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ClinicalTrials.gov 72 recruiting now official registry

Gastric Cancer clinical trials

72 of 159 indexed Gastric Cancer trials are currently recruiting.

159 US clinical trials · 72 currently recruiting

Gastric Cancer is the subject of 159 registered US clinical trials on ClinicalTrials.gov, 72 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 118 in Phase 1-2 (earlier-stage). The most active sponsor is AstraZeneca, running 11 of these trials.

The research picture

Gastric Cancer has 159 registered US clinical trials, 72 of them open to new participants right now, about 45% of the total.

72
recruiting participants now
45%
of trials open to enrollment
17
in Phase 3–4 (later-stage)
11
top sponsor: AstraZeneca
Phase 169Phase 249Phase 313Phase 44

Active & Recent Trials

159 total, page 2 of 4

RECRUITING Phase 1 100 participants

Study to Assess the Safety, Tolerability, and Efficacy of IDX-1197 in Combination with XELOX or Irinotecan in Patients with Advanced Gastric Cancer

Idience Co.

NCT04725994

RECRUITING 100 participants

CTNNA1 Familial Expansion Study

Abramson Cancer Center at Penn Medicine

NCT05126290

RECRUITING Phase 1 96 participants

A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas

Dren Bio

NCT06999187

RECRUITING Phase 1 78 participants

IDOV-Immune for Advanced Solid Tumors

ViroMissile

NCT06910657

RECRUITING Phase 1 71 participants

[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications

Blue Earth Diagnostics

NCT07432633

RECRUITING NA 70 participants

CONFIRM: Magnetic Resonance Guided Radiation Therapy

Brigham and Women's Hospital

NCT04368702

RECRUITING Phase 1 70 participants

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

AstraZeneca

NCT06147037

RECRUITING Phase 1 66 participants

Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers

Lumicell

NCT02584244

RECRUITING Phase 1 60 participants

Study of CRX100 as Monotherapy and in Combination With Pembrolizumab in Patients With Advanced Solid Malignancies

BioEclipse Therapeutics

NCT04282044

RECRUITING Phase 2 58 participants

Novel SEQUEnced Immunotherapy With Anti-angiogenesis and Chemotherapy in Advanced gastroesophageaL Adenocarcinoma

Harry H Yoon

NCT04069273

RECRUITING Phase 2 54 participants

Combination of TATE and PD-1 Inhibitor in Liver Cancer

Teclison

NCT03259867

RECRUITING Phase 2 51 participants

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

University of California, Irvine

NCT06580002

RECRUITING Phase 1 45 participants

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors

Baylor College of Medicine

NCT03740256

RECRUITING Phase 1 42 participants

CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer

Washington University School of Medicine

NCT05187182

RECRUITING Phase 2 36 participants

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT06109467

RECRUITING Phase 1 30 participants

KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer

Christian Hinrichs

NCT05483491

RECRUITING Phase 1 27 participants

A Study of MT-4561 in Patients With Various Advanced Solid Tumors

Tanabe Pharma America

NCT06943521

RECRUITING Phase 2 27 participants

Avutometinib and Defactinib in Diffuse Gastric Cancer

Ryan H. Moy, MD, PhD

NCT06487221

RECRUITING Phase 1 26 participants

64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

Lantheus Medical Imaging

NCT06298916

RECRUITING Phase 2 21 participants

Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric Cancer

University of Chicago

NCT04107077

RECRUITING Phase 1 18 participants

Neratinib and Fam-Trastuzumab Deruxtecan in Advanced Gastro-esophageal Cancer Patients

Fox Chase Cancer Center

NCT05274048

RECRUITING Phase 4 15 participants

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

Cedars-Sinai Medical Center

NCT07124351

ACTIVE NOT RECRUITING 6,000 participants

Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract

Memorial Sloan Kettering Cancer Center

NCT00582647

ACTIVE NOT RECRUITING Phase 1 914 participants

Study of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid Tumors

Exelixis

NCT03170960

ACTIVE NOT RECRUITING Phase 1 702 participants

Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies

AstraZeneca

NCT04644068

ACTIVE NOT RECRUITING Phase 3 547 participants

Bemarituzumab or Placebo Plus Chemotherapy in Gastric Cancers With Fibroblast Growth Factor Receptor 2b (FGFR2b) Overexpression

Amgen

NCT05052801

ACTIVE NOT RECRUITING Phase 3 515 participants

Bemarituzumab Plus Chemotherapy and Nivolumab Versus Chemotherapy and Nivolumab for FGFR2b Overexpressed Untreated Advanced Gastric and Gastroesophageal Junction Cancer.

Amgen

NCT05111626

ACTIVE NOT RECRUITING Phase 4 500 participants

Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community- AIM 1

University of Miami

NCT07224035

ACTIVE NOT RECRUITING Phase 1 352 participants

Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors

M.D. Anderson Cancer Center

NCT05075993

ACTIVE NOT RECRUITING Phase 1 296 participants

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Inhibrx Biosciences

NCT04198766

ACTIVE NOT RECRUITING Phase 1 194 participants

Phase 1/2 Study Evaluating MCLA-129, a Human Anti-EGFR, Anti-c-MET Bispecific Antibody, in Advanced NSCLC and Other Solid Tumors, Alone and in Combination

Merus B.V.

NCT04868877

ACTIVE NOT RECRUITING Phase 1 180 participants

P-MUC1C-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Advanced or Metastatic Solid Tumors

Poseida Therapeutics

NCT05239143

ACTIVE NOT RECRUITING Phase 1 179 participants

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

NGM Biopharmaceuticals

NCT04913337

ACTIVE NOT RECRUITING Phase 1 163 participants

First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer

TORL Biotherapeutics

NCT05156866

ACTIVE NOT RECRUITING Phase 1 150 participants

A Trial to Evaluate Safety and Tolerability of TST001 in Advanced or Metastatic Solid Tumors

Suzhou Transcenta Therapeutics Co.

NCT04396821

ACTIVE NOT RECRUITING Phase 2 143 participants

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

Astellas Pharma Global Development

NCT03505320

ACTIVE NOT RECRUITING Phase 1 138 participants

A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors

Toray Industries

NCT03872947

ACTIVE NOT RECRUITING Phase 1 136 participants

A Study to Assess the Safety and Efficacy of AZD7789 in Participants With Advanced or Metastatic Solid Cancer

AstraZeneca

NCT04931654

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors

Cybrexa Therapeutics

NCT04902872

ACTIVE NOT RECRUITING Phase 1 130 participants

Study of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid Tumors

NGM Biopharmaceuticals

NCT05215574

ACTIVE NOT RECRUITING Phase 2 127 participants

A Study of Evorpacept (ALX148) in Patients With Advanced HER2+ Gastric Cancer (ASPEN-06)

ALX Oncology

NCT05002127

ACTIVE NOT RECRUITING Phase 1 120 participants

Oral Axl/Mer/CSF1R Selective Tyrosine Kinase Inhibitor Q702 in Combination With Pembrolizumab in Patients With Selected Advanced Solid Tumors

Qurient Co.

NCT05438420

ACTIVE NOT RECRUITING Phase 1 110 participants

Claudin18.2 CAR-T (CT041) in Patients with Gastric, Pancreatic Cancer, or Other Specified Digestive Cancers

CARsgen Therapeutics Co.

NCT04404595

ACTIVE NOT RECRUITING NA 107 participants

RCT of Mobile Apps & FitBit v. Usual Care

Weill Medical College of Cornell University

NCT03623464

ACTIVE NOT RECRUITING Phase 1 102 participants

A Study to Evaluate Safety, Pharmacokinetics, & Activity of RO7496353 in Combination With a Checkpoint Inhibitor With or Without Standard-of-care Chemotherapy in Participants With Locally Advanced or Metastatic Solid Tumors; Urothelial Carcinoma Substudy in Association With RO7496353 Study GO44010

Genentech

NCT05867121

ACTIVE NOT RECRUITING Phase 1 98 participants

A Study of SNS-101 (Anti VISTA) Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Sensei Biotherapeutics

NCT05864144

ACTIVE NOT RECRUITING Phase 1 97 participants

A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants with Advanced Unresectable or Metastatic Solid Tumors

NextCure

NCT05572684

ACTIVE NOT RECRUITING Phase 1 83 participants

A Study of HFB200603 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

HiFiBiO Therapeutics

NCT05789069

ACTIVE NOT RECRUITING Phase 4 75 participants

Helicobacter Pylori Screening and Treatment in the At-risk South Florida Community-AIM 2

University of Miami

NCT07224048

ACTIVE NOT RECRUITING Phase 1 72 participants

A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors

HiFiBiO Therapeutics

NCT05238883

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Phase Distribution

PhaseTrial count
Phase 1 69
Phase 2 49
Phase 3 13
Phase 4 4

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Gastric Cancer Trial Landscape

159 indexed Gastric Cancer studies · 72 recruiting (45%).

Phase mix: 17 late (III/IV) vs 118 early (I/II).

Top sponsor: AstraZeneca (11 trials), 9 others listed. 50 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Gastric Cancer?

PlainTrial tracks 159 US clinical trials for Gastric Cancer, of which 72 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Gastric Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.