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NCT07066657 · ClinicalTrials.gov registry record · Phase 1

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

A Phase 1 study of Colorectal Cancer and Pancreatic Cancer, sponsored by ArriVent BioPharma.

Recruiting
Registry status
Phase 1
Development phase
405
Enrollment target
15
Study locations

NCT07066657 is a Phase 1 study of Colorectal Cancer and Pancreatic Cancer that is actively recruiting participants, run by ArriVent BioPharma. The registered enrollment target is 405 participants, below the 1,510-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (73% lower). The trial reports 15 study locations across 11 states.

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The verdict

NCT07066657, a Phase 1 study of Colorectal Cancer and Pancreatic Cancer, is actively recruiting participants, sponsored by ArriVent BioPharma.

RECRUITING
Registry status
Phase 1
Development phase
405 participants
Enrollment target
15
Study locations

Study Summary

This is an open-label, multi-center, phase I study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of MRG007 (ARR-217) in patients with unresectable locally advanced or metastatic solid tumors.

Interventions

  • DRUG MRG007

Study Locations (15)

California

  • ULCA - Los Angeles
  • UCSF - San Francisco

Colorado

  • University of Colorado - Aurora
  • Sarah Cannon Research Institute - Denver

Texas

  • MD Anderson Cancer Center - Houston
  • NEXT Dallas - Irving

Shanghai Municipality

  • Renji Hospital Shanghai Jiaotong University School of Medicine - Shanghai
  • Zhongshan Hospital Fudan University - Shanghai

Florida

  • Sarah Cannon Research Institute - Sarasota

Tennessee

  • Sarah Cannon Research Institute - Nashville

Virginia

  • NEXT Virginia - Fairfax

Washington

  • Fred Hutchinson Cancer Center - Seattle

Trial Details

FieldValue
Enrollment Target 405 participants
Start Date 2025-07-25
Est. Completion 2030-12
Phase Phase 1

Sponsor

ArriVent BioPharma

4 total trials

What the Registry Record Tells You About NCT07066657

The ClinicalTrials.gov registry entry for NCT07066657 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 405 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,510-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (73% lower). The listed sponsor is ArriVent BioPharma, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which MRG007 is the first listed.

NCT07066657 reports 15 study locations spanning 11 distinct geographic areas - top geographies include California, Colorado, Texas.

Frequently Asked Questions

What is clinical trial NCT07066657 about?

NCT07066657 is a clinical study titled "A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors". This is an open-label, multi-center, phase I study to evaluate the safety, tolerability, efficacy, and pharmacokinetics of MRG007 (ARR-217) in patients with unresectable locally advanced or metastatic solid tumors.

What is the current status of trial NCT07066657?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 405 participants. The study started on 2025-07-25. Estimated completion is 2030-12.

What conditions does trial NCT07066657 study?

This clinical trial studies the following conditions: Colorectal Cancer, Pancreatic Cancer, Gastric Cancer, Locally Advanced or Metastatic Solid Tumors.

What interventions are being tested in trial NCT07066657?

The interventions under investigation include: MRG007 (DRUG).

Who is sponsoring clinical trial NCT07066657?

This trial is sponsored by ArriVent BioPharma, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07066657 being conducted?

This trial has 15 study locations across California, Colorado, Florida, Tennessee, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.