NGM Biopharmaceuticals
NGM Biopharmaceuticals sponsors 18 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 14 completed. 0 of these trials are in Phase 3-4 (later-stage) and 18 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Squamous Cell Carcinoma of Head and Neck, with 3 trials.
Trial Pipeline
18 total, page 1 of 1
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
NCT07033026
Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors
NCT05311618
Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors
NCT05215574
Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies
NCT04913337
Study of Aldafermin (NGM282) in Healthy Adult Male Japanese and Non-Japanese Subjects
NCT04828265
Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function
NCT04823702
A Study of NGM621 in Participants With Geographic Atrophy
NCT04465955
Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)
NCT04210245
Study of Aldafermin (NGM282) in Participants With Impaired Renal Function
NCT04179630
Study of NGM120 in Subjects With Advanced Solid Tumors, Pancreatic Cancer, and Prostate Cancer Using Combination Therapy
NCT04068896
Study of NGM621 in Participants With Geographic Atrophy
NCT04014777
Evaluation of Efficacy, Safety and Tolerability of Aldafermin in a Phase 2b, Randomized, Double-blind, Placebo-controlled, Multi-center Study In Subjects With Nonalcoholic Steatohepatitis and Stage 2/3 Fibrosis (ALPINE 2/3)
NCT03912532
Study of NGM313 in Obese Participants
NCT03298464
A Study of NGM282 in Patients With Primary Sclerosing Cholangitis
NCT02704364
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
NCT02649062
Study of NGM282 in Patients With Nonalcoholic Steatohepatitis (NASH)
NCT02443116
Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis
NCT02135536
Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis
NCT02026401
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 8 |
What the Pipeline for NGM Biopharmaceuticals Shows
According to the ClinicalTrials.gov registry, NGM Biopharmaceuticals is linked to 18 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 14 are already marked complete, representing roughly 78% of the total.
The phase mix for NGM Biopharmaceuticals reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 18 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for NGM Biopharmaceuticals is Squamous Cell Carcinoma of Head and Neck with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.