Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Aging: early-phase trial registry
126 of 263 indexed Aging trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #38 of 28,707 conditions by registered trial count.
263 US clinical trials · 126 currently recruiting · #38 of 28,707 conditions by registered trial count
Aging: 263 US clinical trials tracked, 126 recruiting.
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
Enrollment posture brief
Registry condition aging
OPEN 126 | RECR 48% | LATE 14 | EARLY 48 | RANK #38 | SPON 14
Volume-matched condition peers
Nearest open-share peer: Lung Non-Small Cell Carcinoma (48% recruiting · 48 trials)
Aging lists 126 open slots (48% of 263 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Aging on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Aging is recruiting above its size-band peers.
126 of 263 indexed trials (47.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Aging trials is spread across many organizations.
University of Florida accounts for 14 of 263 trials (5.3%). 132 distinct sponsors appear on at least one study for this condition label.
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Most Aging trials plan to enrol fewer than 100 people.
Median target enrolment is 66 among the 263 trials that report a genuine target (sentinel values excluded). 166 of those (63.1%) plan for fewer than 100 participants.
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Aging research is mostly interventional.
228 interventional and 35 observational studies make up this index (86.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
263 total, page 5 of 6
Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults
Baylor University
NCT04785963
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age
Gladwin, Mark, MD
NCT04405180
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults
Hebrew SeniorLife
NCT03191812
The Effect of Long Duration Exercise on the Diastolic Function of the Heart
University of Texas Southwestern Medical Center
NCT02039154
Mindfulness Training in Healthy Older Veterans
VA Office of Research and Development
NCT02816723
Variability of Physical Assessments in an Older Population That is Overweight or Obese
Versanis Bio
NCT05174923
Effect of Resvida, a Comparison With Calorie Restriction Regimen
Washington University School of Medicine
NCT00823381
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
National Institute on Aging (NIA)
NCT00099697
Program for African American Cognition & Exercise
Pennington Biomedical Research Center
NCT03474302
E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons
Klein Buendel
NCT05017129
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
University of Southern California
NCT00605072
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
Big Bold Health, PBC
NCT05234203
Cognitive Behavior Therapy (CBT)-Based Group Intervention to Reduce Inflammation in Older People With HIV
Massachusetts General Hospital
NCT05434741
Breathing Room Intervention to Achieve Better Lung Health in Older Adults
University of Wisconsin, Milwaukee
NCT05330780
Emotion Study/Substudy: Flexible Brain Study
University of Florida
NCT03872414
The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
South Dakota State University
NCT04127240
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise
Northern Arizona University
NCT03419988
NanoSilk Cosmo: Evaluation of a Novel Silk Complex on Biophysical Parameters Related to Skin Aging
University of Colorado, Denver
NCT04630418
The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults
University of Delaware
NCT05211726
CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
National Institute on Aging (NIA)
NCT00099099
Cognitive Effects of Transcranial Direct Current Stimulation in Older Adults
Johns Hopkins University
NCT01611103
Role of Centrum® Silver® in Improving Micronutrient Status in Older Men
Oregon State University
NCT03004807
The Influence of Regular Beef Consumption and Protein Density of the Diet on Training-induced Gains in Muscle Strength and Performance in Healthy Adults
University of Illinois at Urbana-Champaign
NCT03029975
Evaluation of Efficacy, Tolerability, and Pharmacokinetics of MYMD1 for Chronic Inflammation and Sarcopenia/Frailty
TNF Pharmaceuticals
NCT05283486
Daily Activity Study of Health: Increasing Physical Activity in Aging
Northeastern University
NCT04315363
Mindfulness Meditation in Older Adults
University of California, Los Angeles
NCT01532596
HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults
University of Florida
NCT05583578
SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults
University of Florida
NCT05377411
Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
Florida State University
NCT05922475
Interval Training, Inflammation and Immune Function
Duke University
NCT02441205
Buck Institute Ketone Ester RCT
Buck Institute for Research on Aging
NCT05585762
Nitrate and Exercise Performance in Middle to Older Aged Adults
Wake Forest University
NCT03371966
Optimizing tDCS to Improve Dual Task Gait and Balance
Hebrew SeniorLife
NCT04295798
Inspiratory Muscle Training in Postmenopausal Women
Indiana University
NCT06459674
Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study
Ohio University
NCT03548168
Developing a Trauma-focused Intervention for Older Adults Living With HIV
University of South Carolina
NCT05287230
Exercise Effects on Word Learning
VA Office of Research and Development
NCT03370471
SimpleC Wellness Platform With Social Robot Interaction
SimpleC
NCT05296239
The Effects of Exercise on Sleep and Brain Health
Massachusetts General Hospital
NCT04210882
Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults
Colorado State University
NCT03824041
Novel Methodology to Measure Protein Accumulation
Mayo Clinic
NCT01505621
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Sara Espinoza
NCT03119610
Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging
Ball State University
NCT05872139
Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock
The University of Texas Health Science Center at San Antonio
NCT04608448
Aging and Gastrointestinal Barrier Function
University of Texas Southwestern Medical Center
NCT05816551
Coconut Sugar Lowers Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Ball State University
NCT05645991
Brain Changes With Game Training in Aging
University of Wisconsin, Madison
NCT02490137
Sex Differences in Vascular Responses to Exercise
University of Florida
NCT04128215
Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population
Leryn Reynolds
NCT04812392
Aerobic Exercise to Improve Executive Language Function In Older Adults
US Department of Veterans Affairs
NCT00979069
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Aging records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Aging trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Aging page
263 registered trials, 126 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 126 Aging trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Florida sponsors the most Aging trials on record, review their full trial history before evaluating a specific study. See University of Florida's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Aging condition card totals 263 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.