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NCT01407796 · ClinicalTrials.gov registry record · Phase 1
PET Imaging of Endotoxin-induced iNOS Activation
A Phase 1 study of Pneumonia, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT01407796: Completed Phase 1 study of Pneumonia, sponsored by Washington University School of Medicine.
NCT01407796 is a Phase 1 study of Pneumonia that has completed, run by Washington University School of Medicine. The registered enrollment target is 19 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01407796, a Phase 1 study of Pneumonia, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall purpose of this research is to gain understanding of the basic responses of the lung to inflammation. Inflammation is the way our bodies react to irritation or injury, and involves red, warm, and often painful swelling of the affected tissue. "Acute lung injury" involves a generalized inflammation to the lung that is activated by any of several conditions: infection, trauma, inhalation of toxic substances, etc. When lung injury is severe, not enough oxygen can get into the body; this can lead to the need for mechanical support of breathing (mechanical ventilation), problems with brain, heart or other organ function, and in some cases, death. Inducible nitric oxide synthase (iNOS) contributes to the development of lung inflammation.
Conditions Studied
Interventions
- DRUG Endotoxin (E. coli O:113, Reference Endotoxin)
- DRUG [18F](+/-)NOS
Study Locations (1)
Missouri
- Washington University School of Medicne - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2010-12 |
| Est. Completion | 2012-04 |
| Phase | Phase 1 |
What the finished NCT01407796 record still lists
NCT01407796 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which Endotoxin (E. coli O:113, Reference Endotoxin) is the first listed.
NCT01407796 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT01407796 about?
NCT01407796 is a clinical study titled "PET Imaging of Endotoxin-induced iNOS Activation". The overall purpose of this research is to gain understanding of the basic responses of the lung to inflammation. Inflammation is the way our bodies react to irritation or injury, and involves red, warm, and often painful swelling of the affected tissue. "Acute lung injury" involves a generalized in...
What is the current status of trial NCT01407796?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2010-12. Estimated completion is 2012-04.
What conditions does trial NCT01407796 study?
This clinical trial studies the following conditions: Pneumonia.
What interventions are being tested in trial NCT01407796?
The interventions under investigation include: Endotoxin (E. coli O:113, Reference Endotoxin) (DRUG), [18F](+/-)NOS (DRUG).
Who is sponsoring clinical trial NCT01407796?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01407796 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01407796's enrollment target sits among peer trials
19 46th of 47 higher than 2 of 47 other Pneumonia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pneumonia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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