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NCT01407796 · ClinicalTrials.gov registry record · Phase 1
PET Imaging of Endotoxin-induced iNOS Activation
A Phase 1 study of Pneumonia, sponsored by Washington University School of Medicine.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
- 1
- Study location
NCT01407796 is a Phase 1 study of Pneumonia that has completed, run by Washington University School of Medicine. The registered enrollment target is 19 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01407796, a Phase 1 study of Pneumonia, has completed, sponsored by Washington University School of Medicine.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
- 1
- Study location
Study Summary
The overall purpose of this research is to gain understanding of the basic responses of the lung to inflammation. Inflammation is the way our bodies react to irritation or injury, and involves red, warm, and often painful swelling of the affected tissue. "Acute lung injury" involves a generalized inflammation to the lung that is activated by any of several conditions: infection, trauma, inhalation of toxic substances, etc. When lung injury is severe, not enough oxygen can get into the body; this can lead to the need for mechanical support of breathing (mechanical ventilation), problems with brain, heart or other organ function, and in some cases, death. Inducible nitric oxide synthase (iNOS) contributes to the development of lung inflammation.
Conditions Studied
Interventions
- DRUG Endotoxin (E. coli O:113, Reference Endotoxin)
- DRUG [18F](+/-)NOS
Study Locations (1)
Missouri
- Washington University School of Medicne - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2010-12 |
| Est. Completion | 2012-04 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01407796
The ClinicalTrials.gov registry entry for NCT01407796 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 19 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (100% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pneumonia appearing as the primary indexed condition, and to 2 interventions - of which Endotoxin (E. coli O:113, Reference Endotoxin) is the first listed.
NCT01407796 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.
Frequently Asked Questions
What is clinical trial NCT01407796 about?
NCT01407796 is a clinical study titled "PET Imaging of Endotoxin-induced iNOS Activation". The overall purpose of this research is to gain understanding of the basic responses of the lung to inflammation. Inflammation is the way our bodies react to irritation or injury, and involves red, warm, and often painful swelling of the affected tissue. "Acute lung injury" involves a generalized in...
What is the current status of trial NCT01407796?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2010-12. Estimated completion is 2012-04.
What conditions does trial NCT01407796 study?
This clinical trial studies the following conditions: Pneumonia.
What interventions are being tested in trial NCT01407796?
The interventions under investigation include: Endotoxin (E. coli O:113, Reference Endotoxin) (DRUG), [18F](+/-)NOS (DRUG).
Who is sponsoring clinical trial NCT01407796?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01407796 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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