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NCT04124029 · ClinicalTrials.gov registry record

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

A clinical trial of Mild Cognitive Impairment and Mild Traumatic Brain Injury, sponsored by VA Office of Research and Development.

Recruiting
Registry status
800
Enrollment target
1
Study location

NCT04124029 is a study of Mild Cognitive Impairment and Mild Traumatic Brain Injury that is actively recruiting participants, run by VA Office of Research and Development. The registered enrollment target is 800 participants, below the 1,267-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (37% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT04124029, a study of Mild Cognitive Impairment and Mild Traumatic Brain Injury, is actively recruiting participants, sponsored by VA Office of Research and Development.

RECRUITING
Registry status
800 participants
Enrollment target
1
Study location

Study Summary

This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain structure and proteins that can be elevated after brain injury and in dementia.

Conditions Studied

Mild Cognitive Impairment Mild Traumatic Brain Injury Moderate Traumatic Brain Injury

Interventions

  • DEVICE No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan.
  • PROCEDURE No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.

Study Locations (1)

Massachusetts

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA - Boston

Trial Details

FieldValue
Enrollment Target 800 participants
Start Date 2021-07-01
Est. Completion 2026-06-30

Sponsor

VA Office of Research and Development

1,668 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT04124029

The ClinicalTrials.gov registry entry for NCT04124029 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 800 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,267-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (37% lower). The listed sponsor is VA Office of Research and Development, which has 1,668 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 2 interventions - of which No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan. is the first listed.

NCT04124029 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT04124029 about?

NCT04124029 is a clinical study titled "Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)". This is a research study that aims to examine whether Veterans with mild Traumatic Brain Injuries are at risk for dementia by studying their memory, brain wave activity, brain structure and proteins that can be elevated after brain injury and in dementia.

What is the current status of trial NCT04124029?

This trial is currently recruiting. The enrollment target is 800 participants. The study started on 2021-07-01. Estimated completion is 2026-06-30.

What conditions does trial NCT04124029 study?

This clinical trial studies the following conditions: Mild Cognitive Impairment, Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury.

What interventions are being tested in trial NCT04124029?

The interventions under investigation include: No Intervention is used for this study but all subjects will be asked to complete EEG testing and an MRI scan. (DEVICE), No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure. (PROCEDURE).

Who is sponsoring clinical trial NCT04124029?

This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04124029 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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