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NCT03852537 · ClinicalTrials.gov registry record · Phase 2

Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia

A Phase 2 study of Pneumonia, sponsored by Mayo Clinic.

Completed
Registry status
Phase 2
Development phase
44
Enrollment target
1
Study location

NCT03852537 is a Phase 2 study of Pneumonia that has completed, run by Mayo Clinic. The registered enrollment target is 44 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03852537, a Phase 2 study of Pneumonia, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
Phase 2
Development phase
44 participants
Enrollment target
1
Study location

Study Summary

This research study is being done to determine the appropriate dose of steroids and the appropriate duration for steroid use to reduce inflammation in severe pneumonia needing a form of breathing support. This study seeks to compare usual care to a unique (individualized) dosing strategy. A marker of inflammation in the body will be measured in blood samples. This marker of inflammation is called C- reactive protein. The overall goal is to identify patients that will benefit most from steroid use and decrease use of steroids. The information collected from this study may provide information that may improve management of patients with severe pneumonia requiring a form of breathing support.

Conditions Studied

Interventions

  • OTHER Usual Care
  • DRUG Methylprednisolone

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2019-12-02
Est. Completion 2020-11-17
Phase Phase 2

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT03852537

The ClinicalTrials.gov registry entry for NCT03852537 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.

NCT03852537 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT03852537 about?

NCT03852537 is a clinical study titled "Steroid Dosing by bioMARker Guided Titration in Critically Ill Patients With Pneumonia". This research study is being done to determine the appropriate dose of steroids and the appropriate duration for steroid use to reduce inflammation in severe pneumonia needing a form of breathing support. This study seeks to compare usual care to a unique (individualized) dosing strategy. A marker o...

What is the current status of trial NCT03852537?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2019-12-02. Estimated completion is 2020-11-17.

What conditions does trial NCT03852537 study?

This clinical trial studies the following conditions: Pneumonia.

What interventions are being tested in trial NCT03852537?

The interventions under investigation include: Usual Care (OTHER), Methylprednisolone (DRUG).

Who is sponsoring clinical trial NCT03852537?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03852537 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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