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NCT07406295 · ClinicalTrials.gov registry record · NA
Respiratory Muscle Training to Improve Cerebrovascular and Immune Function
A NA study of Obesity and Immune Cells Activity, sponsored by Florida State University.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07406295: Recruiting NA study of Obesity and Immune Cells Activity, sponsored by Florida State University.
NCT07406295 is a NA study of Obesity and Immune Cells Activity that is actively recruiting participants, run by Florida State University. The registered enrollment target is 30 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07406295, a NA study of Obesity and Immune Cells Activity, is actively recruiting participants, sponsored by Florida State University.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals feel they do not have time to exercise. There is a need for a quicker type of training that improves brain health. Newly developed breathing exercises could be a time-efficient, cost-effective, and home-based practice to increase brain health. This practice acts as weightlifting for breathing muscles. These new breathing exercises have already been shown to increase heart health. Heart health is linked to brain health; if an intervention helps the heart, it is likely to also help the brain. It is currently unknown if breathing training can improve brain health in younger adults with obesity. The investigators will utilize the same 8-week program shown to improve heart health. Testing will be conducted before and after the breathing training. The first part of the study will determine if breathing exercises help brain health. Obesity also causes inflammation. This is measured via blood but affects the entire body. It is thought to cause some of the negative outcomes of obesity. By lowering inflammation, it is likely to improve overall health. Breathing exercises may reduce inflammation, but more research is required. The second part of this study will determine whether breathing exercises help reduce inflammation. This study will determine if brain health can be improved in adults with obesity. This could help 40% of American adults with obesity to live longer and healthier lives.
Primary Outcome
Middle cerebral artery blood velocity will be measured via transcranial Doppler ultrasound
Conditions Studied
Interventions
- DEVICE High intensity inspiratory muscle strength training
- DEVICE Low intensity
Study Locations (1)
Florida
- Florida State University - Tallahassee
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2026-01-27 |
| Est. Completion | 2028-05-01 |
| Phase | NA |
What NCT07406295 shows while recruiting
NCT07406295 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower).
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which High intensity inspiratory muscle strength training is the first listed.
NCT07406295 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT07406295 about?
NCT07406295 is a clinical study titled "Respiratory Muscle Training to Improve Cerebrovascular and Immune Function". Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals fe...
What is the current status of trial NCT07406295?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2026-01-27. Estimated completion is 2028-05-01.
What conditions does trial NCT07406295 study?
This clinical trial studies the following conditions: Obesity, Immune Cells Activity, Cerebrovascular Function.
What interventions are being tested in trial NCT07406295?
The interventions under investigation include: High intensity inspiratory muscle strength training (DEVICE), Low intensity (DEVICE).
Who is sponsoring clinical trial NCT07406295?
This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07406295 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07406295's enrollment target sits among peer trials
30 851st of 1053 higher than 173 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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