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A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
NCT07066657 · View on ClinicalTrials.gov ↗
Study Summary
This is an open-label, multi-center, phase I study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of MRG007 (ARR-217) in patients with unresectable locally advanced or metastatic solid tumors.
Conditions Studied
Interventions
- DRUG MRG007
Study Locations (15)
California
- ULCA — Los Angeles
- UCSF — San Francisco
Colorado
- University of Colorado — Aurora
- Sarah Cannon Research Institute — Denver
Texas
- MD Anderson Cancer Center — Houston
- NEXT Dallas — Irving
Shanghai Municipality
- Renji Hospital Shanghai Jiaotong University School of Medicine — Shanghai
- Zhongshan Hospital Fudan University — Shanghai
Florida
- Sarah Cannon Research Institute — Sarasota
Tennessee
- Sarah Cannon Research Institute — Nashville
Virginia
- NEXT Virginia — Fairfax
Washington
- Fred Hutchinson Cancer Center — Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 405 participants |
| Start Date | 2025-07-25 |
| Est. Completion | 2030-12 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07066657
The ClinicalTrials.gov registry entry for NCT07066657 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 405 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is ArriVent BioPharma, which has 35 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention — of which MRG007 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07066657 reports 15 study locations spanning 11 distinct geographic areas — top geographies include California, Colorado, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07066657 about?
NCT07066657 is a clinical study titled "A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors". This is an open-label, multi-center, phase I study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of MRG007 (ARR-217) in patients with unresectable locally advanced or metastatic solid tumors.
What is the current status of trial NCT07066657?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 405 participants. The study started on 2025-07-25. Estimated completion is 2030-12.
What conditions does trial NCT07066657 study?
This clinical trial studies the following conditions: Colorectal Cancer, Pancreatic Cancer, Gastric Cancer, Locally Advanced or Metastatic Solid Tumors. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07066657?
The interventions under investigation include: MRG007 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07066657?
This trial is sponsored by ArriVent BioPharma, which has 35 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07066657 being conducted?
This trial has 15 study locations across California, Colorado, Florida, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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