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NCT06309576 · ClinicalTrials.gov registry record · NA
Experimental Approach to Test Predictions of Body Weight Regulation Models
A NA study of Obesity and Underweight, sponsored by Pennington Biomedical Research Center.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06309576: Recruiting NA study of Obesity and Underweight, sponsored by Pennington Biomedical Research Center.
NCT06309576 is a NA study of Obesity and Underweight that is actively recruiting participants, run by Pennington Biomedical Research Center. The registered enrollment target is 12 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06309576, a NA study of Obesity and Underweight, is actively recruiting participants, sponsored by Pennington Biomedical Research Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions. In this pilot and feasibility study, the investigators will implement an experimental approach to test the predictions of models of body weight regulation in humans. Men and women with either low body weight or obesity will be exposed to a 2-day fasting followed by a 2-day ad-libitum refeeding. During the entire fasting-refeeding period, energy intake and expenditure will be accurately measured within metabolic chambers. The investigators will therefore determine the compensatory responses to fasting elicited to prevent weight loss. The results will serve to design and power future studies to better understand body weight regulation.
Primary Outcome
Cumulative energy balance during the fasting-refeeding cycle
Conditions Studied
Interventions
- BEHAVIORAL Fasting-refeeding cycle
Study Locations (1)
Louisiana
- Pennington Biomedical Research Center - Baton Rouge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2025-01-17 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT06309576 shows while recruiting
NCT06309576 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Obesity appearing as the primary indexed condition, and to 1 intervention - of which Fasting-refeeding cycle is the first listed.
NCT06309576 reports a single indexed study location in Louisiana.
Frequently Asked Questions
What is clinical trial NCT06309576 about?
NCT06309576 is a clinical study titled "Experimental Approach to Test Predictions of Body Weight Regulation Models". The regulation of human body weight and fatness is not fully understood. Although some models of regulation have been proposed (set point, dual-intervention point, others), no studies have been designed to test their predictions. In this pilot and feasibility study, the investigators will implement ...
What is the current status of trial NCT06309576?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2025-01-17. Estimated completion is 2026-06-30.
What conditions does trial NCT06309576 study?
This clinical trial studies the following conditions: Obesity, Underweight.
What interventions are being tested in trial NCT06309576?
The interventions under investigation include: Fasting-refeeding cycle (BEHAVIORAL).
Who is sponsoring clinical trial NCT06309576?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06309576 being conducted?
This trial has 1 study location across Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06309576's enrollment target sits among peer trials
12 1015th of 1053 higher than 30 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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