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ClinicalTrials.gov 41 recruiting now early-phase tilt

Suicide: early-phase trial registry

41 of 93 indexed Suicide trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #145 of 28,707 conditions by registered trial count.

93 US clinical trials · 41 currently recruiting · #145 of 28,707 conditions by registered trial count

Suicide: 93 US clinical trials tracked, 41 recruiting.

Suicide is the subject of 93 registered US clinical trials on ClinicalTrials.gov, 41 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 7 of these trials.

Enrollment posture brief

Registry condition suicide

OPEN 41 | RECR 44% | LATE 2 | EARLY 12 | RANK #145 | SPON 7

Nearest open-share peer: Cardiovascular Diseases (44% recruiting · 304 trials)

Metastatic Malignant Solid N49.5%Substance Use Disorders45.7%Suicide (this)44%Glaucoma41.5%Fallopian Tube Cancer29%
Open-enrollment share among volume-matched conditions near Suicide

Suicide lists 41 open slots (44% of 93 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Suicide on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Suicide is recruiting above its size-band peers.

    41 of 93 indexed trials (44.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Suicide trials is spread across many organizations.

    VA Office of Research and Development accounts for 7 of 93 trials (7.5%). 57 distinct sponsors appear on at least one study for this condition label.

  3. Typical Suicide enrolment sits around 103 participants.

    Median target enrolment is 103 among the 93 trials that report a genuine target (sentinel values excluded). 43 of those (46.2%) plan for fewer than 100 participants.

  4. Suicide research is mostly interventional.

    89 interventional and 4 observational studies make up this index (95.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 29Phase 32

Open and recent trials

93 total, page 1 of 2

RECRUITING NA 12,838 participants

e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide

Columbia University

NCT03586895

RECRUITING NA 4,000 participants

Reaching Out to Distressed Medical Residents, Fellows and Faculty

Oregon Health and Science University

NCT02010866

RECRUITING NA 4,000 participants

Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors

Massachusetts General Hospital

NCT05671133

RECRUITING Phase 2 1,600 participants

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

University of California, Los Angeles

NCT05304065

RECRUITING NA 1,485 participants

Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care

Elizabeth Arnold

NCT05869552

RECRUITING NA 1,000 participants

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Johns Hopkins University

NCT06151158

RECRUITING 500 participants

Natural History of Depression, Bipolar Disorder and Suicide Risk

National Institute of Mental Health (NIMH)

NCT06462196

RECRUITING Phase 2 472 participants

Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

VA Eastern Colorado Health Care System

NCT06375083

RECRUITING NA 468 participants

Mental Health in Primary Care

University of Miami

NCT05426057

RECRUITING NA 420 participants

Text-based Support for Parents of Adolescents Following an Emergency Department Visits

University of Michigan

NCT06660199

RECRUITING NA 300 participants

Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago

University of Chicago

NCT07125144

RECRUITING NA 240 participants

Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

University of Alabama at Birmingham

NCT05437588

RECRUITING NA 213 participants

Intensive Crisis Intervention

Jennifer Hughes

NCT06476886

RECRUITING NA 200 participants

Real-time Examination of Skills and Coping Use in Teen's Everyday Lives

University of Utah

NCT06720753

RECRUITING NA 185 participants

Just-in-time Interventions for Reducing Short-term Suicide Risk

Massachusetts General Hospital

NCT05793541

RECRUITING NA 180 participants

Caring Connections Youth Suicide Detection and Intervention Study

University of North Carolina, Chapel Hill

NCT06353711

RECRUITING NA 170 participants

Suicide Prevention for Sexual and Gender Minority Youth (Randomized Controlled Trial)

San Diego State University

NCT05669976

RECRUITING NA 169 participants

Risk and Resilience to Suicide Following Late-Life Spousal Bereavement

University of Pittsburgh

NCT06191484

RECRUITING 144 participants

Proximal Risk for Suicide in Adolescents

Oregon Health and Science University

NCT06400810

RECRUITING Phase 2 136 participants

Suicide Risk Interventions

VA Office of Research and Development

NCT05931289

RECRUITING NA 100 participants

Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD

Texas Tech University

NCT06055322

RECRUITING Phase 3 100 participants

Study About Group and Phone Follow-Up After a Crisis

University of Rochester

NCT05637203

RECRUITING NA 90 participants

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

University of Pittsburgh

NCT06963463

RECRUITING NA 80 participants

Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

Baylor College of Medicine

NCT05489042

RECRUITING NA 80 participants

Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics

Massachusetts General Hospital

NCT04130958

RECRUITING NA 78 participants

A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide

Ksana Health

NCT05920252

RECRUITING NA 68 participants

Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis

University of Maryland, Baltimore

NCT05440214

RECRUITING NA 60 participants

Youth Empowerment and Safety Intervention

Case Western Reserve University

NCT07214233

RECRUITING NA 60 participants

Brief Cognitive Behavioral Therapy for People With Physical Disabilities

Ohio State University

NCT05695430

RECRUITING Phase 1 57 participants

Army-SPRING Army-Suicide Prevention Research

University of Pennsylvania

NCT06547008

RECRUITING NA 57 participants

Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans

VA Office of Research and Development

NCT04731519

RECRUITING NA 50 participants

Randomized Clinical Trial of Supplementing Brief Psychotherapy With a Mobile App

Rutgers, The State University of New Jersey

NCT06555094

RECRUITING NA 50 participants

The Use of Voice-Based AI in 988 Crisis Counseling

Lyssn.io

NCT06299384

RECRUITING Phase 1 50 participants

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Lindsay Maguire, MD

NCT06085937

RECRUITING Phase 2 50 participants

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

National Institute of Mental Health (NIMH)

NCT06511908

RECRUITING NA 50 participants

Mobile Intervention for Suicidal Thoughts

VA Office of Research and Development

NCT06593379

RECRUITING NA 30 participants

NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics

West Virginia University

NCT06808503

RECRUITING NA 26 participants

Co-Designing a Virtual Reality Intervention to Enhance Skill Development

University of North Carolina, Chapel Hill

NCT07186543

RECRUITING Phase 2 24 participants

Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

The University of Texas Health Science Center at San Antonio

NCT05696691

RECRUITING NA 15 participants

Suicide Specific Rumination in Veterans

VA Office of Research and Development

NCT06481033

RECRUITING NA 10 participants

Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)

Butler Hospital

NCT05180344

ACTIVE NOT RECRUITING NA 52,323 participants

The Community Youth Development Study: A Test of Communities That Care

University of Washington

NCT01088542

ACTIVE NOT RECRUITING NA 3,629 participants

Scaling up e-Connect in Juvenile Probation Settings

New York State Psychiatric Institute

NCT05541926

ACTIVE NOT RECRUITING NA 1,491 participants

Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska

University of Michigan

NCT03661255

ACTIVE NOT RECRUITING NA 854 participants

Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial

St. Luke's Health System, Boise, Idaho

NCT06128239

ACTIVE NOT RECRUITING NA 850 participants

Veterans Coordinated Community Care (3C) Study

Brown University

NCT05272176

ACTIVE NOT RECRUITING NA 512 participants

Preventing Suicide in African American Adolescents

DePaul University

NCT04253002

ACTIVE NOT RECRUITING NA 300 participants

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

University of Michigan

NCT05282225

ACTIVE NOT RECRUITING 250 participants

Wearable Suicidal Early Warning System for Adolescents

Oregon Health and Science University

NCT03030924

ACTIVE NOT RECRUITING NA 191 participants

Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy

Ohio State University

NCT05275101

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Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 9
Phase 3 2

Named interventions

Most-linked intervention names on Suicide records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Treatment as Usual Behavioral
4 trials
Safety Planning Behavioral
2 trials
e-Connect Behavioral
2 trials
Safety Planning Intervention with Navigation Services Behavioral
2 trials
Mobile Application to Prevent Suicide (MAPS) Behavioral
2 trials
Cognitive Behavioral Therapy (CBT) Worksheets Behavioral
2 trials
Safety Planning Intervention Behavioral
2 trials
Treatment as usual Behavioral
2 trials

US sites by state

Facility locations filed on Suicide trials. A trial with sites in several states counts in each.

Pennsylvania 9 trials
Massachusetts 8 trials
Rhode Island 7 trials
New York 7 trials
Washington 6 trials
Texas 6 trials
Ohio 6 trials
North Carolina 6 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Suicide page

93 registered trials, 41 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Suicide condition card totals 93 registered trials; most-linked intervention Treatment as Usual; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.