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Aging clinical trials
126 of 263 indexed Aging trials are currently recruiting.
263 US clinical trials · 126 currently recruiting
Aging is the subject of 263 registered US clinical trials on ClinicalTrials.gov, 126 of them currently open to new participants. 14 are in Phase 3-4 (later-stage) and 48 in Phase 1-2 (earlier-stage). The most active sponsor is University of Florida, running 14 of these trials.
The research picture
Aging has 263 registered US clinical trials, 126 of them open to new participants right now, about 48% of the total.
- 126
- recruiting participants now
- 48%
- of trials open to enrollment
- 14
- in Phase 3–4 (later-stage)
- 14
- top sponsor: University of Florida
Active & Recent Trials
263 total, page 5 of 6
Effect of Music and Other Audio Recordings for Chronic Pain in Aging Adults
Baylor University
NCT04785963
Nitrites, Skeletal Muscle Mitochondrial Bioenergetics, and Physical Activity in Old Age
Gladwin, Mark, MD
NCT04405180
The Short-term Effects of Noninvasive Electrical Brain Stimulation on Dual Tasking in Older Adults
Hebrew SeniorLife
NCT03191812
The Effect of Long Duration Exercise on the Diastolic Function of the Heart
University of Texas Southwestern Medical Center
NCT02039154
Mindfulness Training in Healthy Older Veterans
VA Office of Research and Development
NCT02816723
Variability of Physical Assessments in an Older Population That is Overweight or Obese
Versanis Bio
NCT05174923
Effect of Resvida, a Comparison With Calorie Restriction Regimen
Washington University School of Medicine
NCT00823381
Biologic Effects of Dehydroepiandrosterone (DHEA) in Humans
National Institute on Aging (NIA)
NCT00099697
Program for African American Cognition & Exercise
Pennington Biomedical Research Center
NCT03474302
E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons
Klein Buendel
NCT05017129
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial
University of Southern California
NCT00605072
The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age
Big Bold Health, PBC
NCT05234203
Cognitive Behavior Therapy (CBT)-Based Group Intervention to Reduce Inflammation in Older People With HIV
Massachusetts General Hospital
NCT05434741
Breathing Room Intervention to Achieve Better Lung Health in Older Adults
University of Wisconsin, Milwaukee
NCT05330780
Emotion Study/Substudy: Flexible Brain Study
University of Florida
NCT03872414
The Effect of the DASH Diet Containing Meat on Muscle and Metabolic Health in Older Adults
South Dakota State University
NCT04127240
Cell Signaling and Resistance to Oxidative Stress: Effects of Aging and Exercise
Northern Arizona University
NCT03419988
NanoSilk Cosmo: Evaluation of a Novel Silk Complex on Biophysical Parameters Related to Skin Aging
University of Colorado, Denver
NCT04630418
The Effects of Added Sugar Intake on Brain Blood Flow and Hippocampal Function in Midlife Adults
University of Delaware
NCT05211726
CALERIE (Tufts) - Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy
National Institute on Aging (NIA)
NCT00099099
Cognitive Effects of Transcranial Direct Current Stimulation in Older Adults
Johns Hopkins University
NCT01611103
Role of Centrum® Silver® in Improving Micronutrient Status in Older Men
Oregon State University
NCT03004807
The Influence of Regular Beef Consumption and Protein Density of the Diet on Training-induced Gains in Muscle Strength and Performance in Healthy Adults
University of Illinois at Urbana-Champaign
NCT03029975
Evaluation of Efficacy, Tolerability, and Pharmacokinetics of MYMD1 for Chronic Inflammation and Sarcopenia/Frailty
TNF Pharmaceuticals
NCT05283486
Daily Activity Study of Health: Increasing Physical Activity in Aging
Northeastern University
NCT04315363
Mindfulness Meditation in Older Adults
University of California, Los Angeles
NCT01532596
HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults
University of Florida
NCT05583578
SMART Stimulation: Precision Neuromodulation of Cognition in Older Adults
University of Florida
NCT05377411
Efficacy of Pre-sleep or Post-exercise Protein During 12 Weeks of Resistance Exercise Training
Florida State University
NCT05922475
Interval Training, Inflammation and Immune Function
Duke University
NCT02441205
Buck Institute Ketone Ester RCT
Buck Institute for Research on Aging
NCT05585762
Nitrate and Exercise Performance in Middle to Older Aged Adults
Wake Forest University
NCT03371966
Optimizing tDCS to Improve Dual Task Gait and Balance
Hebrew SeniorLife
NCT04295798
Inspiratory Muscle Training in Postmenopausal Women
Indiana University
NCT06459674
Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study
Ohio University
NCT03548168
Developing a Trauma-focused Intervention for Older Adults Living With HIV
University of South Carolina
NCT05287230
Exercise Effects on Word Learning
VA Office of Research and Development
NCT03370471
SimpleC Wellness Platform With Social Robot Interaction
SimpleC
NCT05296239
The Effects of Exercise on Sleep and Brain Health
Massachusetts General Hospital
NCT04210882
Effects of Aronia Berries on Vascular Endothelial Function and the Gut Microbiota in Middle-Aged/Older Adults
Colorado State University
NCT03824041
Novel Methodology to Measure Protein Accumulation
Mayo Clinic
NCT01505621
The Physiologic Effects of Intranasal Oxytocin on Sarcopenic Obesity
Sara Espinoza
NCT03119610
Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging
Ball State University
NCT05872139
Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock
The University of Texas Health Science Center at San Antonio
NCT04608448
Aging and Gastrointestinal Barrier Function
University of Texas Southwestern Medical Center
NCT05816551
Coconut Sugar Lowers Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Ball State University
NCT05645991
Brain Changes With Game Training in Aging
University of Wisconsin, Madison
NCT02490137
Sex Differences in Vascular Responses to Exercise
University of Florida
NCT04128215
Physical Inactivity Impacts on Blood Vessel Health and Glucose Levels in an Aging Population
Leryn Reynolds
NCT04812392
Aerobic Exercise to Improve Executive Language Function In Older Adults
US Department of Veterans Affairs
NCT00979069
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 29 |
| Phase 2 | 19 |
| Phase 3 | 6 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Aging Trial Landscape
263 indexed Aging studies · 126 recruiting (48%).
Phase mix: 14 late (III/IV) vs 48 early (I/II).
Top sponsor: University of Florida (14 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Aging?
PlainTrial tracks 263 US clinical trials for Aging, of which 126 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Aging?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.