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NCT07475546 · ClinicalTrials.gov registry record · Phase 3

Combination Gerotherapeutic Interventions for Healthspan Improvement

A Phase 3 study of Aging and Longevity, sponsored by AgelessRx.

Active
Registry status
Phase 3
Development phase
30
Enrollment target
1
Study location

NCT07475546 is a Phase 3 study of Aging and Longevity that is active but no longer recruiting, run by AgelessRx. The registered enrollment target is 30 participants, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07475546, a Phase 3 study of Aging and Longevity, is active but no longer recruiting, sponsored by AgelessRx.

ACTIVE NOT RECRUITING
Registry status
Phase 3
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This study is a 90-day interventional, randomized, controlled pilot trial exploring multi-modal gerotherapies and their impact on longevity-related outcomes. In this proof-of-concept phase, a small sample size of up to 30 subjects (10 subjects in each arm) will be randomized into one of the three arms: 1) Control, 2) Multi-therapy (B12, Naltrexone, Metformin, and NAD+), or 4) Comprehensive Therapy (Rapamycin, Naltrexone, Metformin, B12, NAD+, GSH, and Infinite Supplement).

Conditions Studied

Aging Longevity Healthspan Improvement

Interventions

  • DRUG Metformin
  • DRUG Rapamycin
  • DRUG Naltrexone
  • DRUG NAD+
  • DRUG GSH

Study Locations (1)

Michigan

  • AgelessRx - Ann Arbor

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-07-23
Est. Completion 2026-04
Phase Phase 3

Sponsor

AgelessRx

7 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07475546

The ClinicalTrials.gov registry entry for NCT07475546 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,195-participant average among 262 other Aging trials with a reported enrollment target (99% lower). The listed sponsor is AgelessRx, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 5 interventions - of which Metformin is the first listed.

NCT07475546 reports 1 study location spanning 1 distinct geographic area - top geographies include Michigan.

Frequently Asked Questions

What is clinical trial NCT07475546 about?

NCT07475546 is a clinical study titled "Combination Gerotherapeutic Interventions for Healthspan Improvement". This study is a 90-day interventional, randomized, controlled pilot trial exploring multi-modal gerotherapies and their impact on longevity-related outcomes. In this proof-of-concept phase, a small sample size of up to 30 subjects (10 subjects in each arm) will be randomized into one of the three ar...

What is the current status of trial NCT07475546?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 30 participants. The study started on 2025-07-23. Estimated completion is 2026-04.

What conditions does trial NCT07475546 study?

This clinical trial studies the following conditions: Aging, Longevity, Healthspan Improvement.

What interventions are being tested in trial NCT07475546?

The interventions under investigation include: Metformin (DRUG), Rapamycin (DRUG), Naltrexone (DRUG), NAD+ (DRUG), GSH (DRUG).

Who is sponsoring clinical trial NCT07475546?

This trial is sponsored by AgelessRx, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07475546 being conducted?

This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.