University of North Carolina, Chapel Hill

725 total trials 499 currently recruiting 202 completed

Trial Pipeline

RECRUITING NA

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

NCT07337902

RECRUITING NA

CommunityRx-Kidney Health

NCT07237295

RECRUITING NA

Sugary Drink Labeling Study

NCT07294053

RECRUITING NA

Neural Mechanisms of Light Driven Analgesia

NCT07245303

RECRUITING NA

Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure

NCT07216820

RECRUITING NA

Sensory Spinal Cord Stimulation

NCT07095036

RECRUITING NA

REAL-Fam Feasibility Study for Youth Diabetes Management

NCT07212790

RECRUITING NA

Modulation of Brain Rhythms in Stroke

NCT07121582

RECRUITING NA

mHealth for Early Psychosis Caregivers in Statewide Program Outreach

NCT07225179

RECRUITING

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

NCT07237516

RECRUITING NA

Mindful Miles Pilot Feasibility Study

NCT07462429

RECRUITING

Immersive Physical Therapy in the Neonatal Intensive Care Unit (NICU)

NCT06927037

RECRUITING Phase 4

Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse

NCT07213635

RECRUITING NA

Co-Designing a Virtual Reality Intervention to Enhance Skill Development

NCT07186543

RECRUITING Phase 1

The DART DELIVER-02 Study

NCT07217379

RECRUITING NA

Healthy Living Anson Study

NCT07126587

RECRUITING NA

Affect-based Impulsivity in Borderline Personality Disorder

NCT06880640

RECRUITING NA

Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine

NCT07148713

RECRUITING NA

Caring for the Carer

NCT07167641

RECRUITING NA

Caring Connections Youth Suicide Detection and Intervention Study

NCT06353711

RECRUITING NA

Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)

NCT06979154

RECRUITING Phase 4

Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch

NCT06864403

RECRUITING NA

Comparing a Workplace Resilience and a Physical Activity Intervention on Early Childhood Educators Well-being

NCT06919952

RECRUITING

Microplastic Exposure From Clear Aligner Wear (MPE)

NCT06934603

RECRUITING NA

Anterior Cruciate Ligaments: Studying Updates in neuroCognition After Knee Manipulation

NCT07058467

RECRUITING NA

Resources for Optimizing Outcomes in Toddlers on the Spectrum

NCT07086781

RECRUITING NA

Preventing Type 2 Diabetes in Black Emergent Adult

NCT06848244

RECRUITING NA

A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™

NCT06649890

RECRUITING

Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery

NCT06988176

RECRUITING

19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

NCT06066723

RECRUITING NA

Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.

NCT06991296

RECRUITING

Mirikizumab Real World Protocol

NCT06696014

RECRUITING NA

Improving Parental Support in Hypospadias Care

NCT06832280

RECRUITING NA

Alcohol Labeling Study

NCT06835920

RECRUITING NA

Neuroscience of Psychotherapy for Depression

NCT06696001

RECRUITING NA

Connect-Home: Alzheimer's Disease and Related Dementias

NCT06840587

RECRUITING Phase 2

Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

NCT06636786

RECRUITING NA

Stress Trajectories and Anhedonia in Adolescence Research Study

NCT07040449

RECRUITING NA

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

NCT06724406

RECRUITING NA

Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes

NCT05741125

RECRUITING NA

Treating Binge Eating and Obesity Digitally in Black Women

NCT05693896

RECRUITING NA

Physical Activity and Community EmPOWERment Project

NCT06740162

RECRUITING NA

Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations

NCT06735976

RECRUITING NA

Resilience Through Interventions for Successful Early Outcomes

NCT06669624

RECRUITING NA

Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction

NCT05949177

RECRUITING

Eating Disorders Genetics Initiative 2

NCT06594913

RECRUITING Phase 4

Hypertonic Saline in NCFB

NCT06242795

RECRUITING NA

Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)

NCT06587230

RECRUITING NA

Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART

NCT06405373

RECRUITING Phase 4

Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression

NCT06610305

RECRUITING NA

Promoting Improved Functioning Among People Experiencing Stressful Situations

NCT06482567

RECRUITING Phase 1

Dose Optimization of Caffeine for HIE

NCT06448780

RECRUITING NA

Flexibility, Alcohol Misuse, and Excitation

NCT06634771

RECRUITING Phase 4

Rifaximin for the Secondary Prevention of Recurrent Pouchitis

NCT06312683

RECRUITING NA

Effects of "Alliance180 Program" on Well-Being

NCT06451523

RECRUITING NA

A Pragmatic Rehabilitation Intervention: The Active Rehab Study

NCT05320822

RECRUITING Phase 4

Beta-Blocker Influences on Inflammatory and Neural Responses to Stress

NCT06263452

RECRUITING NA

Apathy in Parkinson Disease TMS Study

NCT06087926

RECRUITING NA

Ultrasound for Evaluation of Percutaneous G-tube Position

NCT06361498

RECRUITING Phase 2

The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study

NCT06059664

RECRUITING Phase 3

Psilocybin-Assisted Therapy in Treatment-Resistant Depression

NCT06303739

RECRUITING NA

Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults

NCT06044571

RECRUITING NA

Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce

NCT06239688

RECRUITING Phase 3

Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery

NCT06179004

RECRUITING NA

3-D Tractography FUS Ablation for Essential Tremor

NCT06331052

RECRUITING NA

Adverse Adolescent Pathways to Substance Use

NCT06977178

RECRUITING NA

Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development

NCT06208085

RECRUITING NA

Feasibility Test of Action Planning in Pediatric IBD

NCT06186752

RECRUITING NA

Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults

NCT06060860

RECRUITING NA

The Validation Study of Bioelectronics

NCT05397951

RECRUITING NA

Fit for Duty: mHealth Intervention for Weight Gain Prevention

NCT06110273

RECRUITING NA

Precision Medicine and Physical Function

NCT05877846

RECRUITING NA

GI Alpha-Gal Study

NCT06268717

RECRUITING NA

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

NCT06096324

RECRUITING NA

Virtual Reality Mindfulness Meditation After ACL Reconstruction

NCT05527171

RECRUITING NA

Adolescent Mood During Puberty and Testosterone

NCT06072677

RECRUITING NA

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

NCT05864157

RECRUITING NA

Cochlear Implants in Young Children With SSD

NCT05775367

RECRUITING NA

Gait Rehabilitation to Treat FastOA

NCT05848622

RECRUITING NA

Accountability for Care Through Undoing Racism & Equity for Moms

NCT05484804

RECRUITING NA

Animal Assisted Therapy in Pediatric Dentistry

NCT05464888

RECRUITING Phase 2

Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI

NCT05480995

RECRUITING NA

Depression, Aging, Stress and Heart Health Study

NCT05570721

RECRUITING NA

Sitting Interruption and Whole-body Cardiovascular Health

NCT05316571

RECRUITING NA

Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)

NCT05233150

RECRUITING Phase 4

Examining the Effects of Estradiol on Neural and Molecular Response to Reward

NCT05282277

RECRUITING NA

Food as Medicine for HIV and Diabetes

NCT05026723

RECRUITING

Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis

NCT06057714

RECRUITING NA

Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury

NCT04875052

RECRUITING Phase 1

Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism

NCT04328337

RECRUITING

Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses

NCT04117360

RECRUITING NA

Synergistic Activity of Human Milk Nutrients and Infant Cognition

NCT03838536

RECRUITING

Pharmacokinetics of Off Label Pediatric Medications

NCT01286519

RECRUITING

Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease

NCT00807482

ACTIVE NOT RECRUITING NA

Omega-3 Supplementation for Pediatric Migraine

NCT06899074

ACTIVE NOT RECRUITING NA

Collaborate and Leverage Evidence in African American Rural Network

NCT06730633

ACTIVE NOT RECRUITING

Long-term Outcomes of Complex Conversion Total Hip Arthroplasty

NCT06533020

ACTIVE NOT RECRUITING NA

Perineal Massage for Pessary Examinations

NCT06416982

ACTIVE NOT RECRUITING Phase 2

Anifrolumab for Hidradenitis Suppurativa

NCT06374212

ACTIVE NOT RECRUITING NA

Forging New Paths: Building Interventions to Treat Criminogenic Needs in Community Based Mental Health Settings

NCT06290648

Phase Distribution

PhaseTrial count
Phase 1 49
Phase 2 55
Phase 3 5
Phase 4 14

What the Pipeline for University of North Carolina, Chapel Hill Shows

According to the ClinicalTrials.gov registry, University of North Carolina, Chapel Hill is linked to 725 US clinical trials across every stage of research activity. Of those, 499 studies are currently recruiting — about 69% of the sponsor's indexed portfolio — and 202 are already marked complete, representing roughly 28% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of North Carolina, Chapel Hill reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 104 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of North Carolina, Chapel Hill is Obesity with 17 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial