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NCT04214119 · ClinicalTrials.gov registry record
EsophaCap for the Detection of Early Esophageal Carcinoma
A clinical trial of Gastric Cancer and Esophageal Cancer, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- 2,500
- Enrollment target
- 2
- Study locations
NCT04214119: Recruiting study of Gastric Cancer and Esophageal Cancer, sponsored by Johns Hopkins University.
NCT04214119 is a study of Gastric Cancer and Esophageal Cancer that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 2,500 participants, above the 303-participant average among 153 other Gastric Cancer trials with a reported enrollment target (725% higher). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04214119, a study of Gastric Cancer and Esophageal Cancer, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- 2,500 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.
Primary Outcome
Using DNA methylation, we plan on identifying, from a pool of highly selected marker candidates, the best biomarkers that are aberrantly methylated in Barrett's esophagus versus control in order to differentiate between subjects who have Barrett's esophagus and those who do not have Barrett's esophagus. This is measure using methylation index and the calculated probability score from different methylation index values.
Conditions Studied
Study Locations (2)
Maryland
- Bayview Medical Center - Baltimore
- Johns Hopkins Hospital - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,500 participants |
| Start Date | 2016-01-12 |
| Est. Completion | 2028-12-19 |
What NCT04214119 shows while recruiting
NCT04214119 is an observational study that tracks outcomes without assigning an intervention. Its 2,500 participants enrollment target places it among the larger protocols in the corpus, above the 303-participant average among 153 other Gastric Cancer trials with a reported enrollment target (725% higher).
The record links to 3 conditions, with Gastric Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT04214119 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04214119 about?
NCT04214119 is a clinical study titled "EsophaCap for the Detection of Early Esophageal Carcinoma". This study is to identify potential biomarkers for the early detection of Barrett's Esophagus, esophageal carcinoma (both adenocarcinoma and squamous cell carcinoma), and gastric cancer via sponge cytology.
What is the current status of trial NCT04214119?
This trial is currently recruiting. The enrollment target is 2,500 participants. The study started on 2016-01-12. Estimated completion is 2028-12-19.
What conditions does trial NCT04214119 study?
This clinical trial studies the following conditions: Gastric Cancer, Esophageal Cancer, Barrett Esophagus.
Who is sponsoring clinical trial NCT04214119?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04214119 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gastric Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04214119's enrollment target sits among peer trials
2,500 4th of 153 higher than 150 of 153 other Gastric Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gastric Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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