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NCT04112667 · ClinicalTrials.gov registry record
Functionally Validated Structural Endpoints for Early AMD
A clinical trial of Aging and Age-related Macular Degeneration, sponsored by Cynthia Owsley.
- Completed
- Registry status
- 556
- Enrollment target
- 1
- Study location
NCT04112667 is a study of Aging and Age-related Macular Degeneration that has completed, run by Cynthia Owsley. The registered enrollment target is 556 participants, below the 2,193-participant average among 262 other Aging trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04112667, a study of Aging and Age-related Macular Degeneration, has completed, sponsored by Cynthia Owsley.
- COMPLETED
- Registry status
- 556 participants
- Enrollment target
- 1
- Study location
Study Summary
Delayed rod-mediated dark adaptation (RMDA), or delayed recovery of vision in a dark environment, is a functional biomarker (i.e., risk factor) for early age-related macular degeneration (AMD). This research plan is designed to elucidate the structural (anatomical) basis of this visual deficit using cellular- and subcellular level imaging of the retina and its supporting tissues in living people. An accurate map and timeline of structure-function relationships in persons tested for night vision will result in functionally validated structural endpoints for early AMD trials, as well as define major biologic effects for development into future treatments.
Conditions Studied
Interventions
- OTHER Normal Macular Health
- OTHER Early Macular Degeneration
- OTHER Young Normals
Study Locations (1)
Alabama
- University of Alabama at Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 556 participants |
| Start Date | 2019-10-07 |
| Est. Completion | 2024-10-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04112667
The ClinicalTrials.gov registry entry for NCT04112667 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 556 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,193-participant average among 262 other Aging trials with a reported enrollment target (75% lower). The listed sponsor is Cynthia Owsley, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Aging appearing as the primary indexed condition, and to 3 interventions - of which Normal Macular Health is the first listed.
NCT04112667 reports 1 study location spanning 1 distinct geographic area - top geographies include Alabama.
Frequently Asked Questions
What is clinical trial NCT04112667 about?
NCT04112667 is a clinical study titled "Functionally Validated Structural Endpoints for Early AMD". Delayed rod-mediated dark adaptation (RMDA), or delayed recovery of vision in a dark environment, is a functional biomarker (i.e., risk factor) for early age-related macular degeneration (AMD). This research plan is designed to elucidate the structural (anatomical) basis of this visual deficit using...
What is the current status of trial NCT04112667?
This trial is currently completed. The enrollment target is 556 participants. The study started on 2019-10-07. Estimated completion is 2024-10-31.
What conditions does trial NCT04112667 study?
This clinical trial studies the following conditions: Aging, Age-related Macular Degeneration.
What interventions are being tested in trial NCT04112667?
The interventions under investigation include: Normal Macular Health (OTHER), Early Macular Degeneration (OTHER), Young Normals (OTHER).
Who is sponsoring clinical trial NCT04112667?
This trial is sponsored by Cynthia Owsley, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04112667 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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