University of North Carolina, Chapel Hill
Trial Pipeline
Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)
NCT07337902
CommunityRx-Kidney Health
NCT07237295
Sugary Drink Labeling Study
NCT07294053
Neural Mechanisms of Light Driven Analgesia
NCT07245303
Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure
NCT07216820
Sensory Spinal Cord Stimulation
NCT07095036
REAL-Fam Feasibility Study for Youth Diabetes Management
NCT07212790
Modulation of Brain Rhythms in Stroke
NCT07121582
mHealth for Early Psychosis Caregivers in Statewide Program Outreach
NCT07225179
Zymfentra (Infliximab-dyyb) REal World Cohort STudy
NCT07237516
Mindful Miles Pilot Feasibility Study
NCT07462429
Immersive Physical Therapy in the Neonatal Intensive Care Unit (NICU)
NCT06927037
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
NCT07213635
Co-Designing a Virtual Reality Intervention to Enhance Skill Development
NCT07186543
The DART DELIVER-02 Study
NCT07217379
Healthy Living Anson Study
NCT07126587
Affect-based Impulsivity in Borderline Personality Disorder
NCT06880640
Pilot of Continuous Glucose Monitor-Augmented Food Is Medicine
NCT07148713
Caring for the Carer
NCT07167641
Caring Connections Youth Suicide Detection and Intervention Study
NCT06353711
Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)
NCT06979154
Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch
NCT06864403
Comparing a Workplace Resilience and a Physical Activity Intervention on Early Childhood Educators Well-being
NCT06919952
Microplastic Exposure From Clear Aligner Wear (MPE)
NCT06934603
Anterior Cruciate Ligaments: Studying Updates in neuroCognition After Knee Manipulation
NCT07058467
Resources for Optimizing Outcomes in Toddlers on the Spectrum
NCT07086781
Preventing Type 2 Diabetes in Black Emergent Adult
NCT06848244
A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™
NCT06649890
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
NCT06988176
19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
NCT06066723
Concentration of n-3 PUFA Monohydroxylated Derivatives in Adults With Obesity After n-3 PUFA Supplementation.
NCT06991296
Mirikizumab Real World Protocol
NCT06696014
Improving Parental Support in Hypospadias Care
NCT06832280
Alcohol Labeling Study
NCT06835920
Neuroscience of Psychotherapy for Depression
NCT06696001
Connect-Home: Alzheimer's Disease and Related Dementias
NCT06840587
Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)
NCT06636786
Stress Trajectories and Anhedonia in Adolescence Research Study
NCT07040449
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
NCT06724406
Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes
NCT05741125
Treating Binge Eating and Obesity Digitally in Black Women
NCT05693896
Physical Activity and Community EmPOWERment Project
NCT06740162
Efficacy & Safety of LOBO™ Vascular Occlusion Device for Embolization of Pulmonary Arteriovenous Malformations
NCT06735976
Resilience Through Interventions for Successful Early Outcomes
NCT06669624
Graded Exposure and Mindfulness Meditation for Patients Post-ACL Reconstruction
NCT05949177
Eating Disorders Genetics Initiative 2
NCT06594913
Hypertonic Saline in NCFB
NCT06242795
Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
NCT06587230
Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART
NCT06405373
Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression
NCT06610305
Promoting Improved Functioning Among People Experiencing Stressful Situations
NCT06482567
Dose Optimization of Caffeine for HIE
NCT06448780
Flexibility, Alcohol Misuse, and Excitation
NCT06634771
Rifaximin for the Secondary Prevention of Recurrent Pouchitis
NCT06312683
Effects of "Alliance180 Program" on Well-Being
NCT06451523
A Pragmatic Rehabilitation Intervention: The Active Rehab Study
NCT05320822
Beta-Blocker Influences on Inflammatory and Neural Responses to Stress
NCT06263452
Apathy in Parkinson Disease TMS Study
NCT06087926
Ultrasound for Evaluation of Percutaneous G-tube Position
NCT06361498
The EFfect of FinErenone in Kidney TransplantiOn Recipients: The EFFEKTOR Study
NCT06059664
Psilocybin-Assisted Therapy in Treatment-Resistant Depression
NCT06303739
Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults
NCT06044571
Evaluating a National Person-Centered Training Program to Strengthen the Dementia Care Workforce
NCT06239688
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
NCT06179004
3-D Tractography FUS Ablation for Essential Tremor
NCT06331052
Adverse Adolescent Pathways to Substance Use
NCT06977178
Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development
NCT06208085
Feasibility Test of Action Planning in Pediatric IBD
NCT06186752
Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults
NCT06060860
The Validation Study of Bioelectronics
NCT05397951
Fit for Duty: mHealth Intervention for Weight Gain Prevention
NCT06110273
Precision Medicine and Physical Function
NCT05877846
GI Alpha-Gal Study
NCT06268717
Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)
NCT06096324
Virtual Reality Mindfulness Meditation After ACL Reconstruction
NCT05527171
Adolescent Mood During Puberty and Testosterone
NCT06072677
Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease
NCT05864157
Cochlear Implants in Young Children With SSD
NCT05775367
Gait Rehabilitation to Treat FastOA
NCT05848622
Accountability for Care Through Undoing Racism & Equity for Moms
NCT05484804
Animal Assisted Therapy in Pediatric Dentistry
NCT05464888
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
NCT05480995
Depression, Aging, Stress and Heart Health Study
NCT05570721
Sitting Interruption and Whole-body Cardiovascular Health
NCT05316571
Child-Adult Relationship Enhancement in Primary Care (PriCARE) / Criando Niños Con CARIÑO (CARIÑO)
NCT05233150
Examining the Effects of Estradiol on Neural and Molecular Response to Reward
NCT05282277
Food as Medicine for HIV and Diabetes
NCT05026723
Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis
NCT06057714
Vibration and Post-traumatic Osteoarthritis Risk Following ACL Injury
NCT04875052
Investigating Whether Acute Elevation of Fatty Acid Levels Alters Cerebral Glucose Transport and Metabolism
NCT04328337
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
NCT04117360
Synergistic Activity of Human Milk Nutrients and Infant Cognition
NCT03838536
Pharmacokinetics of Off Label Pediatric Medications
NCT01286519
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease
NCT00807482
Omega-3 Supplementation for Pediatric Migraine
NCT06899074
Collaborate and Leverage Evidence in African American Rural Network
NCT06730633
Long-term Outcomes of Complex Conversion Total Hip Arthroplasty
NCT06533020
Perineal Massage for Pessary Examinations
NCT06416982
Anifrolumab for Hidradenitis Suppurativa
NCT06374212
Forging New Paths: Building Interventions to Treat Criminogenic Needs in Community Based Mental Health Settings
NCT06290648
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 49 |
| Phase 2 | 55 |
| Phase 3 | 5 |
| Phase 4 | 14 |
Therapeutic Areas
What the Pipeline for University of North Carolina, Chapel Hill Shows
According to the ClinicalTrials.gov registry, University of North Carolina, Chapel Hill is linked to 725 US clinical trials across every stage of research activity. Of those, 499 studies are currently recruiting — about 69% of the sponsor's indexed portfolio — and 202 are already marked complete, representing roughly 28% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of North Carolina, Chapel Hill reports 19 late-stage studies (Phase 3 and Phase 4 combined) and 104 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of North Carolina, Chapel Hill is Obesity with 17 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.