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RECRUITING Phase 2

A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer

NCT06038578 · View on ClinicalTrials.gov ↗

Study Summary

This study will assess the efficacy, safety, optimal dose and ADA and NAbs development of TRK-950 at two separate dose levels in combination with ramucirumab and paclitaxel (RAM+PTX) as compared with RAM + PTX treatment alone in participants with gastric or gastro-esophageal junction (GEJ) adenocarcinoma.

Interventions

  • DRUG Paclitaxel
  • DRUG Ramucirumab
  • BIOLOGICAL TRK-950

Study Locations (20)

Texas

  • Texas Oncology Arlington North — Arlington
  • Texas Oncology Bedford — Bedford
  • Texas Oncology Dallas Methodist — Dallas
  • Texas Oncology Dallas Medical City — Dallas
  • Texas Oncology Dallas Presbyterian — Dallas
  • Texas Oncology Methodist Charlton Cancer Center — Dallas
  • Texas Oncology-Sammons Cancer Center — Dallas
  • Texas Oncology Fort Worth Cancer Center — Fort Worth
  • Texas Oncology Grapevine — Grapevine
  • Texas Oncology Plano East — Plano
  • Texas Oncology Plano West — Plano

California

  • City of Hope — Duarte
  • City of Hope at Orange County Lennar Foundation Cancer Center — Irvine
  • University of California, Los Angeles — Santa Monica

Other

  • National Cancer Center Hospital — Chūōku
  • Osaka International Cancer Institute — Chūōku
  • National Cancer Center Hospital East — Kashiwa

Kanagawa

  • Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center — Yokohama

Saitama

  • Saitama Prefectural Hospital Organization Saitama Cancer Center — Shinden

Shizuoka

  • Shizuoka Cancer Center — Nagaizumi-cho

Trial Details

FieldValue
Enrollment Target 146 participants
Start Date 2023-10-04
Est. Completion 2026-06-30
Phase Phase 2

Sponsor

Toray Industries

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06038578

The ClinicalTrials.gov registry entry for NCT06038578 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 146 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Toray Industries, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 3 conditions, with Gastric Cancer appearing as the primary indexed condition, and to 3 interventions — of which Paclitaxel is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06038578 reports 20 study locations spanning 6 distinct geographic areas — top geographies include Texas, California, Other. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06038578 about?

NCT06038578 is a clinical study titled "A Study of TRK-950 When Used in Combination With Ramucirumab and Paclitaxel in Patients With Gastric Cancer". This study will assess the efficacy, safety, optimal dose and ADA and NAbs development of TRK-950 at two separate dose levels in combination with ramucirumab and paclitaxel (RAM+PTX) as compared with RAM + PTX treatment alone in participants with gastric or gastro-esophageal junction (GEJ) adenocarc...

What is the current status of trial NCT06038578?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 146 participants. The study started on 2023-10-04. Estimated completion is 2026-06-30.

What conditions does trial NCT06038578 study?

This clinical trial studies the following conditions: Gastric Cancer, Gastric Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06038578?

The interventions under investigation include: Paclitaxel (DRUG), Ramucirumab (DRUG), TRK-950 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06038578?

This trial is sponsored by Toray Industries, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06038578 being conducted?

This trial has 20 study locations across California, Texas, Kanagawa, Saitama, Shizuoka. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial