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Cardiovascular Diseases clinical trials
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
304 US clinical trials · 134 currently recruiting
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
The research picture
Cardiovascular Diseases has 304 registered US clinical trials, 134 of them open to new participants right now, about 44% of the total.
- 134
- recruiting participants now
- 44%
- of trials open to enrollment
- 26
- in Phase 3–4 (later-stage)
- 10
- top sponsor: Duke University
Active & Recent Trials
304 total, page 1 of 7
Observational Pharmaco-Epidemiology Research & Analysis
Epividian
NCT03813862
A Study of Mayo Clinic CV Research Heart & Voice Study
Mayo Clinic
NCT07224685
The Oxford Risk Factors And Non-Invasive Imaging Study
University of Oxford
NCT05169333
DeBakey Cardiovascular Magnetic Resonance Study
Dipan Shah
NCT04281823
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
Duke University
NCT04262206
Food and Microbiome Longitudinal Investigation (FAMiLI)
NYU Langone Health
NCT03293758
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Boehringer Ingelheim
NCT07064473
Cardiovascular and Metabolic Sciences Biorepository
The Cleveland Clinic
NCT06560424
Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility
Brooklyn Clinical Research
NCT06412536
Cardiovascular Health Improvement Project
University of Michigan
NCT02306200
CVD/PH and Voice Characteristics
Mayo Clinic
NCT07311044
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health.
Clindove Research
NCT07106879
Global Cardio Oncology Registry
The Cleveland Clinic
NCT05598879
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"
NHS Greater Glasgow and Clyde
NCT05919342
Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates
University of British Columbia
NCT03674307
Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
University of Colorado, Denver
NCT06324981
Phase I Human Analytics (HALO) Study
HALO Diagnostics
NCT05423860
Diabetes and Heart Disease Risk in Blacks
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001853
Aging, Geriatric Syndromes and Clonal Hematopoiesis
Washington University School of Medicine
NCT02604563
MagicTouch™Sirolimus-Coated Balloon for Treatment of Coronary Artery Lesions in Small Vessels
Concept Medical
NCT06271590
Longitudinal Real-world Clinical Outcomes Study on Symplicity Renal Denervation
Medtronic Vascular
NCT07174622
Community Park-Based Programs for Health Promotion: Active Older Adults Prospective Cohort Study
Duke University
NCT06604650
Mayo AVC Registry and Biobank
Mayo Clinic
NCT03049254
The RADIANCE CED Study
ReCor Medical
NCT07231757
Pivotal Study for the Cardiac Performance System (CPS)
Sensydia Corporation
NCT06870591
Thrombosis and Inflammation in Vessels Initiative (TIVI)
National Heart, Lung, and Blood Institute (NHLBI)
NCT06552767
Global Paradise System US Post Approval Study
ReCor Medical
NCT06297291
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
AliveCor
NCT06271577
Development of CIRC Technologies
The Cleveland Clinic
NCT05654272
GC-PRO Intervention
University of Minnesota
NCT06671704
Healthy School Recognized Campus: A Hybrid Type 2 Implementation-Effectiveness Trial
Texas A&M University
NCT07079995
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Abbott Medical Devices
NCT06526195
Health, Environment and Action in Louisville (HEAL) Green Heart Louisville Project
University of Louisville
NCT03670524
Church-based Health Intervention to Eliminate Racial Inequalities in Cardiovascular Health
Tulane University
NCT06065098
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
BrioHealth Solutions
NCT06310031
Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients
Ohio State University
NCT06586970
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
Fundación EPIC
NCT07286578
Military Health and Nutrition Examination Study
Pennington Biomedical Research Center
NCT06380322
Enhancing Capacity in Churches to Implement PA Programs
San Diego State University
NCT05473871
Prevention of Cardiovascular Disease and Mortality in Patients With Psoriasis or Psoriatic Arthritis
University of Pennsylvania
NCT05908240
American Indian Chronic Renal Insufficiency Cohort Study (AI-CRIC Study)
University of New Mexi
NCT04185844
Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
University of South Carolina
NCT05370014
Biobank Cardiac Surgery
University of Chicago
NCT06747806
Strong Teens for Healthy Schools Change Club: A Civic Engagement Approach to Improving Physical Activity and Healthy Eating Environments
Texas A&M University
NCT05867433
Philly CEAL- DECIDE+ Adaptation
University of Pennsylvania
NCT06732102
Vascular Lab Resource (VLR) Biorepository
The Cleveland Clinic
NCT05628948
CARBON: UAB Cardiovascular Research Biobank
University of Alabama at Birmingham
NCT05067231
MagicTouch for Treatment of In-Stent Restenosis in Coronary Artery Lesions
Concept Medical
NCT05908331
Multi-Center Study of Clinical and Inflammatory Outcomes in Intensive Cardiac Rehabilitation and Traditional Cardiac Rehabilitation Programs
Pritikin ICR
NCT06424119
Cerebrovascular Health and Resilience in Midlife
University of Pittsburgh
NCT06029348
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cardiovascular Diseases Trial Landscape
304 indexed Cardiovascular Diseases studies · 134 recruiting (44%).
Phase mix: 26 late (III/IV) vs 28 early (I/II).
Top sponsor: Duke University (10 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cardiovascular Diseases?
PlainTrial tracks 304 US clinical trials for Cardiovascular Diseases, of which 134 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cardiovascular Diseases?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.