent studies have found that poor oral hygiene may foster the colonization of the oropharynx by potential respiratory pathogens in mechanically-ventilated (MV), intensive care unit (ICU) patients. Thus, improvements in oral hygiene in MV-ICU patients may prevent ventilator-associated pneumonia (VAP). The specific aims of this investigation are: 1) to organize the necessary infrastructure to develop and perform a pilot clinical trial to evaluate alternative oral hygiene procedures to prevent VAP; 2) to use this organization to perform a pilot clinical trial to determine if the use of oral topical chlorhexidine gluconate (CHX) will prevent dental plaque, oropharyngeal colonization by respiratory pathogens, and VAP in MV-ICU patients.

Conditions Studied

Interventions

  • DRUG placebo
  • DRUG chlorhexidine gluconate oral rinse (0.12%)

Study Locations (1)

New York

  • University of Buffalo, The State University of New York - Buffalo

Trial Details

FieldValue
Enrollment Target 175 participants
Start Date 2004-03
Est. Completion 2007-11
Phase Phase 2

What the Registry Record Tells You About NCT00123123

The ClinicalTrials.gov registry entry for NCT00123123 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 175 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,516-participant average among 47 other Pneumonia trials with a reported enrollment target (96% lower). The listed sponsor is State University of New York at Buffalo, which has 243 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.

NCT00123123 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT00123123 about?

NCT00123123 is a clinical study titled "Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients". Recent studies have found that poor oral hygiene may foster the colonization of the oropharynx by potential respiratory pathogens in mechanically-ventilated (MV), intensive care unit (ICU) patients. Thus, improvements in oral hygiene in MV-ICU patients may prevent ventilator-associated pneumonia (VA...

What is the current status of trial NCT00123123?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 175 participants. The study started on 2004-03. Estimated completion is 2007-11.

What conditions does trial NCT00123123 study?

This clinical trial studies the following conditions: Pneumonia.

What interventions are being tested in trial NCT00123123?

The interventions under investigation include: placebo (DRUG), chlorhexidine gluconate oral rinse (0.12%) (DRUG).

Who is sponsoring clinical trial NCT00123123?

This trial is sponsored by State University of New York at Buffalo, which has 243 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00123123 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.