Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03283462 · ClinicalTrials.gov registry record · NA

Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)

A NA study of Aging and Muscle Function, sponsored by Amazentis.

Completed
Registry status
NA
Development phase
66
Enrollment target
1
Study location

NCT03283462: Completed NA study of Aging and Muscle Function, sponsored by Amazentis.

NCT03283462 is a NA study of Aging and Muscle Function that has completed, run by Amazentis. The registered enrollment target is 66 participants, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03283462, a NA study of Aging and Muscle Function, has completed, sponsored by Amazentis.

COMPLETED
Registry status
NA
Development phase
66 participants
Enrollment target
1
Study location

Study Summary

This is a randomized, double-blind, single-center, placebo-controlled Phase 2 trial enrolling 66 healthy elderly subjects (33 placebo and 33 AMAZ-02 administration) who are ≥65 and ≤ 90 years of age with evidence of low mitochondrial function. AMAZ-02 or placebo will be orally administered for 4 months.

Interventions

  • DIETARY_SUPPLEMENT Placebo
  • DIETARY_SUPPLEMENT Mitopure

Study Locations (1)

Washington

  • University of Washington Medical Center - Seattle

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2018-02-15
Est. Completion 2020-10-28
Phase NA
Amazentis

5 total trials

What the finished NCT03283462 record still lists

NCT03283462 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 2,194-participant average among 262 other Aging trials with a reported enrollment target (97% lower).

The record links to 3 conditions, with Aging appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03283462 reports a single indexed study location in Washington.

Frequently Asked Questions

What is clinical trial NCT03283462 about?

NCT03283462 is a clinical study titled "Bioenergetics and Muscle Function Improvement With AMAZ-02 in Elderly Skeletal Muscle (ENERGIZE Trial)". This is a randomized, double-blind, single-center, placebo-controlled Phase 2 trial enrolling 66 healthy elderly subjects (33 placebo and 33 AMAZ-02 administration) who are ≥65 and ≤ 90 years of age with evidence of low mitochondrial function. AMAZ-02 or placebo will be orally administered for 4 mon...

What is the current status of trial NCT03283462?

This trial is currently completed. It is a NA study. The enrollment target is 66 participants. The study started on 2018-02-15. Estimated completion is 2020-10-28.

What conditions does trial NCT03283462 study?

This clinical trial studies the following conditions: Aging, Muscle Function, Mitochondrial Function, Bioenergetics.

What interventions are being tested in trial NCT03283462?

The interventions under investigation include: Placebo (DIETARY_SUPPLEMENT), Mitopure (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT03283462?

This trial is sponsored by Amazentis, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03283462 being conducted?

This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Aging

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03283462's enrollment target sits among peer trials

66 130th of 262 higher than 131 of 262 other Aging trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Aging trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02584244 · 66 participants · Phase 1

    Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers

  • NCT03067051 · 66 participants · Phase 1

    Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System

  • NCT03754725 · 66 participants · Phase 1

    Ferritin and Iron Burden in SAH sIRB

  • NCT03875378 · 66 participants · Phase 2

    Transdermal Estrogen in Women With Anorexia Nervosa

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03283462, the US trial registry maintained by the National Library of Medicine. NCT03283462 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.