Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Neoplasms

Open-data reference.

160 US clinical trials · 50 currently recruiting

Active & Recent Trials

RECRUITING 100,000 participants

AnovaOS Network Powered Patient Registry

Anova Enterprises

NCT05013944

RECRUITING 50,000 participants

RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT

The Radiosurgery Society

NCT01885299

RECRUITING 40,000 participants

Registry Study for Radiation Therapy Outcomes

Proton Collaborative Group

NCT01255748

RECRUITING 15,000 participants

Cancer Experience Registry (CER) for Cancer Patients and Caregivers

Cancer Support Community, Research and Training Institute, Philadelphia

NCT02333604

RECRUITING 6,000 participants

Collection of Tissue Specimens From Patients With Solid Tumors or Blood Disorders and Their HLA-Compatible Family Members

National Heart, Lung, and Blood Institute (NHLBI)

NCT00071045

RECRUITING 5,000 participants

Clinical and Genetic Studies of Li-Fraumeni Syndrome

National Cancer Institute (NCI)

NCT01443468

RECRUITING 5,000 participants

Collection of Tissue Samples for Cancer Research

National Cancer Institute (NCI)

NCT00900198

RECRUITING 3,000 participants

Real World Registry for Use of the Ion Endoluminal System

Intuitive Surgical

NCT06004440

RECRUITING 3,000 participants

Sample Collection and Tracking for the Developmental Therapeutics Clinic

National Cancer Institute (NCI)

NCT03269578

RECRUITING 2,000 participants

Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy

Stanford University

NCT00349830

RECRUITING Phase 2 1,541 participants

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

Celgene

NCT03435796

RECRUITING NA 1,500 participants

Biennial CEM in Women With a Personal History of Breast Cancer

Wendie Berg

NCT06105749

RECRUITING NA 610 participants

Serious Gaming for Chemotherapy-induced Nausea and Vomiting

University of Central Florida

NCT05838638

RECRUITING Phase 1 590 participants

A Study of GSK5764227 in Participants With. Advanced Solid Tumors (EMBOLD PanTumor-101)

GlaxoSmithKline

NCT06551142

RECRUITING 500 participants

AIMS Cancer Outcomes Study

Advanced Integrative Medical Science Institute

NCT04495790

RECRUITING NA 500 participants

Screening Strategies Among High-risk Populations for Anal Cancer

Lisa Flowers

NCT06628570

RECRUITING Phase 1 385 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT06431594

RECRUITING Phase 1 365 participants

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Marengo Therapeutics

NCT05592626

RECRUITING Phase 1 345 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

Hoffmann-La Roche

NCT06884618

RECRUITING Phase 1 276 participants

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-021 in Patients With Advanced Solid Tumor

Abbisko Therapeutics Co

NCT04192344

RECRUITING Phase 1 252 participants

Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617

Pathos AI

NCT06785636

RECRUITING Phase 1 250 participants

Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

USWM CT

NCT03391778

RECRUITING Phase 1 220 participants

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Janssen Research & Development

NCT06150157

RECRUITING Phase 2 204 participants

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

Eli Lilly and Company

NCT07169851

RECRUITING Phase 1 200 participants

A Study of JNJ-87890387 for Advanced Solid Tumors

Janssen Research & Development

NCT06178614

RECRUITING Phase 1 152 participants

EMB-01 in Patients With Advanced/Metastatic Gastrointestinal Cancers

Shanghai EpimAb Biotherapeutics Co.

NCT05176665

RECRUITING 150 participants

Barrett's Esophagus Related Neoplasia (BERN) Project

Midwest Biomedical Research Foundation

NCT00590239

RECRUITING Phase 2 140 participants

A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors

EpicentRx

NCT04673942

RECRUITING Phase 2 105 participants

A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

Eli Lilly and Company

NCT05999994

RECRUITING Phase 1 100 participants

Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

National Cancer Institute (NCI)

NCT06885697

RECRUITING Phase 2 96 participants

Take the Reins: The Effects of Nutrient Timing on Cancer-related Fatigue

University of Maryland, Baltimore

NCT06482515

RECRUITING Phase 1 96 participants

A Study of JNJ-87704916, as Monotherapy and in Combination for Advanced Solid Tumors

Johnson & Johnson Enterprise Innovation

NCT06311578

RECRUITING 84 participants

Resilience in East Asian Immigrants for Advance Care Planning Discussions

University of Illinois at Chicago

NCT06035549

RECRUITING Phase 1 84 participants

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT07277270

RECRUITING Phase 2 82 participants

Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

National Cancer Institute (NCI)

NCT04449549

RECRUITING Phase 1 81 participants

A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

OriCell Therapeutics Co.

NCT06271252

RECRUITING NA 80 participants

Endometrial Cell Collection With the PadKit

Hackensack Meridian Health

NCT06464107

RECRUITING Phase 1 73 participants

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Stemline Therapeutics

NCT05386108

RECRUITING Phase 1 65 participants

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT03366116

RECRUITING NA 60 participants

Bladder Fiducial Markers and Multiparametric-MRI (Mp-MRI) to Optimize Bladder Chemo-radiotherapy

Cedars-Sinai Medical Center

NCT04442724

RECRUITING Phase 1 50 participants

Two Part Study of Nenocorilant Combined With Nivolumab in Patients With Advanced Solid Malignancies

Corcept Therapeutics

NCT07276373

RECRUITING Phase 1 50 participants

Safety of SBRT With Anti-PD1 and Anti-IL-8 for the Treatment of Multiple Metastases in Advanced Solid Tumors and Melanoma

Yana Najjar

NCT04572451

RECRUITING Phase 1 47 participants

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

GlaxoSmithKline

NCT07213609

RECRUITING Phase 1 41 participants

A Study of [18F]LY4214835 in Healthy Volunteers and Participants With Cancer

Eli Lilly and Company

NCT07258836

RECRUITING NA 35 participants

Mobile Health Intervention to Improve Adherence to Oral Anticancer Therapy

University of California, Irvine

NCT07073807

RECRUITING Phase 1 33 participants

Phase 1 Study of JV-394 Autologous Anti-CD94 CAR T for r/r CD94+ T/NK Cell Neoplasms

M.D. Anderson Cancer Center

NCT07382817

RECRUITING NA 32 participants

LITT Followed by Hypofractionated RT for Recurrent Gliomas

University of Maryland, Baltimore

NCT04181684

RECRUITING Phase 1 24 participants

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

M.D. Anderson Cancer Center

NCT03911388

RECRUITING 20 participants

Feasibility of Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors

Cedars-Sinai Medical Center

NCT05391217

RECRUITING Phase 4 15 participants

18F-Fluciclovine PET/CT Impact on Predicting Clinical Outcome of 177Lu-PSMA-617 Therapy in Patients With Prostate Cancer

VA Greater Los Angeles Healthcare System

NCT06706921

ACTIVE NOT RECRUITING NA 1,647 participants

Tomosynthesis vs. Contrast-Enhanced Mammography in Women With Personal History of Breast Cancer in Western Pennsylvania

Wendie Berg

NCT04085510

ACTIVE NOT RECRUITING Phase 3 831 participants

A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer

Pfizer

NCT04607421

ACTIVE NOT RECRUITING Phase 3 785 participants

A Study to Evaluate Dostarlimab Plus Carboplatin-paclitaxel Versus Placebo Plus Carboplatin-paclitaxel in Participants With Recurrent or Primary Advanced Endometrial Cancer

Tesaro

NCT03981796

ACTIVE NOT RECRUITING Phase 1 730 participants

Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors

Tesaro

NCT02715284

ACTIVE NOT RECRUITING Phase 1 463 participants

A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)

Tesaro

NCT02817633

ACTIVE NOT RECRUITING Phase 1 413 participants

A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of JNJ-63723283, an Anti-PD-1 Monoclonal Antibody, in Participants With Advanced Cancers

Janssen Research & Development

NCT02908906

ACTIVE NOT RECRUITING Phase 1 301 participants

A Study of E7386 in Combination With Other Anticancer Drug(s) in Participants With Solid Tumor

Eisai

NCT04008797

ACTIVE NOT RECRUITING Phase 3 300 participants

Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation

Alliance for Clinical Trials in Oncology

NCT04711109

ACTIVE NOT RECRUITING Phase 2 237 participants

Extended Access of Momelotinib in Adults With Myelofibrosis

GlaxoSmithKline

NCT03441113

ACTIVE NOT RECRUITING 232 participants

M7824 Related Adverse Effects in Adults With Cancer

National Cancer Institute (NCI)

NCT04267861

ACTIVE NOT RECRUITING Phase 3 200 participants

A Rollover Study of Alectinib in Patients With Anaplastic Lymphoma Kinase (ALK)-Positive or Rearranged During Transfection (RET)-Positive Cancer

Hoffmann-La Roche

NCT03194893

ACTIVE NOT RECRUITING Phase 1 158 participants

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Janssen Research & Development

NCT04606381

ACTIVE NOT RECRUITING Phase 1 152 participants

First-Time-in-Human Study of GSK4381562 in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT05277051

ACTIVE NOT RECRUITING Phase 1 151 participants

A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer

Boehringer Ingelheim

NCT04958239

ACTIVE NOT RECRUITING Phase 2 120 participants

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Aadi Bioscience

NCT05103358

ACTIVE NOT RECRUITING Phase 1 107 participants

Study of the Safety and Effectiveness of GSK6097608 in Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT04446351

ACTIVE NOT RECRUITING Phase 2 103 participants

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

USWM CT

NCT03967223

ACTIVE NOT RECRUITING Phase 1 97 participants

A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors

GlaxoSmithKline

NCT03843359

ACTIVE NOT RECRUITING Phase 2 87 participants

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Treated Advanced (Metastatic or Unresectable) Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

USWM CT

NCT06703346

ACTIVE NOT RECRUITING 80 participants

Digitally-Captured Step Counts for Evaluating Performance Status in Advanced Cancer Patients

Cedars-Sinai Medical Center

NCT03757182

ACTIVE NOT RECRUITING NA 58 participants

Hispanic Adapted and Culturally Relevant Exercising Together

University of Arizona

NCT06018311

ACTIVE NOT RECRUITING NA 50 participants

Time-Restricted Eating to Address Persistent Cancer-Related Fatigue

University of Maryland, Baltimore

NCT05256888

ACTIVE NOT RECRUITING Phase 1 43 participants

Study of CAR-T Cells Expressing CD30 and CCR4 for r/r CD30+ HL and CTCL

UNC Lineberger Comprehensive Cancer Center

NCT03602157

ACTIVE NOT RECRUITING Phase 1 42 participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

GlaxoSmithKline

NCT06077877

ACTIVE NOT RECRUITING Phase 1 38 participants

Study of CD30 CAR for Relapsed/Refractory CD30+ HL and CD30+ NHL

UNC Lineberger Comprehensive Cancer Center

NCT02690545

ACTIVE NOT RECRUITING Phase 2 21 participants

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

National Cancer Institute (NCI)

NCT05797246

ACTIVE NOT RECRUITING Phase 1 18 participants

Administration of T Lymphocytes for Prevention of Relapse of Lymphomas

UNC Lineberger Comprehensive Cancer Center

NCT02663297

ACTIVE NOT RECRUITING Phase 2 7 participants

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

USWM, LLC (dba US WorldMeds)

NCT05993299

COMPLETED 1,400 participants

Concordance Between ctDNA Assay and FoundationOne

Foundation Medicine

NCT02620527

COMPLETED Phase 3 866 participants

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)

Celgene

NCT01964430

COMPLETED Phase 3 755 participants

XRP6258 Plus Prednisone Compared to Mitoxantrone Plus Prednisone in Hormone Refractory Metastatic Prostate Cancer

Sanofi

NCT00417079

COMPLETED Phase 1 610 participants

A Study to Assess the Safety and Pharmacokinetics of MOXR0916 and Atezolizumab (Also Known as MPDL3280A or Anti-PD-L1) in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT02410512

COMPLETED Phase 2 440 participants

REST: Reducing End-of-Life Symptoms With Touch

National Center for Complementary and Integrative Health (NCCIH)

NCT00065195

COMPLETED NA 358 participants

Enhanced Self-Efficacy Training

Duke University

NCT00938769

COMPLETED 300 participants

Views of Cancer Patients Regarding Financial Conflicts of Interest

National Institutes of Health Clinical Center (CC)

NCT00097682

COMPLETED Phase 1 266 participants

This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)

Boehringer Ingelheim

NCT03449381

COMPLETED NA 258 participants

Addressing Cancer-Related Financial Toxicity in Rural Oncology Care Settings

UNC Lineberger Comprehensive Cancer Center

NCT04931251

COMPLETED 242 participants

Human Leukocyte Antigen Typing and Tumor Antigen Expression Profiling

Immatics US

NCT03760952

COMPLETED Phase 1 236 participants

Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule

Tesaro

NCT03329001

COMPLETED Phase 1 229 participants

A Study of LY2880070 in Participants With Advanced or Metastatic Cancer

Esperas Pharma

NCT02632448

COMPLETED Phase 3 221 participants

Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy

Norwegian University of Science and Technology

NCT02330926

COMPLETED 214 participants

Combined F-18 NaF and F-18 FDG PET/CT for Evaluation of Malignancy

Stanford University

NCT00725387

COMPLETED Phase 1 174 participants

A Study to Assess Safety and Pharmacokinetics of MOXR0916 in Participants With Locally Advanced or Metastatic Solid Tumors

Genentech

NCT02219724

COMPLETED Phase 1 170 participants

A Study in Metastatic Cancer and Advanced or Metastatic Unresectable Pancreatic Cancer

Eli Lilly and Company

NCT01373164

COMPLETED NA 154 participants

Outlook: An Intervention to Improve Quality of Life in Serious Illness

Duke University

NCT00939146

COMPLETED NA 140 participants

Exercise Intervention for LGBT Cancer Survivors

University of Rochester

NCT02459769

COMPLETED Phase 1 138 participants

A Study Of PF-06647020 For Adult Patients With Advanced Solid Tumors

Pfizer

NCT02222922

COMPLETED Phase 1 133 participants

This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer

Boehringer Ingelheim

NCT03099174

COMPLETED NA 123 participants

A Treatment Protocol For Patients Continuing From A Prior SU011248 Protocol.

Pfizer

NCT00443534

COMPLETED 121 participants

Livestrong Cancer Institutes' Patient Reported Outcomes Study

University of Texas at Austin

NCT04627077

Phase Distribution

PhaseTrial count
Early Phase 1 81
Phase 2 18
Phase 3 7
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Neoplasms Trial Landscape

ClinicalTrials.gov lists 160 US studies indexed under Neoplasms, and 50 of those are currently open to recruitment — roughly 31% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Neoplasms shows 9 late-stage studies (Phase 3 and Phase 4 combined) alongside 99 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Neoplasms is led by National Cancer Institute (NCI) with 15 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Neoplasms?

PlainTrial tracks 160 US clinical trials for Neoplasms, of which 50 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Neoplasms?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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