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ClinicalTrials.gov 72 recruiting now official registry

Gastric Cancer clinical trials

72 of 159 indexed Gastric Cancer trials are currently recruiting.

159 US clinical trials · 72 currently recruiting

Gastric Cancer is the subject of 159 registered US clinical trials on ClinicalTrials.gov, 72 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 118 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 11 of these trials.

The research picture

Gastric Cancer has 159 registered US clinical trials, 72 of them open to new participants right now, about 45% of the total.

72
recruiting participants now
45%
of trials open to enrollment
17
in Phase 3–4 (later-stage)
11
top sponsor: AstraZeneca
Phase 169Phase 249Phase 313Phase 44

Active & Recent Trials

159 total, page 1 of 4

RECRUITING 5,000 participants

Gastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer Patients

Vanderbilt University Medical Center

NCT00899626

RECRUITING 3,200 participants

A Study Collecting Health Information to Understand and Prevent Gastric Cancer

Memorial Sloan Kettering Cancer Center

NCT06370143

RECRUITING 2,500 participants

EsophaCap for the Detection of Early Esophageal Carcinoma

Johns Hopkins University

NCT04214119

RECRUITING Phase 3 2,130 participants

Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

AstraZeneca

NCT07431281

RECRUITING Phase 2 740 participants

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

Daiichi Sankyo

NCT06172478

RECRUITING Phase 3 726 participants

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

Daiichi Sankyo

NCT06731478

RECRUITING Phase 1 714 participants

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

Seagen, a wholly owned subsidiary of Pfizer

NCT05208762

RECRUITING NA 625 participants

Comprehensive Outcomes for After Cancer Health

Pack Health

NCT05349227

RECRUITING 620 participants

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

University of Missouri-Columbia

NCT02838836

RECRUITING 600 participants

The GAstric Precancerous Conditions Study

Stanford University

NCT04191551

RECRUITING Phase 3 572 participants

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

AstraZeneca

NCT06346392

RECRUITING Phase 3 550 participants

A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

Shanghai Henlius Biotech

NCT06532006

RECRUITING Phase 1 523 participants

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

Merus B.V.

NCT03526835

RECRUITING 500 participants

The Gastric Cancer Foundation: A Gastric Cancer Registry

Stanford University

NCT01514045

RECRUITING 500 participants

Detection of Minimal Residual Disease Using Exosomal miRNA Distant Metastasis Markers

City of Hope Medical Center

NCT07243015

RECRUITING Phase 2 497 participants

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

Apollomics

NCT03175224

RECRUITING Phase 2 454 participants

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

AstraZeneca

NCT05489211

RECRUITING Phase 2 450 participants

Ph1b/2 Study of the Safety and Efficacy of T-DXd Combinations in Advanced HER2-expressing Gastric Cancer (DESTINY-Gastric03)

AstraZeneca

NCT04379596

RECRUITING Phase 1 450 participants

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7502175 as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT05581004

RECRUITING Phase 1 405 participants

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

ArriVent BioPharma

NCT07066657

RECRUITING 400 participants

Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis

National Cancer Institute (NCI)

NCT04557969

RECRUITING Phase 1 345 participants

A Study of NX-1607 in Adults With Advanced Malignancies

Nurix Therapeutics

NCT05107674

RECRUITING Phase 1 330 participants

Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors

I-Mab Biopharma US Limited

NCT04900818

RECRUITING 320 participants

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

University of Missouri-Columbia

NCT03551951

RECRUITING Phase 2 320 participants

18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer Detection

National Cancer Institute (NCI)

NCT06503146

RECRUITING NA 300 participants

Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)

University of California, Davis

NCT06101277

RECRUITING Phase 1 280 participants

Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors

AstraZeneca

NCT06005493

RECRUITING Phase 1 280 participants

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

SystImmune

NCT06293898

RECRUITING Phase 1 260 participants

BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia

SillaJen

NCT05768932

RECRUITING Phase 1 258 participants

A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors

BeiGene

NCT06257264

RECRUITING NA 257 participants

Resilience and Equity in Aging, Cancer, and Health (REACH)

Dana-Farber Cancer Institute

NCT04674267

RECRUITING Phase 1 250 participants

Study of Anti-CEACAM5 ADC M9140 in Participants With Advanced Solid Tumors (PROCEADE PanTumor)

EMD Serono Research & Development Institute

NCT06710132

RECRUITING Phase 2 240 participants

Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers

Udai Kammula

NCT03935893

RECRUITING Phase 2 224 participants

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

AstraZeneca

NCT06219941

RECRUITING Phase 1 200 participants

A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer

Sutro Biopharma

NCT07227168

RECRUITING Phase 2 200 participants

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

Jazz Pharmaceuticals

NCT06695845

RECRUITING Phase 2 180 participants

Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

I-Mab Biopharma US Limited

NCT07432295

RECRUITING Phase 1 165 participants

IKS014 in Advanced Solid Tumors That Express HER2

Iksuda Therapeutics

NCT05872295

RECRUITING Phase 2 163 participants

Novel Combinations in Participants With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

AstraZeneca

NCT05702229

RECRUITING 150 participants

Molecular and Epidemiological Risk Factors in the Development of Gastric Cancer

The University of Texas Health Science Center at San Antonio

NCT04600466

RECRUITING Phase 2 146 participants

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

Toray Industries

NCT06038578

RECRUITING Phase 1 135 participants

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

Chimeric Therapeutics

NCT06055439

RECRUITING Phase 1 134 participants

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

Neonc Technologies

NCT06047379

RECRUITING Phase 1 132 participants

Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors

MOMA Therapeutics

NCT06974110

RECRUITING Phase 1 117 participants

Study for AZD4360 in Participants With Advanced Solid Tumours

AstraZeneca

NCT06921928

RECRUITING Phase 1 117 participants

Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies

Anwaar Saeed

NCT03539822

RECRUITING Phase 1 115 participants

A Beta-only IL-2 ImmunoTherapY Study

Medicenna Therapeutics

NCT05086692

RECRUITING Phase 1 115 participants

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

ModeX Therapeutics, An OPKO Health Company

NCT06239194

RECRUITING Phase 1 112 participants

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Perspective Therapeutics

NCT06710756

RECRUITING Phase 1 110 participants

Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients

National Cancer Institute (NCI)

NCT03190941

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Phase Distribution

PhaseTrial count
Phase 1 69
Phase 2 49
Phase 3 13
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Gastric Cancer Trial Landscape

159 indexed Gastric Cancer studies · 72 recruiting (45%).

Phase mix: 17 late (III/IV) vs 118 early (I/II).

Top sponsor: AstraZeneca (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Gastric Cancer?

PlainTrial tracks 159 US clinical trials for Gastric Cancer, of which 72 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Gastric Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.