VA Office of Research and Development

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, VA Office of Research and Development sits in the top decile of US sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count).

1,668 total trials 291 currently recruiting 1108 completed early-phase tilt top decile by trial count

VA Office of Research and Development: 1,668 sponsored US clinical trials, 291 recruiting.

VA Office of Research and Development sponsors 1,668 registered US clinical trials on ClinicalTrials.gov, 291 of them currently recruiting, and 1,108 completed. 124 of these trials are in Phase 3-4 (later-stage) and 236 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is PTSD, with 28 trials.

Top-decile sponsor footprint

VA Office of Research and Development ranks in the top decile of sponsors by registered trial count (#11 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

1,668 total, page 6 of 34

RECRUITING NA

Development of a Recovery Oriented Treatment for Post-Acute Suicidal Episode (PASE) Veterans

NCT04731519

RECRUITING NA

National Sponsorship Program for Transitioning Service Members

NCT05224440

RECRUITING

Improving Socket Fit in Female and Male Veterans With Transtibial and Transfemoral Amputation

NCT05989243

RECRUITING NA

Functional Outcomes of Cannabis Use (FOCUS) in Veterans With Posttraumatic Stress Disorder

NCT04565028

RECRUITING Phase 3

Behavioral Activation Delivered Via Home-based Telehealth to Improve Functioning in Cardiovascular Disease Patients Recently Discharged From Inpatient Care

NCT04877197

RECRUITING NA

Manage Emotions to Reduce Aggression (MERA)

NCT04793776

RECRUITING NA

rTMS-augmented Written Exposure Therapy for PTSD

NCT05149534

RECRUITING NA

Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

NCT05028972

RECRUITING NA

Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses

NCT04947462

RECRUITING NA

Exercise Therapy for PAD Using Mobile Health

NCT04889105

RECRUITING NA

Responses to Backward Walking Training Post-Stroke

NCT04928482

RECRUITING NA

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806

RECRUITING Phase 2

Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial

NCT04982419

RECRUITING Phase 2

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

NCT05011383

RECRUITING Early Phase 1

Exercise Primed Stroke Rehabilitation

NCT04877444

RECRUITING Phase 2

Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

NCT04787744

RECRUITING

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

NCT04124029

RECRUITING Phase 1

Novel Approaches for Improving Vascular Function in Veterans With HFpEF

NCT06312748

RECRUITING NA

Functional and Neuroprotective Effects of Restoring Lower Limb Sensation After Diabetic Peripheral Neuropathy

NCT04658693

RECRUITING NA

Vagal Nerve Stimulation in mTBI

NCT04437498

RECRUITING NA

Blood Pressure Slopes and Ultrafiltration in Hemodialysis Patients

NCT04163614

RECRUITING NA

Effects of tDCS Combined With CBI on Postsurgical Pain

NCT04199780

RECRUITING Phase 4

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

NCT04118387

RECRUITING NA

Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

NCT04179981

RECRUITING Phase 4

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

NCT04375033

RECRUITING NA

EMG Controlled Device in Acute Rehabilitation After Acute Stroke

NCT04599036

RECRUITING NA

Peripheral Interfaces in Amputees for Sensorimotor Integration

NCT04430218

RECRUITING NA

Successful Transitions and Reintegration Tools for Veterans (START-VETS)

NCT04366531

RECRUITING NA

Hybrid Pump Technology

NCT04230512

RECRUITING Phase 1

rTMS to Improve Cognition in Parkinson's

NCT03836950

RECRUITING NA

Brain Connections for Arm Movement After Stroke

NCT04286516

RECRUITING NA

Detection and Amelioration of Gamma Oscillation Abnormalities in Blast-Related Brain Injury

NCT03836976

RECRUITING NA

Optimizing Gait Rehabilitation for Veterans With Non-traumatic Lower Limb Amputation

NCT03995238

RECRUITING Phase 2

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

NCT04038502

RECRUITING Phase 4

Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress

NCT03642028

RECRUITING Phase 1

Sleep Disordered Breathing With Opioid Use

NCT05589753

RECRUITING NA

Improving Measurement and Treatment of Post-stroke Neglect

NCT03317860

RECRUITING NA

Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

NCT02984761

RECRUITING NA

Neurocognitive and Health Impact of Sleep Apnea in Elderly Veterans With Comorbid COPD

NCT02703207

RECRUITING Phase 4

Sleep Apnea in Elderly

NCT02703220

RECRUITING NA

A Neuroprosthesis for Seated Posture and Balance

NCT01474148

ACTIVE NOT RECRUITING NA

At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers

NCT06312579

ACTIVE NOT RECRUITING NA

Implementation of Collaborative Care for Depression in VA HIV Clinics

NCT05901272

ACTIVE NOT RECRUITING NA

Promoting Cognitive Resilience and Reducing Frailty in Older Veterans With Bright Light Therapy

NCT05631236

ACTIVE NOT RECRUITING NA

Narrative Discourse Treatment Development

NCT05008419

ACTIVE NOT RECRUITING NA

Telehealth-delivered Peer Support to Improve Quality of Life Among Veterans With Multimorbidity

NCT05560451

ACTIVE NOT RECRUITING NA

Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Therapy

NCT05797441

ACTIVE NOT RECRUITING NA

An eHealth Intervention to Increase Depression Treatment Initiation and Adherence Among Veterans Referred for Mental Health Services

NCT05990075

ACTIVE NOT RECRUITING NA

Fatigability in Long COVID-19

NCT05699538

ACTIVE NOT RECRUITING NA

A Randomized Trial of Behaviorally Designed Gamification and Social Incentives to Increase Physical Activity Among Overweight and Obese Veterans

NCT05554601

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Phase Distribution

PhaseTrial count
Phase 1 89
Phase 2 147
Phase 3 55
Phase 4 69

What is open in the VA Office of Research and Development pipeline

291 recruiting of 1,668 indexed (17% open); 1,108 completed (66%).

Phase mix: 124 late (III/IV) vs 236 early (I/II) (early-phase heavy).

Top condition: PTSD (28 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.