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NCT05288790 · ClinicalTrials.gov registry record · Phase 2

Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT

A Phase 2 study of HIV Infections and Cardiovascular Diseases, sponsored by Vanderbilt University Medical Center.

Recruiting
Registry status
Phase 2
Development phase
250
Enrollment target
1
Study location

NCT05288790 is a Phase 2 study of HIV Infections and Cardiovascular Diseases that is actively recruiting participants, run by Vanderbilt University Medical Center. The registered enrollment target is 250 participants, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (44% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05288790, a Phase 2 study of HIV Infections and Cardiovascular Diseases, is actively recruiting participants, sponsored by Vanderbilt University Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
250 participants
Enrollment target
1
Study location

Study Summary

Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill containing healthy gut bacteria can increase the number good bacteria in the gut, lower levels of inflammation, and lower the risk of heart disease and death.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Probiotic

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 250 participants
Start Date 2023-09-18
Est. Completion 2027-02-28
Phase Phase 2

What the Registry Record Tells You About NCT05288790

The ClinicalTrials.gov registry entry for NCT05288790 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 250 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 445-participant average among 542 other HIV Infections trials with a reported enrollment target (44% lower). The listed sponsor is Vanderbilt University Medical Center, which has 677 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with HIV Infections appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT05288790 reports 1 study location spanning 1 distinct geographic area - top geographies include Tennessee.

Frequently Asked Questions

What is clinical trial NCT05288790 about?

NCT05288790 is a clinical study titled "Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT". Among people living with HIV, heavy drinking increases the risk of heart disease and death. Studies suggest that alcohol changes the number and kind of bacteria in your gut and these changes increase the risk of heart disease and death. This randomized controlled trial will determine whether a pill ...

What is the current status of trial NCT05288790?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 250 participants. The study started on 2023-09-18. Estimated completion is 2027-02-28.

What conditions does trial NCT05288790 study?

This clinical trial studies the following conditions: HIV Infections, Cardiovascular Diseases, Alcohol Drinking, Dysbiosis, Microtia.

What interventions are being tested in trial NCT05288790?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Probiotic (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT05288790?

This trial is sponsored by Vanderbilt University Medical Center, which has 677 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05288790 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.