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NCT07406295 · ClinicalTrials.gov registry record · NA

Respiratory Muscle Training to Improve Cerebrovascular and Immune Function

A NA study of Obesity and Immune Cells Activity, sponsored by Florida State University.

Recruiting
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT07406295 is a NA study of Obesity and Immune Cells Activity that is actively recruiting participants, run by Florida State University. The registered enrollment target is 30 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07406295, a NA study of Obesity and Immune Cells Activity, is actively recruiting participants, sponsored by Florida State University.

RECRUITING
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals feel they do not have time to exercise. There is a need for a quicker type of training that improves brain health. Newly developed breathing exercises could be a time-efficient, cost-effective, and home-based practice to increase brain health. This practice acts as weightlifting for breathing muscles. These new breathing exercises have already been shown to increase heart health. Heart health is linked to brain health; if an intervention helps the heart, it is likely to also help the brain. It is currently unknown if breathing training can improve brain health in younger adults with obesity. The investigators will utilize the same 8-week program shown to improve heart health. Testing will be conducted before and after the breathing training. The first part of the study will determine if breathing exercises help brain health. Obesity also causes inflammation. This is measured via blood but affects the entire body. It is thought to cause some of the negative outcomes of obesity. By lowering inflammation, it is likely to improve overall health. Breathing exercises may reduce inflammation, but more research is required. The second part of this study will determine whether breathing exercises help reduce inflammation. This study will determine if brain health can be improved in adults with obesity. This could help 40% of American adults with obesity to live longer and healthier lives.

Interventions

  • DEVICE High intensity inspiratory muscle strength training
  • DEVICE Low intensity

Study Locations (1)

Florida

  • Florida State University - Tallahassee

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2026-01-27
Est. Completion 2028-05-01
Phase NA

Sponsor

Florida State University

219 total trials

What the Registry Record Tells You About NCT07406295

The ClinicalTrials.gov registry entry for NCT07406295 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (96% lower). The listed sponsor is Florida State University, which has 219 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which High intensity inspiratory muscle strength training is the first listed.

NCT07406295 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT07406295 about?

NCT07406295 is a clinical study titled "Respiratory Muscle Training to Improve Cerebrovascular and Immune Function". Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals fe...

What is the current status of trial NCT07406295?

This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2026-01-27. Estimated completion is 2028-05-01.

What conditions does trial NCT07406295 study?

This clinical trial studies the following conditions: Obesity, Immune Cells Activity, Cerebrovascular Function.

What interventions are being tested in trial NCT07406295?

The interventions under investigation include: High intensity inspiratory muscle strength training (DEVICE), Low intensity (DEVICE).

Who is sponsoring clinical trial NCT07406295?

This trial is sponsored by Florida State University, which has 219 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07406295 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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