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SPYRAL GEMINI Pilot Study
NCT06907147 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.
Conditions Studied
Interventions
- DEVICE Multi-Organ Denervation Gemini System
Study Locations (13)
Other
- Royal Perth Hospital (Dobney Hypertension Centre) — Perth
- Hippokration General Hospital — Athens
- University Hospital of Galway — Galway
- University Hospital Basel — Basel
Texas
- Baylor Heart & Vascular Hospital — Dallas
- UT Health East Texas — Tyler
California
- Stanford Hospital and Clinics — Stanford
Georgia
- Piedmont Heart Institute — Atlanta
Massachusetts
- Beth Israel Deaconess Medical Center — Boston
Michigan
- Henry Ford Providence Hospital — Southfield
Mississippi
- North Mississippi Medical Center — Tupelo
Nevada
- Renown Regional Medical Center — Reno
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 175 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2029-12-22 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06907147
The ClinicalTrials.gov registry entry for NCT06907147 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 175 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medtronic Vascular, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 5 conditions, with Hypertension appearing as the primary indexed condition, and to 1 intervention — of which Multi-Organ Denervation Gemini System is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06907147 reports 13 study locations spanning 9 distinct geographic areas — top geographies include Other, Texas, California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06907147 about?
NCT06907147 is a clinical study titled "SPYRAL GEMINI Pilot Study". The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.
What is the current status of trial NCT06907147?
This trial is currently recruiting. It is a NA study. The enrollment target is 175 participants. The study started on 2025-05-01. Estimated completion is 2029-12-22.
What conditions does trial NCT06907147 study?
This clinical trial studies the following conditions: Hypertension, Cardiovascular Diseases, Diabetes Mellitus, Chronic Kidney Diseases, Vascular Diseases. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06907147?
The interventions under investigation include: Multi-Organ Denervation Gemini System (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06907147?
This trial is sponsored by Medtronic Vascular, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06907147 being conducted?
This trial has 13 study locations across California, Georgia, Massachusetts, Michigan, Mississippi. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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