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NCT04179981 · ClinicalTrials.gov registry record · NA
Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)
A NA study of Obstructive Sleep Apnea and Quality of Life, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 668
- Enrollment target
- 1
- Study location
NCT04179981: Recruiting NA study of Obstructive Sleep Apnea and Quality of Life, sponsored by VA Office of Research and Development.
NCT04179981 is a NA study of Obstructive Sleep Apnea and Quality of Life that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 668 participants, above the 217-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (208% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04179981, a NA study of Obstructive Sleep Apnea and Quality of Life, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 668 participants
- Enrollment target
- 1
- Study location
Study Summary
Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is highly prevalent in Veterans. Veterans with OVS may be at increased risk for cognitive deficits, poor sleep quality as well as a reduced quality of life (QoL). The overall objective is to study the effects of positive airway pressure therapy on clinical outcomes in patients with OVS.
Primary Outcome
Trails A and Trails B test will be administered to evaluate attention and psychomotor function. This score is adjusted for age, race, gender, and years of education. Scored on a Standard scale of 100 +/- 15 for normal ranges, above 115 is above average, below 85 is considered below average.
Conditions Studied
Interventions
- DEVICE Positive airway pressure
- OTHER Conservative care (control arm)
Study Locations (1)
Michigan
- John D. Dingell VA Medical Center, Detroit, MI - Detroit
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 668 participants |
| Start Date | 2020-12-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT04179981 shows while recruiting
NCT04179981 is an interventional study that assigns participants to a tested intervention. The registered 668 participants enrollment target is mid-sized for trials with a published cap, above the 217-participant average among 155 other Obstructive Sleep Apnea trials with a reported enrollment target (208% higher).
The record links to 9 conditions, with Obstructive Sleep Apnea appearing as the primary indexed condition, and to 2 interventions - of which Positive airway pressure is the first listed.
NCT04179981 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT04179981 about?
NCT04179981 is a clinical study titled "Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)". Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is h...
What is the current status of trial NCT04179981?
This trial is currently recruiting. It is a NA study. The enrollment target is 668 participants. The study started on 2020-12-01. Estimated completion is 2026-12-31.
What conditions does trial NCT04179981 study?
This clinical trial studies the following conditions: Obstructive Sleep Apnea, Quality of Life, COPD, Neurocognitive Function, Elderly.
What interventions are being tested in trial NCT04179981?
The interventions under investigation include: Positive airway pressure (DEVICE), Conservative care (control arm) (OTHER).
Who is sponsoring clinical trial NCT04179981?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04179981 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04179981's enrollment target sits among peer trials
668 10th of 155 higher than 146 of 155 other Obstructive Sleep Apnea trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Obstructive Sleep Apnea trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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