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NCT00985049 · ClinicalTrials.gov registry record
TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
A clinical trial of Cardiovascular Diseases, sponsored by Brigham and Women's Hospital.
- Recruiting
- Registry status
- 350
- Enrollment target
- 1
- Study location
NCT00985049: Recruiting study of Cardiovascular Diseases, sponsored by Brigham and Women's Hospital.
NCT00985049 is a study of Cardiovascular Diseases that is actively recruiting participants, run by Brigham and Women's Hospital. The registered enrollment target is 350 participants, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00985049, a study of Cardiovascular Diseases, is actively recruiting participants, sponsored by Brigham and Women's Hospital.
- RECRUITING
- Registry status
- 350 participants
- Enrollment target
- 1
- Study location
Study Summary
Hypothesis: The investigators hypothesize that genetic variants will alter gene expression in response to ischemia during cardiopulmonary bypass. To test this, the investigators will be taking small pieces of heart tissue from patients undergoing heart surgery before and after this period of ischemia. This will be compared to blood gene expression in blood cells and analyzed with the patients' genetic profile. This might allow us to assess the amount of inflammation that occurs when patients are on the heart-lung machine as well as examine the effects genes have on this critical time period.
Conditions Studied
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 350 participants |
| Start Date | 2009-03 |
| Est. Completion | 2025-12 |
What NCT00985049 shows while recruiting
NCT00985049 is an observational study that tracks outcomes without assigning an intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 26,973-participant average among 300 other Cardiovascular Diseases trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Cardiovascular Diseases appearing as the primary indexed condition, and to 0 interventions.
NCT00985049 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT00985049 about?
NCT00985049 is a clinical study titled "TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)". Hypothesis: The investigators hypothesize that genetic variants will alter gene expression in response to ischemia during cardiopulmonary bypass. To test this, the investigators will be taking small pieces of heart tissue from patients undergoing heart surgery before and after this period of ischemi...
What is the current status of trial NCT00985049?
This trial is currently recruiting. The enrollment target is 350 participants. The study started on 2009-03. Estimated completion is 2025-12.
What conditions does trial NCT00985049 study?
This clinical trial studies the following conditions: Cardiovascular Diseases.
Who is sponsoring clinical trial NCT00985049?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00985049 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Cardiovascular Diseases
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00985049's enrollment target sits among peer trials
350 112th of 300 higher than 188 of 300 other Cardiovascular Diseases trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Cardiovascular Diseases trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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