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NCT05041140 · ClinicalTrials.gov registry record

Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

A clinical trial of Pneumonia and Hematopoietic System--Cancer, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
25
Enrollment target
1
Study location

NCT05041140 is a study of Pneumonia and Hematopoietic System--Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 25 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05041140, a study of Pneumonia and Hematopoietic System--Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
25 participants
Enrollment target
1
Study location

Study Summary

This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impairment not meeting the definition for BOS, defined below) and controls with chronic graft-versus-host disease (cGVHD). The primary objective of the study is to correlate 129-Xenon measures of ventilation, gas exchange, and pulmonary circulation with spirometric and quantitative CT measurements. A secondary objective is to determine whether measurement of 129-Xe MRI characteristics in patients with BOS stage 0p can predict BOS progression 6 months after enrollment.

Interventions

  • DEVICE 29-XeMRI imaging

Study Locations (1)

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2024-08-14
Est. Completion 2027-07-20

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT05041140

The ClinicalTrials.gov registry entry for NCT05041140 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Pneumonia appearing as the primary indexed condition, and to 1 intervention - of which 29-XeMRI imaging is the first listed.

NCT05041140 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05041140 about?

NCT05041140 is a clinical study titled "Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment". This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impa...

What is the current status of trial NCT05041140?

This trial is currently recruiting. The enrollment target is 25 participants. The study started on 2024-08-14. Estimated completion is 2027-07-20.

What conditions does trial NCT05041140 study?

This clinical trial studies the following conditions: Pneumonia, Hematopoietic System--Cancer, Pulmonary.

What interventions are being tested in trial NCT05041140?

The interventions under investigation include: 29-XeMRI imaging (DEVICE).

Who is sponsoring clinical trial NCT05041140?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05041140 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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