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NCT04557969 · ClinicalTrials.gov registry record
Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
A clinical trial of Gastric Cancer and Gastrointestinal Stromal Tumor (GIST), sponsored by National Cancer Institute (NCI).
- Recruiting
- Registry status
- 400
- Enrollment target
- 1
- Study location
NCT04557969: Recruiting study of Gastric Cancer and Gastrointestinal Stromal Tumor (GIST), sponsored by National Cancer Institute (NCI).
NCT04557969 is a study of Gastric Cancer and Gastrointestinal Stromal Tumor (GIST) that is actively recruiting participants, run by National Cancer Institute (NCI). The registered enrollment target is 400 participants, above the 317-participant average among 153 other Gastric Cancer trials with a reported enrollment target (26% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04557969, a study of Gastric Cancer and Gastrointestinal Stromal Tumor (GIST), is actively recruiting participants, sponsored by National Cancer Institute (NCI).
- RECRUITING
- Registry status
- 400 participants
- Enrollment target
- 1
- Study location
Study Summary
Objective: To follow people with GISTs and collect tumor tissue so that it can be studied in the lab. Eligibility: People age 6 and older who have a GIST. Design: Participants will be screened with a review of their medical records and samples. Participants will enroll in 1 other NIH study, and may be asked to enroll in 2 other optional NIH studies. Participants will have a medical history and physical exam. Data about how they function in their daily activities will be obtained. Participants may speak with a genetic counselor. They may have genetic testing. Participants will give blood samples. They may have a cheek swab. For this, small brush will be rubbed against the inside of the cheek. Participants may have a computed tomography (CT) scan of the chest, abdomen, and pelvis. Or they may have a CT scan of the chest and magnetic resonance imaging (MRI) of the abdomen and pelvis. Participants will be monitored every 6-12 months at the NIH Clinical Center, for up to 10 years before having surgery. If they need surgery, it will be performed at the NIH. Then, they will be monitored every 6-12 months, for up to 5 years after surgery. If a participant has surgery, tumor tissue samples and research specimen will be taken. If a participant does not need surgery, their participation will end after 10 years. If they have surgery, the 5-year monitoring period will restart after each surgery.
Primary Outcome
Patients with non-WT GIST and WT GIST will have the durations of the DFIs described both within each patient as their own control and across patients. Analyses will be done separately for those with WT GIST and those with non-WT GIST as well as for all patients combined.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 400 participants |
| Start Date | 2020-12-18 |
| Est. Completion | 2040-12-30 |
What NCT04557969 shows while recruiting
NCT04557969 is an observational study that tracks outcomes without assigning an intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, above the 317-participant average among 153 other Gastric Cancer trials with a reported enrollment target (26% higher).
The record links to 5 conditions, with Gastric Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT04557969 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04557969 about?
NCT04557969 is a clinical study titled "Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis". Objective: To follow people with GISTs and collect tumor tissue so that it can be studied in the lab. Eligibility: People age 6 and older who have a GIST. Design: Participants will be screened with a review of their medical records and samples. Participants will enroll in 1 other NIH study, an...
What is the current status of trial NCT04557969?
This trial is currently recruiting. The enrollment target is 400 participants. The study started on 2020-12-18. Estimated completion is 2040-12-30.
What conditions does trial NCT04557969 study?
This clinical trial studies the following conditions: Gastric Cancer, Gastrointestinal Stromal Tumor (GIST), Gastric Neoplasm, Gastrointestinal Stromal Neoplasm, Gastrointestinal Stromal Sarcoma.
Who is sponsoring clinical trial NCT04557969?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04557969 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04557969's enrollment target sits among peer trials
400 33rd of 153 higher than 121 of 153 other Gastric Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gastric Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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