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Cardiovascular Diseases: full-pipeline trial registry
134 of 304 indexed Cardiovascular Diseases trials are currently recruiting.
Corpus placement: #27 of 28,707 conditions by registered trial count.
304 US clinical trials · 134 currently recruiting · #27 of 28,707 conditions by registered trial count
Cardiovascular Diseases: 304 US clinical trials tracked, 134 recruiting.
Cardiovascular Diseases is the subject of 304 registered US clinical trials on ClinicalTrials.gov, 134 of them currently open to new participants. 26 are in Phase 3-4 (later-stage) and 28 in Phase 1-2 (earlier-stage). The most active sponsor is Duke University, running 10 of these trials.
Enrollment posture brief
Registry condition cardiovascular-diseases
OPEN 134 | RECR 44% | LATE 26 | EARLY 28 | RANK #27 | SPON 10
Volume-matched condition peers
Nearest open-share peer: Suicide (44% recruiting · 93 trials)
Cardiovascular Diseases lists 134 open slots (44% of 304 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Cardiovascular Diseases on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Cardiovascular Diseases is recruiting above its size-band peers.
134 of 304 indexed trials (44.1%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Cardiovascular Diseases trials is spread across many organizations.
Duke University accounts for 10 of 304 trials (3.3%). 159 distinct sponsors appear on at least one study for this condition label.
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Typical Cardiovascular Diseases enrolment sits around 200 participants.
Median target enrolment is 200 among the 301 trials that report a genuine target (sentinel values excluded). 101 of those (33.6%) plan for fewer than 100 participants.
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Cardiovascular Diseases research is mostly interventional.
225 interventional and 79 observational studies make up this index (74% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
304 total, page 3 of 7
MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes
Kalie Tommerdahl
NCT05065372
Role of Endothelial Function in SCI CVD Risk
Craig Hospital
NCT06443151
Treatment With Aspirin After Preeclampsia: TAP Trial
Malamo Countouris
NCT06281665
Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics
Washington University School of Medicine
NCT06063564
Role of Adiposomes in Endothelial Dysfunction
University of Illinois at Chicago
NCT05199454
Designing and Assessing a Women Only Cardiac Rehabilitation (CARE) Program
University of Michigan
NCT06784895
HIIT Effects on Cardiometabolic Health
Syracuse University
NCT05838950
The Weight of Cardiovascular Disease
Mayo Clinic
NCT06053645
ADAPT Micro-Randomized Trial
University of Michigan
NCT06915220
The Effects of Healthy Diets With Plant Oils on Heart and Metabolic Health
Penn State University
NCT06216678
Personalized GI Motility Responses to Diet
University of Illinois at Urbana-Champaign
NCT06386471
Imaging of Retinochoroidal Vasculature in Patients Being Assessed for Cardiovascular Disease
Northwestern University
NCT05082402
Mindfulness and Behavior Change to Improve Cardiovascular Health of Older People With HIV
Massachusetts General Hospital
NCT06001814
Identifying Strategies to Reduce Cardiovascular Risk Among Mothers of Young Children
NYU Langone Health
NCT06796075
Ketogenic Diet in Healthy Adults With Differing BMI
Penn State University
NCT06515912
PKP2-ACM Natural History Study
Rocket Pharmaceuticals
NCT06644742
Sleep and Circadian Mechanisms in Hypertension
Oregon Health and Science University
NCT05184933
Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy
University of Utah
NCT05826925
NSAIDs vs. Coxibs in the Presence of Aspirin
Inova Health Care Services
NCT03699293
A Pilot Feasibility and Acceptability Study of Remote ExerciSe Training mOdalities (PRESTO)
NYU Langone Health
NCT06931470
Remote Vinyasa Yoga Program for Heart Health
West Virginia University
NCT06961981
WatchWell: Simple and Practical Strategies to Reduce the Negative Health Impact of Sedentary Screen Time
Arizona State University
NCT06963736
Role of Aging and Individual Variation in Exercise Training Responsiveness
Duke University
NCT06471569
Evaluating Infrasonic Hemodynography
Scripps Health
NCT04636892
Two-Year Study of the Safety and Efficacy of the Second-Generation Tissue Engineered Vascular Grafts
Nationwide Children's Hospital
NCT04467671
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
University of Kansas Medical Center
NCT04715022
A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
Pulmovant
NCT07333183
Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN )
Wake Forest University
NCT06375694
The TRICURE EFS Study
TRiCares
NCT06506942
Spinal Cord Transcutaneous Stimulation Effect on Blood Pressure in Acute Spinal Cord Injury (SCI)
Kessler Foundation
NCT05731986
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
Jorge Gonzalez-Martinez
NCT06303869
The Influence of Chardonnay Marc Intake on Gut and Cardiometabolic Health
University of California, Davis
NCT06476795
The Effect of Transcutaneous Stimulation on Blood Pressure in Spinal Cord Injury (SCI)
Kessler Foundation
NCT05725499
Chardonnay Marc and Vascular Response
University of California, Davis
NCT05545865
Kaiser Permanente VACCination Improvement With Nudge-based CardiovAscular Targeted Engagement
Kaiser Permanente
NCT06571747
Bogalusa Heart Study
Tulane University
NCT00005129
University of North Carolina Alumni Heart Study
Duke University
NCT00005398
Cardiovascular Health Study (CHS)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005133
The Jackson Heart Study of Cardiovascular Disease Among African Americans
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005485
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
Eli Lilly and Company
NCT05803421
Repository of Phase Signals for Pulmonary Hypertension Algorithm Development
Analytics For Life
NCT04031989
Mediators of Atherosclerosis in South Asians Living in America
University of California, San Francisco
NCT01207167
Novel Strategies for Reducing Heart Disease Risk Disparities
University of Pittsburgh
NCT00143923
A Study of Retatrutide (LY3437943) in Participants With Obesity and Cardiovascular Disease
Eli Lilly and Company
NCT05882045
CardioSeq: Impact of WGS in Individuals With CVD
Illumina
NCT05656183
SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
Medtronic Vascular
NCT05198674
Developing a Learning COmmunity to Increase eNgagemeNt and Enrollment in Cardiovascular Clinical Trials (CONNECT)
Johns Hopkins University
NCT06347484
TRISCEND II Pivotal Trial
Edwards Lifesciences
NCT04482062
A Tool to Help Patients With Muscle Symptoms After Taking a Statin Medication.
University of Utah
NCT06423365
Impact of Patient-Centered Approach for Communicating Coronary Calcium on Cardiovascular Health
American College of Radiology
NCT06055972
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 18 |
| Phase 3 | 13 |
| Phase 4 | 13 |
Top Sponsors
Named interventions
Most-linked intervention names on Cardiovascular Diseases records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Cardiovascular Diseases trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Cardiovascular Diseases page
304 registered trials, 134 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 134 Cardiovascular Diseases trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Duke University sponsors the most Cardiovascular Diseases trials on record, review their full trial history before evaluating a specific study. See Duke University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiovascular Diseases condition card totals 304 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.