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NCT02505529 · ClinicalTrials.gov registry record · NA
The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders
A NA study of Aging, sponsored by Ohio University.
- Completed
- Registry status
- NA
- Development phase
- 89
- Enrollment target
- 1
- Study location
NCT02505529: Completed NA study of Aging, sponsored by Ohio University.
NCT02505529 is a NA study of Aging that has completed, run by Ohio University. The registered enrollment target is 89 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02505529, a NA study of Aging, has completed, sponsored by Ohio University.
- COMPLETED
- Registry status
- NA
- Development phase
- 89 participants
- Enrollment target
- 1
- Study location
Study Summary
The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical and cognitive function as well as a battery of tests to 1) quantify brain excitability (using non-invasive transcranial magnetic stimulation), 2) modulate brain excitability (using non-invasive transcranial direct current stimulation), 3) spinal motor nerve firing characteristics, and 4) brain structure and function characteristics based on magnetic resonance images of the brain. Additionally, three option sub-studies are also available for enrollment. The first is a genetics sub-study where a cheek swab will be used to examine associations between certain genes and the physiological and functional measures obtained from the main study. The other two sub-studies are interventions. The first sub-study is a progressive resistance exercise training study where study participants will undergo 12-weeks of exercise training (3x/wk) and at the completion of the exercise training the measures obtained in the main study will be re-assessed. The other sub-study is a mental imagery sub-study where subjects are randomly assigned to perform a mental imagery training program consisting of imaging strong muscle contractions and mobility tasks (5x/wk) or to serve as a control (i.e., to not modify lifestyle) for 6-weeks. At the completion of the respective intervention period the measures obtained in the main study will be re-assessed.
Primary Outcome
Obtained using transcranial magnetic stimulation
Conditions Studied
Interventions
- OTHER Mental Imagery
- OTHER Resistance Exercise Training
Study Locations (1)
Ohio
- Ohio Musculoskeletal and Neurological Institute (OMNI) at Ohio University - Athens
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 89 participants |
| Start Date | 2015-07 |
| Est. Completion | 2018-12 |
| Phase | NA |
What the finished NCT02505529 record still lists
NCT02505529 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 89 participants, a relatively small participant target, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Mental Imagery is the first listed.
NCT02505529 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT02505529 about?
NCT02505529 is a clinical study titled "The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders". The UNCODE Study seeks to better identify the neurological causes of muscle weakness associated with advancing age. The main study consists of 4 laboratory-based testing sessions that involve testing muscle strength and physical and cognitive function as well as a battery of tests to 1) quantify bra...
What is the current status of trial NCT02505529?
This trial is currently completed. It is a NA study. The enrollment target is 89 participants. The study started on 2015-07. Estimated completion is 2018-12.
What conditions does trial NCT02505529 study?
This clinical trial studies the following conditions: Aging.
What interventions are being tested in trial NCT02505529?
The interventions under investigation include: Mental Imagery (OTHER), Resistance Exercise Training (OTHER).
Who is sponsoring clinical trial NCT02505529?
This trial is sponsored by Ohio University, which has 51 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02505529 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02505529's enrollment target sits among peer trials
89 105th of 262 higher than 158 of 262 other Aging trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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