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RECRUITING Phase 1

Study for AZD4360 in Participants With Advanced Solid Tumours

NCT06921928 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics, and preliminary efficacy of AZD4360 in adult participants with locally advanced or metastatic solid tumours selected for expression of CLDN18.2.

Interventions

  • DRUG AZD4360

Study Locations (17)

Other

  • Research Site — Beijing
  • Research Site — Chengdu
  • Research Site — Shanghai
  • Research Site — Wuhan
  • Research Site — Berlin
  • Research Site — Dresden
  • Research Site — Frankfurt
  • Research Site — Chūōku
  • Research Site — Kashiwa
  • Research Site — Kōtoku
  • Research Site — Glasgow
  • Research Site — Leeds
  • Research Site — London
  • Research Site — Oxford

California

  • Research Site — Santa Monica

Rhode Island

  • Research Site — Providence

Texas

  • Research Site — Houston

Trial Details

FieldValue
Enrollment Target 117 participants
Start Date 2025-04-29
Est. Completion 2027-12-16
Phase Phase 1

Sponsor

AstraZeneca

1,053 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06921928

The ClinicalTrials.gov registry entry for NCT06921928 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 117 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is AstraZeneca, which has 1,053 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 4 conditions, with Gastric Cancer appearing as the primary indexed condition, and to 1 intervention — of which AZD4360 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06921928 reports 17 study locations spanning 4 distinct geographic areas — top geographies include Other, California, Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06921928 about?

NCT06921928 is a clinical study titled "Study for AZD4360 in Participants With Advanced Solid Tumours". The purpose of this study is to evaluate the safety, tolerability, PK, immunogenicity, pharmacodynamics, and preliminary efficacy of AZD4360 in adult participants with locally advanced or metastatic solid tumours selected for expression of CLDN18.2.

What is the current status of trial NCT06921928?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 117 participants. The study started on 2025-04-29. Estimated completion is 2027-12-16.

What conditions does trial NCT06921928 study?

This clinical trial studies the following conditions: Gastric Cancer, Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancer, Gastroesophageal Junction Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06921928?

The interventions under investigation include: AZD4360 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06921928?

This trial is sponsored by AstraZeneca, which has 1,053 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06921928 being conducted?

This trial has 17 study locations across California, Rhode Island, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial