Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Cardiovascular Diseases: full-pipeline trial registry
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
Corpus placement: #27 of 28,707 conditions by registered trial count.
304 US clinical trials · 134 currently recruiting · #27 of 28,707 conditions by registered trial count
Cardiovascular Diseases: 304 US clinical trials tracked, 134 recruiting.
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
Enrollment posture brief
Registry condition cardiovascular-diseases
OPEN 134 | RECR 44% | LATE 26 | EARLY 28 | RANK #27 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Suicide (44% recruiting · 93 trials)
Cardiovascular Diseases lists 134 open slots (44% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cardiovascular Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cardiovascular Diseases is recruiting above its size-band peers.
134 of 304 indexed trials (44.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cardiovascular Diseases trials is spread across many organizations.
Duke University accounts for 10 of 304 trials (3.3%). 159 distinct sponsors appear on at least one study for this condition label.
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Typical Cardiovascular Diseases enrolment sits around 200 participants.
Median target enrolment is 200 among the 301 trials that report a genuine target (sentinel values excluded). 101 of those (33.6%) plan for fewer than 100 participants.
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Cardiovascular Diseases research is mostly interventional.
225 interventional and 79 observational studies make up this index (74% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
304 total, page 2 of 7
SMART to Optimize an Intervention to Maintain Health Improvements After Cardiac Rehabilitation
The Miriam Hospital
NCT06886789
Structural Conditions and Health After Release From Prison
Kaiser Permanente
NCT05989282
Biopsy Collection and Repository Database
Kenneth S. Campbell
NCT05521503
TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
Brigham and Women's Hospital
NCT00985049
Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention
Ohio State University
NCT06055036
The PulsePoint Study
Dr. Steven Brooks
NCT04806958
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR
Cardiac Dimensions
NCT03142152
Gut Microbiota in Metabolic Surgery
Vanderbilt University Medical Center
NCT05000996
BLOOM: Biological Legacy of Origin in Mother-Infant Dyads
University of Miami
NCT02000895
Text Education About Cardiovascular Health and HIV (TEACH-HIV)
University of California, San Francisco
NCT05642858
Patient Care Outreach, Navigation, Technology and Support 2.0
University of California, San Francisco
NCT06648278
Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty
VA Office of Research and Development
NCT06244199
Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT
Vanderbilt University Medical Center
NCT05288790
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
Boston Children's Hospital
NCT05464186
NAUTICAL: Effect of Natriuretic Peptide Augmentation on Cardiometabolic Health in Black Individuals
University of Alabama at Birmingham
NCT04055428
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
University of Alabama at Birmingham
NCT05216042
Wellness Intervention for Smoking and HIV
University of Arizona
NCT04725617
Cardiovascular Risk Reduction for Adults With Food Insecurity Using Structured Incentives
State University of New York at Buffalo
NCT06818669
Techquity by FAITH!
Mayo Clinic
NCT06187077
Omega-3D: Omega-3 for Diet-Driven Health Disparities
University of Arizona
NCT07078344
PRimary IndividualiZed Evaluation of Cardiovascular Events in Patients With Diabetes Mellitus Using hemoTAG
Aventusoft
NCT06567795
CV CARE: CardioVascular Care in PC Patients
Dana-Farber Cancer Institute
NCT06202820
Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs
C5 Biomedical
NCT06674980
SPYRAL GEMINI Pilot Study
Medtronic Vascular
NCT06907147
Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder
University of California, Los Angeles
NCT05516277
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
University of Alabama at Birmingham
NCT04971720
Groceries for Residents of Southeastern USA to Stop Hypertension
Beth Israel Deaconess Medical Center
NCT06891911
CV Imaging of Metabolic Interventions
The Cleveland Clinic
NCT05650307
Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans
VA Office of Research and Development
NCT05423158
Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care
VA Office of Research and Development
NCT04877197
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
Wake Forest University Health Sciences
NCT06488105
NightWare and Cardiovascular Health in Veterans With PTSD
VA Office of Research and Development
NCT06419959
CLEANer Aspiration for Pulmonary Embolism
Argon Medical Devices
NCT06189313
Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
Priscilla Hsue, MD
NCT05488431
VicorderCS NIBP Validation Study to Review The Ability to Capture Blood Pressure Measurements
80 Beats Medical
NCT06560034
Exercise Activity Intervention With Sensor-Based Engagement in Patients With Atrial Fibrillation
Icahn School of Medicine at Mount Sinai
NCT06938412
EVOC - EVs in Obesity and Cardiometabolic Disease
Massachusetts General Hospital
NCT06408961
Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics
Washington University School of Medicine
NCT06397729
Home-Based Cardiac Rehabilitation for Patients With Heart Failure
Vanderbilt University Medical Center
NCT06479876
Secondhand Tobacco Smoke and Cardiovascular Disease
University of California, San Francisco
NCT04715568
The Cooking for Health Optimization and Disease Prevention (CHOP) Trial
Tulane University
NCT07011459
Initial Assessment of the Feasibility and Efficacy of a Scalable Digital CBT for Generalized Anxiety and Associated Health Behaviors in a Cardiovascular Disease Population
Boston University Charles River Campus
NCT04895995
Inspire HER: Inspiring the Heart and Emotions for Radical Health
University of Alabama at Birmingham
NCT06966258
A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study
OriCell Therapeutics Co.
NCT06271252
Effect of Empagliflozin on Left Atrial Function in Adults at Risk for Heart Failure
University of Minnesota
NCT06507657
Black Women's Life Experience On Cardiovascular Health Via Ongoing Monitoring
The University of Texas at Arlington
NCT06150989
Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention
Poudre Valley Health System
NCT05322876
Brain Connections for Arm Movement After Stroke
VA Office of Research and Development
NCT04286516
Cardiovascular Effects of a Healthy Dietary Pattern Containing Eggs
Penn State University
NCT06120400
Prevention of Progression of Prediabetes, Obesity and CV Risk
The University of Texas Health Science Center at San Antonio
NCT06446531
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on Cardiovascular Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cardiovascular Diseases trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cardiovascular Diseases page
304 registered trials, 134 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 134 Cardiovascular Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Duke University sponsors the most Cardiovascular Diseases trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Diseases condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.