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Suicide
Open-data reference.
93 US clinical trials · 41 currently recruiting
Active & Recent Trials
e-Connect: A Service System Intervention for Justice Youth at Risk for Suicide
Columbia University
NCT03586895
Reaching Out to Distressed Medical Residents, Fellows and Faculty
Oregon Health and Science University
NCT02010866
Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors
Massachusetts General Hospital
NCT05671133
Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth
University of California, Los Angeles
NCT05304065
Preventing Suicide Among Sexual and Gender Diverse Young Adults in Primary Care
Elizabeth Arnold
NCT05869552
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
Johns Hopkins University
NCT06151158
Natural History of Depression, Bipolar Disorder and Suicide Risk
National Institute of Mental Health (NIMH)
NCT06462196
Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression
VA Eastern Colorado Health Care System
NCT06375083
Mental Health in Primary Care
University of Miami
NCT05426057
Text-based Support for Parents of Adolescents Following an Emergency Department Visits
University of Michigan
NCT06660199
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
University of Chicago
NCT07125144
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
University of Alabama at Birmingham
NCT05437588
Intensive Crisis Intervention
Jennifer Hughes
NCT06476886
Real-time Examination of Skills and Coping Use in Teen's Everyday Lives
University of Utah
NCT06720753
Just-in-time Interventions for Reducing Short-term Suicide Risk
Massachusetts General Hospital
NCT05793541
Caring Connections Youth Suicide Detection and Intervention Study
University of North Carolina, Chapel Hill
NCT06353711
Suicide Prevention for Sexual and Gender Minority Youth (Randomized Controlled Trial)
San Diego State University
NCT05669976
Risk and Resilience to Suicide Following Late-Life Spousal Bereavement
University of Pittsburgh
NCT06191484
Proximal Risk for Suicide in Adolescents
Oregon Health and Science University
NCT06400810
Suicide Risk Interventions
VA Office of Research and Development
NCT05931289
Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD
Texas Tech University
NCT06055322
Study About Group and Phone Follow-Up After a Crisis
University of Rochester
NCT05637203
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
University of Pittsburgh
NCT06963463
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Baylor College of Medicine
NCT05489042
Circuit-Based Approach to Suicide: Biomarkers, Predictors, and Novel Therapeutics
Massachusetts General Hospital
NCT04130958
A Digitally Assisted Risk Reduction Platform for Youth at High Risk for Suicide
Ksana Health
NCT05920252
Targeting Emotion Dysregulation to Reduce Suicide in People With Psychosis
University of Maryland, Baltimore
NCT05440214
Youth Empowerment and Safety Intervention
Case Western Reserve University
NCT07214233
Brief Cognitive Behavioral Therapy for People With Physical Disabilities
Ohio State University
NCT05695430
Army-SPRING Army-Suicide Prevention Research
University of Pennsylvania
NCT06547008
Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans
VA Office of Research and Development
NCT04731519
Randomized Clinical Trial of Supplementing Brief Psychotherapy With a Mobile App
Rutgers, The State University of New Jersey
NCT06555094
The Use of Voice-Based AI in 988 Crisis Counseling
Lyssn.io
NCT06299384
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
Lindsay Maguire, MD
NCT06085937
Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression
National Institute of Mental Health (NIMH)
NCT06511908
Mobile Intervention for Suicidal Thoughts
VA Office of Research and Development
NCT06593379
NIMH Clinical Pathway in Rural Appalachian School-based Health Clinics
West Virginia University
NCT06808503
Co-Designing a Virtual Reality Intervention to Enhance Skill Development
University of North Carolina, Chapel Hill
NCT07186543
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
The University of Texas Health Science Center at San Antonio
NCT05696691
Suicide Specific Rumination in Veterans
VA Office of Research and Development
NCT06481033
Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial (2)
Butler Hospital
NCT05180344
The Community Youth Development Study: A Test of Communities That Care
University of Washington
NCT01088542
Scaling up e-Connect in Juvenile Probation Settings
New York State Psychiatric Institute
NCT05541926
Promoting Community Conversations About Research to End Native Youth Suicide in Rural Alaska
University of Michigan
NCT03661255
Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial
St. Luke's Health System, Boise, Idaho
NCT06128239
Veterans Coordinated Community Care (3C) Study
Brown University
NCT05272176
Preventing Suicide in African American Adolescents
DePaul University
NCT04253002
Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care
University of Michigan
NCT05282225
Wearable Suicidal Early Warning System for Adolescents
Oregon Health and Science University
NCT03030924
Neural Mechanisms and Predictors of an Ultra-Brief Suicide Prevention Strategy
Ohio State University
NCT05275101
Treatment for Relationships and Safety Together
VA Office of Research and Development
NCT04816149
Family Safety Net - Aim 3: Randomized Control Trial
University of Michigan
NCT05657119
Youth Nominated Support Team
University of California, Irvine
NCT05558332
Optimizing a Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents
Ksana Health
NCT06665620
A System of Safety (SOS)
University of Massachusetts, Worcester
NCT03104504
Evaluation of a School-Based Training Program for Suicide Prevention
University of Rochester
NCT00118443
Peer to Peer Programs for Military Suicide Prevention
University of Utah
NCT04021758
Systems Aligning for Equity (SAFE) Spaces
New York University
NCT05658068
Social Ecology and the Prevention of Suicide and Aggression in African American Youth
DePaul University
NCT03954457
Preventing Addiction Related Suicide (PARS)
University of Washington
NCT03166709
Suicide Prevention Intervention for At-Risk Individuals in Transition
Michigan State University
NCT02759172
Facilitating Use of the National Suicide Prevention Lifeline in Alcohol Patients (Reach Out)
University of Michigan
NCT04488055
Improving Firearm Storage in Alaska Native Villages
University of Washington
NCT00643812
Building Stronger Allies
Florida State University
NCT03571750
Now Matters Now: An Online Suicide Prevention Program
Kaiser Permanente
NCT01924936
Family-based Crisis Intervention With Suicidal Adolescents in the ED
Boston Children's Hospital
NCT02610309
Mindfulness-Based Cognitive Therapy for Suicide Prevention
VA Office of Research and Development
NCT01872338
Wakȟáŋyeža (Little Holy One)
Johns Hopkins University
NCT04201184
TMS for Suicidal Crisis in Active Duty SMs
Eisenhower Army Medical Center
NCT03014362
Suicide Prediction and Prevention for People at Risk for Opioid Use Disorder: Supplement to COMPUTE 2.0
HealthPartners Institute
NCT04939727
Promoting Safety Plan and Coping Strategy Use Among Adults With Suicidal Thoughts
Massachusetts General Hospital
NCT05791643
A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT01360736
Treatment of Suicidal Women With Borderline Personality Disorder
University of Washington
NCT00183651
Biomarkers as Predictors of Suicidal Risk in Adolescents
The Cleveland Clinic
NCT03014518
Computerized Anxiety Treatment for Suicide
Florida State University
NCT01990131
Effectiveness of a Family-Based Intervention for Adolescent Suicide Attempters (The SAFETY Study)
University of California, Los Angeles
NCT00692302
Preventing Youth Suicide in Primary Care: A Family Model
Children's Hospital of Philadelphia
NCT00604097
Reducing Suicide Risk in Adolescents and Young Adults Via a Psychobehavioral Intervention to Regularize Daily Rhythms
Yale University
NCT05317481
Suicide Prevention Intervention for Vulnerable Emerging Adult Sexual Minorities
University of Pennsylvania
NCT05018143
Developing an Intervention to Promote Lethal Means Safety in Suicidal Adolescents
University of Texas Southwestern Medical Center
NCT05423483
Suicide Prevention for Patients With Chronic Pain
Veterans BioMedical Research Institute
NCT04490265
Practice Experiences for School Reintegration
University of North Carolina, Chapel Hill
NCT05934396
Assisting in Decisions in Emergency Departments: (ED-AID) Study
University of Colorado, Denver
NCT03478501
Latino/a Adolescents With Suicidal Behavior
Brown University
NCT02820636
Pilot RCT of a Video-based Intervention for Suicide Prevention
Butler Hospital
NCT05127330
Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)
San Diego State University
NCT05087966
Pilot of Training on 988 and Narcan
RAND
NCT07072819
CAMS-RAS: for Suicide Prevention
Evidence-Based Practice Institute, Seattle, WA
NCT03072875
Concurrent Treatment for Depressed Parents and DepressedAdolescents
Brown University
NCT00951821
Efficacy of a Brief Nightmare Treatment for Veterans
University of Tul
NCT01220401
Effects of Neuromodulation and Cognitive Training for Suicide in Veterans (ENACTS)
VA Office of Research and Development
NCT05231213
Ketamine for Depression and Suicide Risk
Mayo Clinic
NCT02094898
Feasibility, Acceptability, and Preliminary Efficacy of a Novel Personalized Mobile Intervention for Suicide - Open Trial
Butler Hospital
NCT05180331
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 3 |
| Phase 2 | 9 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Suicide Trial Landscape
ClinicalTrials.gov lists 93 US studies indexed under Suicide, and 41 of those are currently open to recruitment — roughly 44% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Suicide shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Suicide is led by VA Office of Research and Development with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 93 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Suicide?
PlainTrial tracks 93 US clinical trials for Suicide, of which 41 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Suicide?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.