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NCT02505529 · ClinicalTrials.gov registry record · NA

The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders

A NA study of Aging, sponsored by Ohio University.

Completed
Registry status
NA
Development phase
89
Enrollment target
1
Study location

NCT02505529 is a NA study of Aging that has completed, run by Ohio University. The registered enrollment target is 89 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02505529, a NA study of Aging, has completed, sponsored by Ohio University.

COMPLETED
Registry status
NA
Development phase
89 participants
Enrollment target
1
Study location

Study Summary

The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical and cognitive function as well as a battery of tests to 1) quantify brain excitability (using non-invasive transcranial magnetic stimulation), 2) modulate brain excitability (using non-invasive transcranial direct current stimulation), 3) spinal motor nerve firing characteristics, and 4) brain structure and function characteristics based on magnetic resonance images of the brain. Additionally, three option sub-studies are also available for enrollment. The first is a genetics sub-study where a cheek swab will be used to examine associations between certain genes and the physiological and functional measures obtained from the main study. The other two sub-studies are interventions. The first sub-study is a progressive resistance exercise training study where study participants will undergo 12-weeks of exercise training (3x/wk) and at the completion of the exercise training the measures obtained in the main study will be re-assessed. The other sub-study is a mental imagery sub-study where subjects are randomly assigned to perform a mental imagery training program consisting of imaging strong muscle contractions and mobility tasks (5x/wk) or to serve as a control (i.e., to not modify lifestyle) for 6-weeks. At the completion of the respective intervention period the measures obtained in the main study will be re-assessed.

Conditions Studied

Aging

Interventions

  • OTHER Mental Imagery
  • OTHER Resistance Exercise Training

Study Locations (1)

Ohio

  • Ohio Musculoskeletal and Neurological Institute (OMNI) at Ohio University - Athens

Trial Details

FieldValue
Enrollment Target 89 participants
Start Date 2015-07
Est. Completion 2018-12
Phase NA

Sponsor

Ohio University

51 total trials

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What the Registry Record Tells You About NCT02505529

The ClinicalTrials.gov registry entry for NCT02505529 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 89 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (96% lower). The listed sponsor is Ohio University, which has 51 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Mental Imagery is the first listed.

NCT02505529 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT02505529 about?

NCT02505529 is a clinical study titled "The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders". The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical and cognitive function as well as a battery of tests to 1) quantify bra...

What is the current status of trial NCT02505529?

This trial is currently completed. It is a NA study. The enrollment target is 89 participants. The study started on 2015-07. Estimated completion is 2018-12.

What conditions does trial NCT02505529 study?

This clinical trial studies the following conditions: Aging.

What interventions are being tested in trial NCT02505529?

The interventions under investigation include: Mental Imagery (OTHER), Resistance Exercise Training (OTHER).

Who is sponsoring clinical trial NCT02505529?

This trial is sponsored by Ohio University, which has 51 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02505529 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.