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NCT04600466 · ClinicalTrials.gov registry record
Molecular and Epidemiological Risk Factors in the Development of Gastric Cancer
A clinical trial of Gastric Cancer, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- 150
- Enrollment target
- 1
- Study location
NCT04600466: Recruiting study of Gastric Cancer, sponsored by The University of Texas Health Science Center at San Antonio.
NCT04600466 is a study of Gastric Cancer that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 150 participants, below the 318-participant average among 153 other Gastric Cancer trials with a reported enrollment target (53% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04600466, a study of Gastric Cancer, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- 150 participants
- Enrollment target
- 1
- Study location
Study Summary
This protocol is a single-institution feasibility study to identify the molecular and epidemiological risk factors in the development of gastric cancer in high-risk predominantly Hispanic South Texas population. The study is broken down into two main parts: 1) To identify molecular differences in gastric adenocarcinoma (GAC) between Non-Hispanics and Hispanics, stratified by age, and in benign, pre-malignant, and malignant gastric lesions; and 2) To identify environmental and clinicopathological factors in Hispanics associated with specific molecular changes linked to the development of GAC.
Primary Outcome
DNA from archived FFPE gastric cancer tissue from patients with diagnosis of GAC will be analyzed for the top 25 mutated genes identified in The Cancer Genome Atlas. The results will be compared and analyzed between Hispanics and non-Hispanics. In addition, germline testing using a 156 gene panel using saliva will be performs on patients with GAC and compared between Hispanics and non-Hispanics. Difference in somatic and germline mutations will be analyzed in patients with GAC between Hispanics
Conditions Studied
Interventions
- OTHER Survey
- OTHER Molecular testing for all participants.
- OTHER Germline Testing
Study Locations (1)
Texas
- Mays Cancer Center, UT Health San Antonio - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2021-01-22 |
| Est. Completion | 2030-01-22 |
What NCT04600466 shows while recruiting
NCT04600466 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 318-participant average among 153 other Gastric Cancer trials with a reported enrollment target (53% lower).
The record links to 1 condition, with Gastric Cancer appearing as the primary indexed condition, and to 3 interventions - of which Survey is the first listed.
NCT04600466 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04600466 about?
NCT04600466 is a clinical study titled "Molecular and Epidemiological Risk Factors in the Development of Gastric Cancer". This protocol is a single-institution feasibility study to identify the molecular and epidemiological risk factors in the development of gastric cancer in high-risk predominantly Hispanic South Texas population. The study is broken down into two main parts: 1) To identify molecular differences in ga...
What is the current status of trial NCT04600466?
This trial is currently recruiting. The enrollment target is 150 participants. The study started on 2021-01-22. Estimated completion is 2030-01-22.
What conditions does trial NCT04600466 study?
This clinical trial studies the following conditions: Gastric Cancer.
What interventions are being tested in trial NCT04600466?
The interventions under investigation include: Survey (OTHER), Molecular testing for all participants. (OTHER), Germline Testing (OTHER).
Who is sponsoring clinical trial NCT04600466?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04600466 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gastric Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04600466's enrollment target sits among peer trials
150 61st of 153 higher than 92 of 153 other Gastric Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gastric Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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