Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Obesity: early-phase trial registry
306 of 1,057 indexed Obesity trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3 of 28,963 conditions by registered trial count.
1,057 US clinical trials · 306 currently recruiting · #3 of 28,963 conditions by registered trial count
Obesity: 1,057 US clinical trials tracked, 306 recruiting.
Obesity is the subject of 1,057 registered US clinical trials on ClinicalTrials.gov, 306 of them currently open to new participants. 107 are in Phase 3-4 (later-stage) and 196 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 48 of these trials.
Open enrollment, early-phase tilt
Obesity has 1,057 registered US clinical trials, 306 of them open to new participants right now, about 29% of the total.
- 306
- recruiting participants now
- 29%
- of trials open to enrollment
- 107
- in Phase 3-4 (later-stage)
- 48
- top sponsor: Eli Lilly and Company
Corpus placement: #3 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Obesity on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Obesity is recruiting below its size-band peers.
306 of 1,057 indexed trials (28.9%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Obesity trials is spread across many organizations.
Eli Lilly and Company accounts for 48 of 1,057 trials (4.5%). 314 distinct sponsors appear on at least one study for this condition label.
-
Typical Obesity enrolment sits around 90 participants.
Median target enrolment is 90 among the 1,054 trials that report a genuine target (sentinel values excluded). 555 of those (52.7%) plan for fewer than 100 participants.
-
Obesity research is mostly interventional.
894 interventional and 163 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
1,057 total, page 6 of 22
Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism
University of North Carolina, Chapel Hill
NCT04328337
FEAST Perinatal Support Program Intervention
University of Southern California
NCT06715787
Physiologic Response to Bariatric Surgery and the Impact of Adjunct Semaglutide in Adolescents
University of Colorado, Denver
NCT06575738
Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Therapy and Exercise Training in People With Obesity
Washington University School of Medicine
NCT07091500
The Physiology of Human Brown Adipose Tissue
Beth Israel Deaconess Medical Center
NCT04352244
Pharmacologic Weight Loss as Adjunct Therapy for Ulcerative Colitis in Obese Patients
University of California, San Diego
NCT04721873
Ketogenic Diet and Diabetes Demonstration Project
University of New Mexi
NCT06115265
Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.
University of North Carolina, Chapel Hill
NCT06991296
Dinner Time for Obesity and Prediabetes
Johns Hopkins University
NCT05745441
Redefining BMI: The Body, Mind, and Inflammation Trial
Virginia Commonwealth University
NCT06532747
Feasibility Study for the Comprehensive Overweight/Obesity Management Pre-Kidney Transplant (COMPKT) Program
Virginia Commonwealth University
NCT06688825
High Fructose Diet, the Gut Microbiome, and Metabolic Health
Icahn School of Medicine at Mount Sinai
NCT06329544
Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia
Dana-Farber Cancer Institute
NCT04839614
Efficacy of Using Mobile Health Applications for Health
San Diego State University
NCT05589155
Investigating the Effects of the "GameDay Ready" Behavioral Weight Management Program for Black Men Living in the Rural South
University of South Carolina
NCT05970042
Physical Activity: Feasibility Study
Binghamton University
NCT05935111
Growth Hormone Resistance of Beta-cells
University of Missouri-Columbia
NCT06571487
Growth Hormone Resistance of Beta-cells in Women and People
University of Missouri-Columbia
NCT06571500
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
University of Chicago
NCT06171152
Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure
Christopher C. Thompson, MD, MSc
NCT05711758
Respiratory Muscle Training to Improve Cerebrovascular and Immune Function
Florida State University
NCT07406295
WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time
Arizona State University
NCT06963736
EBT Fruit and Vegetable Prescription
The University of Tennessee, Knoxville
NCT05028205
A Nutrition & Exercise Prehabilitation Intervention on Inflammatory Biomarkers in AI Cancer Patients
University of Arizona
NCT06644560
Metabolic Effects of Angiotensin-(1-7)
Vanderbilt University
NCT02646475
Role of Aging and Individual Variation in Exercise Training Responsiveness
Duke University
NCT06471569
Feasibility and Colorectal Benefits of Pulses Supplementation
University of California, Davis
NCT06032104
Microvascular Dysfunction in Obesity
Florida State University
NCT04087655
A Hip Flexion Feedback System for Exercise Monitoring in Individuals With Osteoarthritis and Obesity
University of Southern Mississippi
NCT05997862
Tai Chi as a Novel Strategy to Increase Physical Activity Among Adults Pursuing Metabolic and Bariatric Surgery
Hartford Hospital
NCT06445413
Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation
Mayo Clinic
NCT06416969
Brain Blood Flow and Lactate in Non-obese and Obese Subjects
University of Missouri-Columbia
NCT06791837
Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
University of Illinois at Chicago
NCT06504914
Convergent Mechanisms Underlying Reprometabolic Syndrome in Women
University of Colorado, Denver
NCT06686537
Medically Intensive Nutrition Therapy Program for Obesity and Diabetes in a Low-income Population
Massachusetts General Hospital
NCT05799222
Benefits of Endoscopic Bariatric Procedures
Cedars-Sinai Medical Center
NCT05514288
Brown Adipose Tissue Activity in Response to Semaglutide Administered to Obese Subjects.
University of California, Los Angeles
NCT05419726
Prospective Evaluation of Adjusted Body Weight Dosing of Acyclovir in Obesity
West Virginia University
NCT02879630
Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients
University of California, Los Angeles
NCT04997473
Sleep and Metabolism
Oregon Health and Science University
NCT05775627
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
Jonsson Comprehensive Cancer Center
NCT04453072
The Effects of Metabolic & Bariatric Surgery on Lipid Metabolism, Myeloid-Derived Suppressor Cells, and Cancer Cell Biology
Pennington Biomedical Research Center
NCT06059651
Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity
University of Alabama at Birmingham
NCT06736028
Development of a MHBC Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
Yale University
NCT07224087
Dietary Supplementation on Fat Oxidation
Brightseed
NCT06548048
Graded Insulin Suppression Test P&F
Columbia University
NCT06592261
Exercise, Brain Activity, and Weight Maintenance
Joslin Diabetes Center
NCT06511310
Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes
Yale University
NCT06105931
A Study of Endoscopic Sleeve Gastroplasty for Obesity in Ulcerative Colitis
Mayo Clinic
NCT05739162
Experimental Approach to Test Predictions of Body Weight Regulation Models
Pennington Biomedical Research Center
NCT06309576
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 95 |
| Phase 2 | 101 |
| Phase 3 | 69 |
| Phase 4 | 38 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Obesity right now
306 recruiting of 1,057 indexed (29% open).
Phase mix: 107 late (III/IV) vs 196 early (I/II) (early-phase heavy).
Top sponsor: Eli Lilly and Company (48 trials), 9 others listed. 50 shown below, recruiting first. #3 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Obesity?
PlainTrial tracks 1,057 US clinical trials for Obesity, of which 306 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Obesity?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.