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NCT05745441 · ClinicalTrials.gov registry record · NA
Dinner Time for Obesity and Prediabetes
A NA study of Healthy and Obesity, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 2
- Study locations
NCT05745441: Recruiting NA study of Healthy and Obesity, sponsored by Johns Hopkins University.
NCT05745441 is a NA study of Healthy and Obesity that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 32 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05745441, a NA study of Healthy and Obesity, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 2
- Study locations
Study Summary
Obesity and its metabolic complications are leading causes of global morbidity and mortality. Evidence is mounting that inappropriate timing of food intake contributes to obesity. Specifically, late eating is associated with greater weight gain and metabolic syndrome. However, the mechanism by which late eating harms metabolism is not fully understood but may be related to mis-timing of food intake in relation to the body's endogenous circadian rhythm. Conversely, harmonization of eating timing with endogenous circadian rhythm may optimize metabolic health. In this study the investigators will use gold-standard methods of characterizing circadian rhythm in humans to examine the metabolic impacts food timing relative to endogenous circadian rhythm.
Primary Outcome
Within-subject difference in total fat oxidation between early dinner and late dinner conditions.
Conditions Studied
Interventions
- BEHAVIORAL Early Dinner
- BEHAVIORAL Late Dinner
- DRUG Early Dinner tracer
- DRUG Late Dinner tracer
Study Locations (2)
Maryland
- Johns Hopkins Bayview Medical Center - Baltimore
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2023-07-05 |
| Est. Completion | 2028-03-31 |
| Phase | NA |
What NCT05745441 shows while recruiting
NCT05745441 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (95% lower).
The record links to 3 conditions, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which Early Dinner is the first listed.
NCT05745441 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05745441 about?
NCT05745441 is a clinical study titled "Dinner Time for Obesity and Prediabetes". Obesity and its metabolic complications are leading causes of global morbidity and mortality. Evidence is mounting that inappropriate timing of food intake contributes to obesity. Specifically, late eating is associated with greater weight gain and metabolic syndrome. However, the mechanism by which...
What is the current status of trial NCT05745441?
This trial is currently recruiting. It is a NA study. The enrollment target is 32 participants. The study started on 2023-07-05. Estimated completion is 2028-03-31.
What conditions does trial NCT05745441 study?
This clinical trial studies the following conditions: Healthy, Obesity, PreDiabetes.
What interventions are being tested in trial NCT05745441?
The interventions under investigation include: Early Dinner (BEHAVIORAL), Late Dinner (BEHAVIORAL), Early Dinner tracer (DRUG), Late Dinner tracer (DRUG).
Who is sponsoring clinical trial NCT05745441?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05745441 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05745441's enrollment target sits among peer trials
32 647th of 1090 higher than 418 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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