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NCT06710756 · ClinicalTrials.gov registry record · Phase 1

Lead-212 PSV359 Therapy for Patients With Solid Tumors

A Phase 1 study of Colorectal Cancer and Ovarian Cancer, sponsored by Perspective Therapeutics.

Recruiting
Registry status
Phase 1
Development phase
112
Enrollment target
3
Study locations

NCT06710756 is a Phase 1 study of Colorectal Cancer and Ovarian Cancer that is actively recruiting participants, run by Perspective Therapeutics. The registered enrollment target is 112 participants, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (93% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT06710756, a Phase 1 study of Colorectal Cancer and Ovarian Cancer, is actively recruiting participants, sponsored by Perspective Therapeutics.

RECRUITING
Registry status
Phase 1
Development phase
112 participants
Enrollment target
3
Study locations

Study Summary

Phase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation Protein (FAP)-positive.

Interventions

  • DRUG [203Pb]Pb-PSV359
  • DRUG [212Pb]Pb-PSV359

Study Locations (3)

Missouri

  • Saint Louis University - St Louis

Nebraska

  • Nebraska Cancer Specialists - Omaha

Pennsylvania

  • University of Pittsburgh Medical Center - Pittsburgh

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 2025-04-28
Est. Completion 2032-05-28
Phase Phase 1

Sponsor

Perspective Therapeutics

4 total trials

What the Registry Record Tells You About NCT06710756

The ClinicalTrials.gov registry entry for NCT06710756 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 112 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,511-participant average among 369 other Colorectal Cancer trials with a reported enrollment target (93% lower). The listed sponsor is Perspective Therapeutics, which has 4 total studies on file at ClinicalTrials.gov.

The record links to 8 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 2 interventions - of which [203Pb]Pb-PSV359 is the first listed.

NCT06710756 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Missouri, Nebraska, Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT06710756 about?

NCT06710756 is a clinical study titled "Lead-212 PSV359 Therapy for Patients With Solid Tumors". Phase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation Protein (FAP)-positive.

What is the current status of trial NCT06710756?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 112 participants. The study started on 2025-04-28. Estimated completion is 2032-05-28.

What conditions does trial NCT06710756 study?

This clinical trial studies the following conditions: Colorectal Cancer, Ovarian Cancer, Head and Neck Cancer, Gastric Cancer, Esophageal Cancer.

What interventions are being tested in trial NCT06710756?

The interventions under investigation include: [203Pb]Pb-PSV359 (DRUG), [212Pb]Pb-PSV359 (DRUG).

Who is sponsoring clinical trial NCT06710756?

This trial is sponsored by Perspective Therapeutics, which has 4 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06710756 being conducted?

This trial has 3 study locations across Missouri, Nebraska, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.