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NCT05041140 · ClinicalTrials.gov registry record
Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
A clinical trial of Pneumonia and Hematopoietic System--Cancer, sponsored by M.D. Anderson Cancer Center.
- Recruiting
- Registry status
- 25
- Enrollment target
- 1
- Study location
NCT05041140: Recruiting study of Pneumonia and Hematopoietic System--Cancer, sponsored by M.D. Anderson Cancer Center.
NCT05041140 is a study of Pneumonia and Hematopoietic System--Cancer that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 25 participants, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05041140, a study of Pneumonia and Hematopoietic System--Cancer, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.
- RECRUITING
- Registry status
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impairment not meeting the definition for BOS, defined below) and controls with chronic graft-versus-host disease (cGVHD). The primary objective of the study is to correlate 129-Xenon measures of ventilation, gas exchange, and pulmonary circulation with spirometric and quantitative CT measurements. A secondary objective is to determine whether measurement of 129-Xe MRI characteristics in patients with BOS stage 0p can predict BOS progression 6 months after enrollment.
Conditions Studied
Interventions
- DEVICE 29-XeMRI imaging
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2024-08-14 |
| Est. Completion | 2027-07-20 |
What NCT05041140 shows while recruiting
NCT05041140 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 4,519-participant average among 47 other Pneumonia trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Pneumonia appearing as the primary indexed condition, and to 1 intervention - of which 29-XeMRI imaging is the first listed.
NCT05041140 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05041140 about?
NCT05041140 is a clinical study titled "Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment". This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impa...
What is the current status of trial NCT05041140?
This trial is currently recruiting. The enrollment target is 25 participants. The study started on 2024-08-14. Estimated completion is 2027-07-20.
What conditions does trial NCT05041140 study?
This clinical trial studies the following conditions: Pneumonia, Hematopoietic System--Cancer, Pulmonary.
What interventions are being tested in trial NCT05041140?
The interventions under investigation include: 29-XeMRI imaging (DEVICE).
Who is sponsoring clinical trial NCT05041140?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05041140 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pneumonia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05041140's enrollment target sits among peer trials
25 44th of 47 higher than 4 of 47 other Pneumonia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pneumonia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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