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NCT04963764 · ClinicalTrials.gov registry record · Early Phase 1

Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia

A Early Phase 1 study of Pneumonia and Community-acquired Pneumonia, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

Completed
Registry status
Early Phase 1
Development phase
5
Enrollment target
3
Study locations

NCT04963764 is a Early Phase 1 study of Pneumonia and Community-acquired Pneumonia that has completed, run by Ann & Robert H Lurie Children's Hospital of Chicago. The registered enrollment target is 5 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT04963764, a Early Phase 1 study of Pneumonia and Community-acquired Pneumonia, has completed, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

COMPLETED
Registry status
Early Phase 1
Development phase
5 participants
Enrollment target
3
Study locations

Study Summary

This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and procalcitonin (PCT) levels \<0.25 ng/mL treated with placebo have a similar clinical response to those treated with antibiotics and fewer adverse effects.

Interventions

  • DRUG Placebo
  • DRUG Amoxicillin

Study Locations (3)

Illinois

  • Ann & Robert H Lurie Children's Hospital of Chicago - Chicago

Ohio

  • Cincinnati Children's Hospital Medical Center - Cincinnati

Pennsylvania

  • The Children's Hospital of Philadelphia - Philadelphia

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2021-10-18
Est. Completion 2022-05-27
Phase Early Phase 1

What the Registry Record Tells You About NCT04963764

The ClinicalTrials.gov registry entry for NCT04963764 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 5 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower). The listed sponsor is Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04963764 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Illinois, Ohio, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04963764 about?

NCT04963764 is a clinical study titled "Procalcitonin to Reduce Antibiotic Use in Pediatric Pneumonia". This pilot study will evaluate study processes and feasibility of a future large-scale clinical trial that proposes to test whether low-risk children managed as outpatients with community-acquired pneumonia (CAP) and procalcitonin (PCT) levels \<0.25 ng/mL treated with placebo have a similar clinica...

What is the current status of trial NCT04963764?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2021-10-18. Estimated completion is 2022-05-27.

What conditions does trial NCT04963764 study?

This clinical trial studies the following conditions: Pneumonia, Community-acquired Pneumonia, Pediatric Respiratory Diseases, Antibiotic Use.

What interventions are being tested in trial NCT04963764?

The interventions under investigation include: Placebo (DRUG), Amoxicillin (DRUG).

Who is sponsoring clinical trial NCT04963764?

This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04963764 being conducted?

This trial has 3 study locations across Illinois, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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