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NCT05216042 · ClinicalTrials.gov registry record · NA
GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study
A NA study of Obesity and Cardiovascular Diseases, sponsored by University of Alabama at Birmingham.
- Recruiting
- Registry status
- NA
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT05216042 is a NA study of Obesity and Cardiovascular Diseases that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 200 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05216042, a NA study of Obesity and Cardiovascular Diseases, is actively recruiting participants, sponsored by University of Alabama at Birmingham.
- RECRUITING
- Registry status
- NA
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes and poor cardiometabolic health. Obese and Black individuals have \~30% lower levels of NP and are at a greater risk of developing cardiovascular (CV) events as compared to lean and White counterparts. Some people have common genetic variations that cause them to have \~20% lower NP levels. Similar to other low NP populations, these individuals with low NP genotype (i.e., carrying a common genetic variation called rs5068) are at a greater risk of developing cardiometabolic diseases. By understanding the NP response following the exercise challenge and the glucose challenge in individuals with genetically lower NP levels will help us understand how to improve cardiometabolic health in them.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Study diet
- OTHER Exercise capacity VO2 max determination
- OTHER Exercise Challenge
- OTHER Glucose Challenge
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2022-04-01 |
| Est. Completion | 2027-04-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05216042
The ClinicalTrials.gov registry entry for NCT05216042 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (76% lower). The listed sponsor is University of Alabama at Birmingham, which has 1,160 total studies on file at ClinicalTrials.gov.
The record links to 7 conditions, with Obesity appearing as the primary indexed condition, and to 4 interventions - of which Study diet is the first listed.
NCT05216042 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT05216042 about?
NCT05216042 is a clinical study titled "GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study". Natriuretic Peptides (NP) are hormones produced by the heart, and they have a wide range of favorable metabolic benefits. Lower levels of these hormones are associated with an increased likelihood of the development of diabetes and poor cardiometabolic health. Obese and Black individuals have \~30% ...
What is the current status of trial NCT05216042?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2022-04-01. Estimated completion is 2027-04-30.
What conditions does trial NCT05216042 study?
This clinical trial studies the following conditions: Obesity, Cardiovascular Diseases, Exercise, Energy Expenditure, Glucose Metabolism.
What interventions are being tested in trial NCT05216042?
The interventions under investigation include: Study diet (DIETARY_SUPPLEMENT), Exercise capacity VO2 max determination (OTHER), Exercise Challenge (OTHER), Glucose Challenge (OTHER).
Who is sponsoring clinical trial NCT05216042?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05216042 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.