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NCT02105298 · ClinicalTrials.gov registry record
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
A clinical trial of Acute Kidney Injury and Pneumonia, sponsored by Massachusetts General Hospital.
- Completed
- Registry status
- 104,000
- Enrollment target
- 1
- Study location
NCT02105298: Completed study of Acute Kidney Injury and Pneumonia, sponsored by Massachusetts General Hospital.
NCT02105298 is a study of Acute Kidney Injury and Pneumonia that has completed, run by Massachusetts General Hospital. The registered enrollment target is 104,000 participants, above the 926-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (11131% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02105298, a study of Acute Kidney Injury and Pneumonia, has completed, sponsored by Massachusetts General Hospital.
- COMPLETED
- Registry status
- 104,000 participants
- Enrollment target
- 1
- Study location
Study Summary
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity. Postoperative respiratory complications are associated with increased morbidity, mortality and hospital costs. The literature shows conflicting data regarding intraoperative fluid resuscitation volume. No large-scale studies have focused on intraoperative fluid management and postoperative respiratory dysfunction. Hypotheses: Primary - Liberal intraoperative fluid resuscitation is associated with an increased risk of 30 day mortality Secondary - Liberal intraoperative fluid resuscitation is associated with increased likelihood of postoperative respiratory failure, pulmonary edema, reintubation, atelectasis, acute kidney injury and peri-extubation oxygen desaturation.
Primary Outcome
Mortality within 30 days of surgery
Conditions Studied
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 104,000 participants |
| Start Date | 2013-09 |
| Est. Completion | 2014-03 |
What the finished NCT02105298 record still lists
NCT02105298 is an observational study that tracks outcomes without assigning an intervention. Its 104,000 participants enrollment target places it among the larger protocols in the corpus, above the 926-participant average among 74 other Acute Kidney Injury trials with a reported enrollment target (11131% higher).
The record links to 6 conditions, with Acute Kidney Injury appearing as the primary indexed condition, and to 0 interventions.
NCT02105298 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02105298 about?
NCT02105298 is a clinical study titled "Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)". Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity. Postoperative respiratory complications are associated with increased morbidity, mortality and hospital costs. The literature shows...
What is the current status of trial NCT02105298?
This trial is currently completed. The enrollment target is 104,000 participants. The study started on 2013-09. Estimated completion is 2014-03.
What conditions does trial NCT02105298 study?
This clinical trial studies the following conditions: Acute Kidney Injury, Pneumonia, Respiratory Failure, Hypoxia, Pulmonary Edema.
Who is sponsoring clinical trial NCT02105298?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02105298 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02105298's enrollment target sits among peer trials
104,000 1st of 74 higher than 74 of 74 other Acute Kidney Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Kidney Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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