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NCT04947462 · ClinicalTrials.gov registry record · NA
Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses
A NA study of Upper Limb Amputees, sponsored by VA Office of Research and Development.
- Recruiting
- Registry status
- NA
- Development phase
- 6
- Enrollment target
- 1
- Study location
NCT04947462: Recruiting NA study of Upper Limb Amputees, sponsored by VA Office of Research and Development.
NCT04947462 is a NA study of Upper Limb Amputees that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04947462, a NA study of Upper Limb Amputees, is actively recruiting participants, sponsored by VA Office of Research and Development.
- RECRUITING
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advanced controllers for moving a prosthesis. Proprioceptive sensations are the sensations that tell individuals where their hand is in space, and if it is moving. The research team uses Functional Electrical Stimulation (FES), which involves applying small electric currents to the nerves. These signals are then transferred to the brain just like the information about the individual's intact hand used to be transferred to their brain. This study will test different placements for stimulation and determine which one(s) provide the individual with proprioceptive sensations. The investigators want to know what the participants feel and if the investigators can use proprioceptive sensation to give the participants information about limb movement and position.
Primary Outcome
Magnitude of change in perceived joint position, as measured by joint angle transducers in the Cyberglove. As well as just noticeable difference (JND) of perceived magnitude, JND of perceived frequency, temporal detection threshold (TDT), and adaptation time constants for proprioceptive percepts
Conditions Studied
Interventions
- DEVICE Chronically Implanted Neural and Muscular Interface
Study Locations (1)
Ohio
- Louis Stokes VA Medical Center, Cleveland, OH - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2021-12-01 |
| Est. Completion | 2026-09-30 |
| Phase | NA |
What NCT04947462 shows while recruiting
NCT04947462 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Upper Limb Amputees appearing as the primary indexed condition, and to 1 intervention - of which Chronically Implanted Neural and Muscular Interface is the first listed.
NCT04947462 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT04947462 about?
NCT04947462 is a clinical study titled "Proprioceptive Sensorimotor Integration With Neural Interfaces for Hand Prostheses". The purpose of this study is to characterize proprioceptive sensations in the missing limb of upper limb amputees using nerve stimulation, and to develop advanced controllers for moving a prosthesis. Proprioceptive sensations are the sensations that tell individuals where their hand is in space, and...
What is the current status of trial NCT04947462?
This trial is currently recruiting. It is a NA study. The enrollment target is 6 participants. The study started on 2021-12-01. Estimated completion is 2026-09-30.
What conditions does trial NCT04947462 study?
This clinical trial studies the following conditions: Upper Limb Amputees.
What interventions are being tested in trial NCT04947462?
The interventions under investigation include: Chronically Implanted Neural and Muscular Interface (DEVICE).
Who is sponsoring clinical trial NCT04947462?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04947462 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04947462's enrollment target sits among peer trials
6 1984th of 2000 higher than 13 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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