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NCT06416969 · ClinicalTrials.gov registry record · Early Phase 1
Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation
A Early Phase 1 study of Obesity, sponsored by Mayo Clinic.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT06416969: Recruiting Early Phase 1 study of Obesity, sponsored by Mayo Clinic.
NCT06416969 is a Early Phase 1 study of Obesity that is actively recruiting participants, run by Mayo Clinic. The registered enrollment target is 24 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06416969, a Early Phase 1 study of Obesity, is actively recruiting participants, sponsored by Mayo Clinic.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Adults who gain most of their excess weight in the abdominal area typically do not respond to factors that "turn on" fat cells the same way as people who don't have excessive weight. Researchers are trying to understand why fat tissue responds differently in people with different body types.
Primary Outcome
regional palmitate release rates (micromol/min) will be measured using a combination of leg and splanchnic blood flow combined with stable isotope tracer measurements of palmitate uptake and release across the leg and splanchnic bed. Upper body, non-splanchnic palmitate release will be calculated as: total palmitate release - (splanchnic palmitate release + (leg palmitate release x 2)). Release rates will be measured at baseline (overnight fasting) and in response to the infusion of somatostatin
Conditions Studied
Interventions
- DRUG Somatostatin
- DRUG Epinephrine
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-01-01 |
| Est. Completion | 2027-04-01 |
| Phase | Early Phase 1 |
What NCT06416969 shows while recruiting
NCT06416969 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 2 interventions - of which Somatostatin is the first listed.
NCT06416969 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT06416969 about?
NCT06416969 is a clinical study titled "Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation". Adults who gain most of their excess weight in the abdominal area typically do not respond to factors that "turn on" fat cells the same way as people who don't have excessive weight. Researchers are trying to understand why fat tissue responds differently in people with different body types.
What is the current status of trial NCT06416969?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 24 participants. The study started on 2024-01-01. Estimated completion is 2027-04-01.
What conditions does trial NCT06416969 study?
This clinical trial studies the following conditions: Obesity.
What interventions are being tested in trial NCT06416969?
The interventions under investigation include: Somatostatin (DRUG), Epinephrine (DRUG).
Who is sponsoring clinical trial NCT06416969?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06416969 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Obesity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06416969's enrollment target sits among peer trials
24 909th of 1053 higher than 127 of 1,053 other Obesity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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